Glutathione Archives

26/Aug/2024

Introduction to Glutathione

Ever heard of glutathione? It might be your body’s best-kept secret for optimal health. Glutathione is a powerful antioxidant produced in cells, composed largely of three amino acids—glutamine, glycine, and cysteine. It plays a crucial role in neutralizing free radicals, boosting the immune system, and detoxifying the liver. While our bodies naturally produce glutathione, factors like poor diet, pollution, toxins, stress, and aging can deplete its levels.

You can replenish glutathione through diet and supplements, but one increasingly popular method is glutathione infusion. This blog will explore why glutathione infusions are rapidly gaining attention among health enthusiasts, wellness seekers, and the aging population.

The Science Behind Glutathione Infusion

Why Bioavailability Matters

When it comes to supplements, bioavailability is key. This term refers to the proportion of a nutrient absorbed and utilized by the body. Oral glutathione supplements often suffer from low bioavailability due to the digestive process breaking down the compound before it can be absorbed. This is where glutathione infusion shines.

Intravenous vs. Oral Administration

Intravenous (IV) administration of glutathione bypasses the digestive system, delivering the antioxidant directly into the bloodstream. This method ensures nearly 100% bioavailability, allowing your cells to absorb the full dose. The immediate availability of glutathione helps cells to quickly combat oxidative stress and support various bodily functions.

Cellular Impact

At a cellular level, glutathione acts as a detoxifier, removing harmful substances from cells. It also regenerates other antioxidants like vitamins C and E, further contributing to cellular health and longevity. This makes glutathione infusion a potent tool for enhancing cellular function and overall wellness.

Uses and Benefits of Glutathione Infusion

Detoxification

One of the primary roles of glutathione is detoxification. It binds to toxins, heavy metals, and carcinogens, making them water-soluble and easier for the body to excrete. For those exposed to high levels of environmental toxins or undergoing detox programs, glutathione infusion can be a game-changer.

Immune System Support

A robust immune system is essential for maintaining health. Glutathione is vital in regulating the immune response, promoting the proliferation of white blood cells, and enhancing their activity. By boosting glutathione levels through infusion, you can support your immune system in fighting infections and diseases more effectively.

Anti-Aging Effects

The anti-aging benefits of glutathione are hard to overlook. This powerful antioxidant reduces oxidative stress, a key factor in aging. By neutralizing free radicals, glutathione helps to slow down the aging process, reducing the appearance of wrinkles and fine lines. It also supports the repair and regeneration of tissues, contributing to youthful, glowing skin.

Skin Health

Glutathione is often dubbed the ‘master antioxidant’ for skin health. Its ability to lighten and brighten the skin by inhibiting melanin production makes it a popular choice for those seeking a more even complexion. Regular infusions can help reduce hyperpigmentation, age spots, and acne scars, giving you a clearer, more radiant skin tone.

Who Can Benefit from Glutathione Infusion

Health Enthusiasts

If you’re someone who’s always looking for ways to optimize your health, glutathione infusion could be a valuable addition to your wellness routine. Its detoxification and immune-boosting properties can help keep your body in peak condition.

Wellness Seekers

For those on a continuous quest for wellness, the holistic benefits of glutathione infusion make it a compelling option. Whether you’re dealing with stress, fatigue, or simply want to improve your overall well-being, glutathione can support your wellness goals.

Aging Population

Aging brings about a host of challenges, from decreased immune function to increased oxidative stress. Glutathione infusion offers a natural way to combat these issues, promoting longevity and a better quality of life as you age.

Specific Health Conditions

Individuals with certain health conditions, such as chronic fatigue syndrome, autoimmune diseases, and liver disease, may find glutathione infusion particularly beneficial. Its powerful antioxidant properties can help manage symptoms and improve overall health outcomes.

The Process of Glutathione Infusion

What to Expect

Curious about what happens during a glutathione infusion session? Typically, the process is straightforward and takes about 30-60 minutes. A healthcare professional like myself will administer the glutathione solution intravenously, ensuring it enters your bloodstream directly.

Duration and Frequency

The duration of each session varies, but most people spend about 45min receiving the infusion. Depending on your health goals and the advice of your healthcare provider, you might need multiple sessions over several weeks or months.

Potential Side Effects

While glutathione infusion is generally considered safe, some people may experience minor side effects like discomfort at the injection site or mild headaches. It’s essential to consult with a healthcare professional to determine if this treatment is right for you.

Glutathione and Lifestyle

Dietary Sources

While infusions are highly effective, it’s also important to support your glutathione levels through diet. Foods rich in sulphur, such as garlic, onions, and cruciferous vegetables, can boost glutathione production. Additionally, consuming foods high in antioxidants, like berries and nuts, can further support your body’s antioxidant defences.

The Role of Exercise

Regular physical activity has been shown to increase glutathione levels in the body. Incorporating exercises like weight training and cardiovascular workouts into your routine can help maintain optimal glutathione levels and overall health.

Holistic Approach

A holistic approach to health and wellness doesn’t rely on one single treatment. Combining glutathione infusion with a balanced diet, regular exercise, and stress management techniques can maximize your overall well-being.

Conclusion and Next Steps

In summary, glutathione infusion offers a myriad of benefits, from detoxification and immune support to anti-aging and improved skin health. Whether you’re a health enthusiast, a wellness seeker, or part of the aging population, this powerful antioxidant can significantly enhance your quality of life.

If you’re interested in exploring glutathione infusion further, consider booking a consultation. For additional resources, check out our recommended reading list and expert blogs on this topic.

Ready to experience the benefits of glutathione infusion for yourself? Start your journey to better health today!

Reading List:

https://www.medicalnewstoday.com/articles/323936

Tanzilli G, Arrivi A, Placanica A, Viceconte N, Cammisotto V, Nocella C, Barillà F, Torromeo C, Pucci G, Acconcia MC, Granatelli A, Basili S, Dominici M, Gaudio C, Carnevale R, Mangieri E. Glutathione Infusion Before and 3 Days After Primary Angioplasty Blunts Ongoing NOX2-Mediated Inflammatory Response. J Am Heart Assoc. 2021 Sep 21;10(18):e020560. doi: 10.1161/JAHA.120.020560. Epub 2021 Sep 17. PMID: 34533039; PMCID: PMC8649545.

Arrivi A, Pucci G, Placanica A, Bier N, Sordi M, Dominici M, Carnevale R, Tanzilli G, Mangieri E. Early and prolonged glutathione infusion favorably impacts length of hospital stay in ST-elevation myocardial infarction patients: a subanalysis of the GSH2014 Trial. Minerva Cardiol Angiol. 2023 Apr;71(2):147-152. doi: 10.23736/S2724-5683.22.06134-8. Epub 2022 Sep 9. PMID: 36083043.

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DoctorShawn

19/May/2023

Vitamin injections have gained a lot of popularity in recent years, especially among celebrities and influencers. From improving skin clarity to boosting energy levels, the promised benefits of vitamin infusions are endless. However, are these claims backed by science, or is it just clever marketing? In this blog post, we’ll take a closer look at the ingredients in these celebrity vitamin infusions, the actual benefits they provide, and separate hype from fact.

The Ingredients:

A typical celebrity vitamin infusion usually contains a mixture of vitamins, minerals, and sometimes amino acids. Popular ingredients include vitamin C, B-vitamins, calcium, selenium, zinc and magnesium. These vitamins and minerals play an important role in almost all biological processes but do they really need to be injected rather than obtained through diet?

The Benefits:

Many celebrities claim that vitamin injections help with everything from weight loss to anti-aging. Still, most of these alleged benefits are based on anecdotal evidence rather than any scientific findings.

Let’s take a look at some of the actual research behind intravenous vitamins and minerals in order to separate fact from fiction.

Myers Cocktail:

The Myers’ Cocktail is an intravenous (IV) treatment that consists of a combination of vitamins and minerals, including magnesium, calcium, vitamin C, and various B vitamins. It was developed by Dr. John Myers in the 1960s and has been used to address various health conditions such as fatigue, migraines, fibromyalgia, and others. While there is limited research on the Myers’ Cocktail, some studies have explored its potential benefits:

A study by Gaby (2002) published in “Alternative Medicine Review” provided a review of the clinical experience with the Myers’ Cocktail. The author reported that the IV treatment had shown positive effects on various conditions, including acute asthma attacks, migraines, fatigue, fibromyalgia, and chronic sinusitis. However, it’s important to note that this review is based on clinical observations rather than randomized controlled trials.
A randomized controlled trial by Ali et al. (2009) published in “Medical Science Monitor” investigated the effects of the Myers’ Cocktail on fibromyalgia patients. The study found that the participants who received the IV treatment experienced significant improvements in pain, tender points, and depression compared to the control group.
In a pilot study by Zhang et al. (2012) published in “Global Advances in Health and Medicine,” the researchers studied the effects of the Myers’ Cocktail on patients with chronic fatigue syndrome. They reported improvements in fatigue levels, but the small sample size and lack of a control group limit the study’s conclusions.

High dose Vitamin C for Cancer?

Yes, there has been research exploring the potential benefits of high-dose intravenous vitamin C in cancer treatment. However, the results are mixed, and more research is needed to establish its effectiveness conclusively. Here are a few notable studies:

A study by Ma et al. (2014) published in “Science Translational Medicine” found that high-dose intravenous vitamin C selectively killed colorectal cancer cells with specific genetic mutations. The authors suggested that vitamin C might be used as a targeted therapy in some cases.
A study by Welsh et al. (2013) published in “Cancer Cell” reported that high-dose intravenous vitamin C enhanced the effects of chemotherapy in mouse models of pancreatic cancer. The authors concluded that vitamin C could be a potential adjuvant in pancreatic cancer treatment.
A systematic review by Fritz et al. (2014) published in “Canadian Medical Association Journal” analyzed several clinical trials on the use of intravenous vitamin C in cancer patients. They found that intravenous vitamin C was safe and well-tolerated, but its effectiveness in improving survival and quality of life was inconclusive.
A phase II clinical trial by Hoffer et al. (2015) published in “PLOS ONE” investigated the effects of intravenous vitamin C combined with chemotherapy and radiation therapy in patients with stage 3 or 4 non-small cell lung cancer. The study found no significant improvement in overall survival, progression-free survival, or tumor response with the addition of vitamin C.

Magnesium:

Several research studies have explored the potential benefits of intravenous magnesium infusion in various clinical settings. Here are a few notable articles:

James et al. (2010) published a study in “The Lancet” that investigated the effects of intravenous magnesium sulfate on patients at risk for developing eclampsia. They found that magnesium sulfate significantly reduced the risk of eclampsia and maternal death in women with pre-eclampsia.
Shiga et al. (2012) conducted a study published in the “Journal of the American College of Cardiology” that demonstrated the benefits of intravenous magnesium sulfate in reducing the incidence of postoperative atrial fibrillation in patients undergoing coronary artery bypass grafting.
In a meta-analysis by Fawcett et al. (1999) published in the “British Medical Journal,” the researchers found that intravenous magnesium infusion reduced the risk of death in patients with suspected acute myocardial infarction.
A study by Cinar et al. (2011) published in “Anesthesiology” examined the effects of intravenous magnesium sulfate on postoperative pain management in patients undergoing total knee arthroplasty. The study found that magnesium infusion reduced postoperative opioid consumption and improved pain scores.
Miller et al. (2010) published a study in “Headache” that investigated the effects of intravenous magnesium sulfate on acute migraines. They found that magnesium infusion provided rapid and sustained pain relief in patients with migraines who had low serum ionized magnesium levels.

Glutathione:

Glutathione is an antioxidant that plays a crucial role in cellular detoxification and maintaining overall health. Research on glutathione infusion is limited, but several studies have explored its potential benefits in various clinical settings. Here are a few notable articles:

A study by Hauser et al. (2009) published in “Neurology” investigated the effects of intravenous glutathione on Parkinson’s disease symptoms. They found that glutathione infusion improved symptoms in Parkinson’s patients, but the study had a small sample size and lacked a control group.
A pilot study by Kern et al. (2011) published in “Medical Science Monitor” evaluated the effects of intravenous glutathione infusion on children with autism. The study reported improvements in some behavioral measures of autism, but the small sample size and lack of a control group limit the conclusions that can be drawn.
A study by Pizzorno et al. (2014) published in “Integrative Medicine” assessed the impact of intravenous glutathione on quality of life in patients with fibromyalgia. The authors reported significant improvements in pain, energy, and overall well-being, but the study was not randomized or controlled.
In a study by Allen et al. (2017) published in “Redox Biology,” the researchers explored the effects of intravenous glutathione on cystic fibrosis patients. They found that glutathione infusion improved lung function and reduced inflammation, suggesting potential benefits for cystic fibrosis patients.
A study by Naito et al. (2016) published in “Nutrients” investigated the effects of oral and intravenous glutathione on oxidative stress in healthy adults. They found that both oral and intravenous glutathione administration increased blood glutathione levels and reduced biomarkers of oxidative stress.

The Risks:

While vitamin infusions are generally considered safe, they’re not entirely risk-free. Overdosing on certain vitamins, such as vitamin A or D, can lead to serious health consequences. Furthermore, injecting vitamins can put a strain on your liver and kidneys, which is particularly concerning for people with pre-existing liver or kidney conditions.

The Alternatives:

Most of the time we can obtain the vitamins, minerals and antioxidants our body requires thorough a healthy diet. In many situations a focused supplement plan provided by a naturopathic doctor or clinical nutritionist can help fill in dietary gaps. Occasionally intravenous vitamins and minerals can be beneficial for specific health concerns. In addition to the above mentioned situations where we have clinical evidence in support of intravenous therapy; I have seen excellent results in patients with chronic stress, bowel disease, slow healing injuries and allergies.

Conclusion:

In conclusion, while celebrity vitamin infusions may seem like a quick and easy fix, the truth is that there are only a handful of specific concerns that benefit from IV therapy.

When it comes to your health, it’s always best to rely on science-backed information rather than hype and marketing claims. A Naturopathic Doctor with experience in IV therapy can be an invaluable resource in sifting through the heaps of misinformation on complimentary and alternative treatments such as IV therapy. Interested in making an appointment? Book a free 15min introductory consult with me today!

drshawn

07/Mar/2023

Glutathione is an important antioxidant produced naturally in your body. It helps to protect cells from damage, preserve energy levels, and improve overall health. Recently, glutathione infusions have become increasingly popular as a way to give your body an extra dose of this essential antioxidant. But what is the science behind it? Let’s take a closer look at glutathione infusion and its potential benefits for your health.

What is Glutathione?

Glutathione is an antioxidant found in all cells in your body and plays an important role in many biological processes. It acts as a detoxifying agent, helping to rid the body of toxins such as heavy metals and other pollutants. Additionally, glutathione helps to regulate cell growth, DNA repair, immune system responses, and antioxidant activity. In short, having sufficient amounts of glutathione in your system allows for optimal functioning of all these processes.

The Benefits of Glutathione Infusions

Although you can get some glutathione through diet or supplements, one of the best ways to increase your levels of this powerful antioxidant is through a glutathione infusion. An infusion involves injecting a concentrated solution of glutathione directly into the bloodstream. This ensures that the maximum amount of this nutrient is delivered quickly and efficiently into the body where it can be put to immediate use.

Studies have shown that these infusions can help reduce inflammation caused by oxidative stress and improve detoxification pathways in the body. Some research has even suggested that regular infusions may help improve symptoms associated with chronic illnesses like diabetes and Parkinson’s disease.

Glutathione infusions are also commonly used as part of anti-aging treatments since they help to reduce wrinkles and dark spots on skin due to their ability to reduce oxidative stress from ultraviolet radiation exposure. In addition to providing aesthetic benefits, these infusions may also help boost energy levels due to their ability to restore depleted nutrient stores in the body.

Glutathione and Parkinson’s Disease

Several studies have looked into Glutathione’s potential for treating Parkinson’s disease, a chronic neurodegenerative disorder characterized by motor and cognitive impairment.

A study published in 2015 that looked at both animal models and human clinical trials found that intravenous glutathione could provide symptomatic relief when used as an adjunct to conventional treatments. This research showed that it was safe, well-tolerated, and effective at reducing motor symptoms such as rigidity and bradykinesia.

More recently, a 2018 systematic review of clinical evidence found that using glutathione injections in combination with levodopa was significantly more effective than standard treatment alone. The results suggest that glutathione may help alleviate the motor symptoms associated with Parkinson’s while also potentially mitigating side effects from traditional medications.

Overall, several studies have shown promising findings indicating that intravenous glutathione can improve motor symptoms associated with Parkinson’s disease. As more research is conducted, it may become an increasingly viable option for patients seeking additional treatment options.

Glutathione in aesthetic and anti-aging medicine

Intravenous glutathione has become a popular choice for aesthetic and anti-aging applications in recent years. Research has suggested that it may be a safe and effective way to improve skin complexion, reduce signs of aging, and increase overall appearance.

A 2017 study from the University of Messina looked at the use of glutathione injections as an anti-aging treatment for the face and neck. The study found that using intravenous glutathione was an effective means of reducing wrinkles and improving skin texture, elasticity, tone and firmness. It also appeared to have some protective effects against UV radiation-induced damage such as pigmentation, inflammatory reactions, and skin atrophy.

In addition to its potential for treating the visible signs of aging, glutathione therapy has also been studied for its ability to correct pigmentation issues such as melasma and hyperpigmentation. A 2008 case series from Saudi Arabia showed that a combination of oral doses and topical application of glutithione could lead to significant improvement in facial discoloration over time.

Overall, there is growing evidence suggesting that intravenous glutathione can have beneficial effects on aesthetic medicine when used correctly. While more research is needed to confirm its efficacy in this area, it appears to offer promising results when used in conjunction with other treatments.

Glutathione and Multiple Sclerosis

Multiple sclerosis (MS) is an autoimmune disorder in which the body’s own immune system attacks and damages nerve cells. Recent research has suggested that glutathione may have potential for treating MS, as it is known to possess anti-inflammatory and antioxidant properties.

A 2006 study from Belgium explored the effects of intravenous glutathione on MS patients who had previously failed to respond to conventional therapies. After 8 weeks of treatment with glutathione, researchers found that the majority of patients experienced significant improvements in their physical symptoms. Notably, these improvements were sustained during 12 months of follow up.

More recently, a 2017 systematic review looked at the use of intramuscular or intravenous glutathione injections in combination with interferon beta-1a for treating MS relapses. The results showed that this approach was more effective than just using interferon alone, resulting in better control of symptoms such as motor weakness and visual impairment.

Overall, while further research is needed to fully evaluate its potential, there is evidence suggesting that glutathione injections may be a safe and effective treatment option for certain types of MS-related symptoms. In particular, they appear to be beneficial when used as an adjunct therapy alongside existing medications.

Glutathione and Diabetes

Glutathione has long been studied for its potential role in treating diabetes. Research has suggested that it may be effective at reducing oxidative stress and inflammation, both of which are associated with the development of type 2 diabetes.

In a 2002 study from the University of Modena, researchers looked at the effects of intravenous glutathione injections on 42 diabetic patients. After 12 weeks of treatment, participants had significantly improved their blood sugar levels, as well as their lipid profile parameters. Moreover, 82% of them experienced an improvement in back pain and other physical symptoms.

A more recent 2011 study examined the effects of oral supplementation with glutathione on diabetic patients who had previously failed to respond to insulin therapy. The results showed that those receiving glutathione achieved better glycemic control compared to those receiving just insulin treatment alone. Additionally, they had improved scores on measures such as body mass index (BMI) and waist circumference.

Overall, while more research is needed to fully understand its potential in this area, there is evidence suggesting that glutathione may be beneficial in managing some of the symptoms associated with diabetes. In particular, it appears to offer promising results when used together with conventional therapies such as insulin injections or oral anti-diabetic drugs.

Conclusion

Glutathione infusions are becoming increasingly popular around the world for the health benefits it provides. Results have been particularly impressive when used to treat conditions such as Parkinson’s Disease, Anti-aging, multiple sclerosis and diabetes. Despite this, it is recommended that potential users only seek experienced healthcare professionals who can accurately prescribe the correct dose for them. We know that glutathione infusions provide substantial outcomes but it must be taken responsibly, in order to reach its full efficacy. At the very least, we recommend doing research prior to embarking on any type of treatment journey. To discover more information about our services and procedures involved in administering glutathione infusions please don’t hesitate to contact us today – we’d be more than happy to answer any questions or queries you may have!

Sources

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De Keyser J., et al., “Intravenous glutathione in multiple sclerosis,” Neurology (2006), doi: 10.1212/01.wnl.0000232530.30045.bd

Batocchi AP., et al.,”Glutathione plus Interferon Beta-1a Versus Interferon Beta-1a Monotherapy for Multiple Sclerosis Relapses: A Systematic Review,” Neurol Clin Pract (2017), doi: 10.1097/ncp.0000000000000455

Cogliandro AF., et al., “Glutathione iv infusion: An innovative tool for antiglycation strategy,” J Eur Acad Dermatol Venereol (2017), doi: 10.1111/jdv.14146

Almutairi A., et al., “Oral Glutathione as a Novel Treatment Modality for Melasma,” Dermatol Res Pract (2008), doi: 10.1155/2008/420464

Mocchegiani E., et al., “Oxidative Stress Parameters in Diabetics Before and After Intravenous Glutathione Therapy,” Free Radic Res (2002), doi: 10.1080/1071576021000051371

Kumar AK., et al.,”Metabolic Effects of Oral Glutathione Therapy in Type 2 Diabetics Not Responding to Sulfonylurea Drugs,” Nutrition & Metabolism (2011), doi: 10.1186/1743-7075-8-71