brain-2062057_640.jpg
31/Aug/2018

Multiple Sclerosis is a complex disease; those living with it need a simple approach. A treatment approach should appreciate the physiology of the disease process without neglecting the human body as a holistic system, and the patient as a person.

Naturopathy is an ideal philosophy of medicine for the treatment of M.S. as it aims to address disease processes and symptoms without loosing sight of the patient as an individual.

I chose to focus in neurological disease early into my professional career and as a result I have come across many complex chronic diseases of the nervous system including all subtypes of M.S. When patients come for their initial visit it is not uncommon to be privy to a long list of life events that have impacted the disease, symptoms that have evolved over years and medications that have been tried, stopped and tried again.

It’s easy to see why the practitioner on the other end of the patient with M.S. can become overwhelmed and confused, loosing sight of the big picture, dismissing the patients needs and goals. Unfortunately, this medical tunnel vision re-aimed at addressing each and every concern translates into complex and confusing treatment plans that most patients cannot comply with. I sympathize with these patients who have to remember to take dozens of pills while also dealing with a life altering condition.

To make matters worse, these confusing treatment plans hardly ever work because they tend to forget that the human body is not a series of islands, rather it’s a society striving to work in harmony and balance. The key to developing a simple, understandable and effective treatment plan is to figure out what is out of balance and how do we bring it back.

A typical treatment plan for M.S. has three parts: Foundations, The Immune System and Specific Symptoms. Since we are working toward bringing the body back into balance it is important to take the time to hear the full story and timeline of how the condition started and progressed. Often during the initial consultation it will become clear as to what type of events precluded the first attack and how these events triggered a physiological imbalance.

Diet therapy in multiple sclerosis

Foundations

It’s a futile effort to try and treat symptoms while the very basics of health and wellness are not fortified. The foundations of health can be summed up into three parts: Sleep, Diet and Exercise.

Sleep is the healing chamber for the body. Recently studies have shown that the brain undergoes a type of detoxification process while we sleep. Many neurodegenerative diseases have been correlated to poor sleeping habits. It is common to see sleeping issues in patients with M.S. In fact I have had a few cases where years of terrible sleep may have contributed to the patient experiencing their first symptoms related to M.S. This makes sense in the light of the new research demonstrating how important sleep is in clearing neurotoxic compounds from the brain.

One of the most important protocols I put together for my M.S. patients is aimed at improving sleep. This is achieved through sleep hygiene education and supplements that have been carefully vetted over my years in practices for their effectiveness in improving sleep initiation and maintenance.

Diet is important for a number of reasons, some are general and some are specific to M.S. The food we eat and its relation to our digestive tract determines our nutritional robustness.

M.S. is a chronic neuro-inflammatory state and therefore patients with M.S. will be using up vitamins and minerals involved in inflammatory processes at a greater rate than in a healthy control group. Therefor it’s important to determine what the nutritional status is of the M.S. patient (through consultation and specific lab tests), bring it back into balance and correct deficiencies. Otherwise the body will be unable to cope with the inflammatory process and the disease will progress.

It is also important to identify any food allergens, intolerances and sensitivities in the M.S. patient for these will perpetuate the inflammation. Chronic inflammation has a detrimental effect on the immune system, which I will discuss further in the next part of the treatment plan.

Another aspect related to diet is the health of the gastrointestinal tract and more specifically the micro-biome (the bacteria of the gut). A healthy micro-biome is important for detoxification, nutrient absorption and immune system regulation. A protocol addressing diet will focus on testing for nutritional deficiencies, food sensitivities, specific dietary guidelines for M.S. and supportive supplements where necessary.

A good dietary resource specific to M.S. is The Wahls Protocol.

physiotherapy for Multiple SclerosisExercise is a powerful health modulator and is under-appreciated for its importance in chronic disease and specifically M.S. Often exercise comes in the form of physiotherapy in progressive M.S. and the first thing I will do with a patient is set them up with one of the physiotherapists in my clinic (if they don’t already have a physiotherapy program). Often patients newly diagnosed with M.S. are neglected by the medical system in terms of exercise. In-patient rehab programs are inadequate, scooters and wheelchairs are promoted over therapy. Exercise and physiotherapy are instrumental in promoting neuroplasticity, decreasing inflammation, improving energy metabolism, maintaining and improving upon range of motion.

My clinic specializes in neurological rehabilitation using the Bobath Physiotherapy approach. Physio-Logic

The Immune System

Multiple Sclerosis is an autoimmune condition and therefore one cannot overlook the role of the immune system. Autoimmunity basically translates to a confused immune system that has targeted healthy cells and tissues rather than disease. The philosophy behind this part of the treatment plan addresses two questions: how the immune system became confused and how to bring it back into harmony.

There are many theories as to the cause of M.S., to name a few: Genetics, Vitamin D deficiency, Environmental Toxin Exposure, Candida Overgrowth, Dairy Protein Antigen Confusion and Leaky Gut Syndrome. There are truths to be told within many of these theories but in reality we just don’t know exactly what causes M.S. Some things we do know are the triggers for symptom activation, and things that reduce the risk of developing M.S. We know that stress (physical and/or emotional) often precipitate symptom relapse and progression. We also know that having adequate vitamin D levels are protective toward the development of M.S.

Vitamin D from SunlightVitamin D is not longer thought of as merely a bone-building vitamin. In reality it is more of a hormone and has a very important role in maintaining the health of the immune system. Step one of addressing the immune system is making sure the patient has optimal levels of vitamin D and if not, to adjust those levels using specific supplemental doses of vitamin D along with calcium and regular follow-up blood work.

Stress, whether it physical or emotional, causes a burden on the body. Most of the time we are able to cope with short durations of stress; however, when the stressful event is severe enough or lasts long enough it can impact the immune system in a negative way. Chronic stress can affect the immune system in two ways: Creating chronic inflammation that harms tissues and suppressing immune cells needed to fight infection.

When the immune system is under prolonged stress it becomes tired and makes mistakes, much like how we feel when under stress. One of these possible mistakes is mounting an autoimmune attack, harming normal healthy tissue rather than disease. Prolonged stress also depletes natural anti-inflammatory compounds like cortisol, allowing inflammation to run amuck. Therefore the protocol built around the immune system is aimed at decreasing stress on the immune system and bringing the immune system back into balance.

Anything that can be causing unnecessary inflammation needs to be dealt with and therefore chronic infections and food sensitivities must be addressed. Specific lab testing is used to investigate infections and sensitivities. Common food sensitivities in M.S. patients include: Dairy, Gluten, Yeast and Egg.

Once the major obstacles to a healthy immune system are removed we can work toward assisting the immune system back into a balanced state. The most important cells involved in bringing the immune system back into balance are “regulatory T cells” also known as “T suppressor cells”. These cells maintain tolerance in the immune system preventing autoimmunity. Part of the protocol is therefore aimed at supporting these cells. Some compounds that influence regulatory T cells are: probiotics, vitamin D, vitamin A, Omega 3 fatty acids and food sensitivities.

Sleep

Specific Symptoms

Treating foundations and immune system irregularities take time, therefore it is almost equally important to address the specific symptoms of the patient. Fatigue, weakness and pain are often obstacles to important foundational concerns like sleep and exercise.

Fortunately, there are many great strategies within Naturopathic medicine to help address the most common symptoms in M.S. namely: Weakness, Spasticity, Fatigue, Pain, Bowel and Bladder issues. There are dozens of supplements that have shown promise in treating the common symptoms of M.S. The art of the practitioner is in choosing the right compounds for the right patient. As an example, medical marijuana can be very effective for spasticity, pain, bladder dysfunction and sleep but can exacerbate weakness. A good practitioner with experience in treating M.S. will know how to choose the appropriate medications for the patients needs.

Multiple Sclerosis is a complex condition with many subtypes and many different ways it affects the individual patient. Naturopathic medicine aims to treat the root cause of disease while also addressing the individual concerns of the patient. The treatment plan can be summed up into three areas: Foundations, Immune System and Specific Symptoms. This helps direct the practitioner toward the right approach and simplifies the philosophy behind the treatment, improving upon compliance and therefore patient outcomes.

[button size=”btn-large” link=”https://doctorshawn.ca/contact-us/” target=”_blank” ]Call us today![/button]


boys-286245_640.jpg
09/Aug/2018

Do you give your kids probiotics?

Every year it seems like the back to school commercials start to pop up earlier and

earlier in the summer months. Although these commercials are aimed at bringing

parents into office supply and clothing stores in prep for their kids returning to

school, as parents we can also use this time to implement nutritional strategies to

help our kids excel during the school year.

Besides the obvious beneficial lifestyle approaches like eating a balanced nutrient

rich diet and daily exercise, there are a few specific recommendations that may help

your kids have the edge when it comes to starting school.

Probiotics Kids Back to School

[banner ]Probiotics[/banner]

Probiotics are live bacteria cultures that seem to have varying health benefits when

introduced into our gastrointestinal tract. Probiotics are naturally found in many

fermented foods such as yogurt, kefir, miso, tempeh, sauerkraut and kombucha. It is

believed that as a species, fermented foods played a larger role in our diet as we

evolved and our bodies have grown to rely on these bacterial cultures for optimal

health and wellbeing. Our modern “western” diet has been relatively low in these

fermented foods and there have been hypothesis relating many chronic diseases of

the gastrointestinal tract and immune system back to imbalanced gut bacteria.

Subsequently we have witnessed a surge in probiotics being offered in supplemental

form as a way to help restore this balance. It is important that I stress the fact that

probiotics alone are not the complete picture with regard to a healthy

gastrointestinal and immune system but research has suggested that they do play a

part.

 

Probiotics help boost the immune system – with kids heading back indoors and

spending large amounts of time in classrooms with each other (including daycare),

there is a dramatic increase in germ exposure and potential for kids to fall prey to

illness. In one study, 326 children aged 3-5 years were randomly assigned to

receive, in double-blind fashion, probiotic supplementation. Treatments were given

twice per day in divided doses for 6 months, including the winter season. Compared

with placebo, the probiotic group had the following results; fever reduction 53-73%,

cough reduction 41-62%, decreased runny nose 28-59%, decreased need for

antibiotics 68-82%, reduced absence from school 28-32%.

 

Probiotics help with allergies – Heading back indoors can trigger many kids who

are especially allergic to dusts and molds. With regard to asthmatic children with

allergic rhinitis, studies have shown the use of probiotics resulted in a significant

reduction in the inflammatory immune chemistry produced by peripheral blood

mononuclear cells. Further studies have shown specific down-regulation of T cells

(immune cells), which beneficially alter the balance of pollen specific antibodies in

seasonal allergic rhinitis. In short – probiotics lower the allergic load and decrease

inflammation.

 

Probiotics help with mood – Recent research is showing new gut-brain

connections as happy gut ecology seems to make for happier brains. In one

particular study, anxious mice dosed with probiotics showed lower levels of anxiety,

decreased stress hormones, and even increased brain receptors for

neurotransmitters vital in curbing worry, anxiety and fear. With better mood comes

greater ease and ability to learn in school settings and beyond.

Stay tuned for part 2 which will focus on cold/flu prevention and treatment.

Book a consultation with our Naturopathic Doctor Shawn Meirovici for

more information on child-friendly probiotic strains and dosages.

[button size=”btn-large” link=”https://doctorshawn.ca/contact-us/” target=”_blank” ]Book Now[/button]

Leyer, GJ et al. Probiotic effects on cold and influenza-like symptom incidence

and duration in children. Pediatrics 2009; 124-179.

Walker, WA. Mechanisms of action of probiotics. Clin Infect Dis. 2008; 46 (Suppl

2): S87-91.

Yang, G et al. Treatment of Allergic Rhinitis with Probiotics: An alternative

approach. N Am J Med Sci. Aug 2013; 5 (8): 465-68.

Javier, AB, Forsytthe, P & Cryan, J. Ingestion of Lactobacillus strain regulates

emotional behavior and central GABA receptor expression in mice via the vagus

nerve. Proc Natl Acad Sci USA. Sep 20, 2011; 108(38): 16050-55.


brothers-457237_640.jpg
06/Jul/2018

One goal of Naturopathic pediatrics is to use natural therapies to prevent and treat mild to moderate conditions, resorting to pharmaceutical and surgical interventions as secondary options or in emergency situations. The core belief in Naturopathic pediatrics is to encourage the body to heal itself. This is achieved through supporting the immune system, addressing nutritional deficiencies, promoting a healthy diet and lifestyle; including exercise, sleep and mental habits.

 

Disease as a Process

Fever is an excellent example of how a naturopathic approach may differ from a conventional approach. A fever is our natural defence mechanism against a pathogen. By raising the temperature of the body a few degrees many pathogens (viruses, bacteria) stop functioning optimally and the body activates inflammatory immune cells and enzymes to destroy the invading organism. While conventional medicine often sees disease symptoms, like a fever, as something to be suppressed, naturopathic doctors often see them as something to be promoted.

It has become commonplace to try to intervene in the disease process too swiftly, taking medications to decrease fever and inflammation prematurely. The Naturopathic Doctors role is to recognize the stages of the disease process, closely monitoring a fever, knowing when a fever should be left alone and when intervention is necessary. All the while helping the child feel better without interfering in the healing process.

There are generally 5 stages of the disease process: Incubation, Aggravation, Destruction, Abatement and Reconstruction.

Incubation is where the invading organism is accumulating in certain areas of the body. This process can take hours to days to weeks to months. The immune system reacts and either removes the organism or the organism replicates too quickly and the body moves to the next stage. It is common to not have any obvious signs of infection during this stage.

Aggravation includes the usual signs of inflammation, replication of immune cells, fever, redness, pain, malaise, loss of appetite and fatigue. These are signs that the immune system is hard at work and should be encouraged. This is where suppression commonly occurs with fever reducing medications, and anti-inflammatories, which can revert healing back to the incubation phase.

Destruction is the peak of inflammation and results in the destruction of one organism or another.

Abatement occurs when the fight is over and it’s time to clean up the debris. The immune cells, dead organisms and inflammatory fluids must be removed by the body. The fever “breaks” and sweating begins. Coughing up phlegm, runny nose, diarrhea and other discharges remove the debris from the body. In conventional medicine, cleanup is often viewed as an additional set of annoying symptoms that need to be suppressed by drugs, often impeding on the “cleanup” process.

Fever reductions after administering fever reducing medications should not be confused with abatement. The fever will often spike again. The immune system is trying to do its job but is being suppressed.

Reconstruction happens next. The body is reconstructing damaged tissue, the body is attempting to reset back to its original state.

Most pediatric infections will run their course, and the child will heal themselves. The Naturopathic Doctor watches the disease process closely, waiting to see if the body will heal or get worse requiring intervention. Besides making this decision, it is also the Naturopathic Doctors role to encourage processes like fevers, rather than suppress healing and teach parents to save fever reducing medications until necessary.

Intervention

The Naturopathic Doctor monitors the inflammatory process, only intervening to prevent a severe state of aggravation. Mild interventions such as cooling baths, friction rubs, warming socks can often lower a high fever and help the child feel better. These therapies have their limits and are not always sufficient. It is also the Naturopathic Doctors role to recognize an emergency situation that requires pharmaceutical intervention and to educate the family with regard to monitoring the disease and recognizing an emergency situation.

Safety

The first principle of Naturopathic Medicine is “primum non nocere” first, do no harm. Safety is a combination of good diagnostics, good choice of treatments, prevention, and physician intervention when necessary. The properly trained, properly regulated Naturopathic Doctor should be able to guide the family through a confusing landscape of both conventional and non-conventional medicine by knowing which “alternative” approaches are safe and effective and when referral to another integrative professional or physician will be in the best interest of the infant, child or adult.

 

Dr. Shawn is now at KidCrew Fridays from 10am-6pm



couple-walking-1245848.jpg
18/Apr/2018

A Naturopathic Doctor can play an important role in managing CMT through dietary counseling, specialized testing and by offering relevant integrative therapies.

CMT is a hereditary disorder affecting the motor and sensory nerves.  It’s characterized by progressive loss of muscle tissue and sensation in various parts of the body. Currently CMT is incurable and is the most common inherited neurological disorder and affects approximately 1 in 2,500 people.

In terms of managing CMT, by far the most important goal is to maintain movement, muscle strength and flexibility. Often overlooked is the role diet, pain management and antispasmodics can play in CMT. Having a naturopathic doctor familiar with neurological conditions can be a valuable part of a healthcare team.

 

Sugar

Although sugar is sweet and delicious, at high concentrations it can become a poison for the nervous system. Uncontrolled blood sugar, including diabetes, will exacerbate nerve damage and peripheral neuropathy in CMT. A naturopathic doctor can test blood sugar in order to determine if it poses a risk. Dietary counseling, such as education around glycemic index and glycemic load, can help balance blood sugar levels. There are also effective strategies that can boost insulin sensitivity thus lowering blood sugar. These include; low impact exercise and supplements like chromium, berberine, agaricus mushroom, american ginseng, and vitamin B3.

 

Diet

A diet rich in antioxidants and anti-inflammatory compounds can greatly improve neuromotor and locomotor performance. Curcumin and vitamin C are two natural compounds that have been and are currently being investigated as potential therapeutic agents for CMT. One study demonstrated a decrease in neuron death and an increase in size and number of nerve sheath cells after administration of curcumin. Intermittent fasting is a diet strategy that promotes a 16 hour fasting period each day and has been shown to improve locomotor functioning in CMT patients after 5-months.

 

Nerve Pain

Nerve pain and neuropathy can be addressed through a few different approaches. Application of topical counterirritants such as capsaicin and menthol can work by overriding pain signals. Peripheral pain blockers work by re-routing pain signals locally at the source of the pain. Effective peripheral pain blockers include: acupuncture, electro-acupuncture, moxabustion and transcutaneous electrical nerve stimulation (TENS).  Central pain blockers block or override pain signals where they are interpreted, in the brain. Central pain blockers include cannabis, wild lettuce and california poppy.

 

Cramps and Spasms

There are many effective integrative therapies for cramps and muscle spasms. These therapies work by balancing electrical conduction at the muscle and stimulating inhibitory neurotransmitters. Some of the most effective therapies are: magnesium, acupuncture, GABA, valerian, cramp bark, skullcap, passionflower and cannabis.

 

Nerve-Protection

One of the largest areas a naturopathic doctor can serve as a crucial part of the integrative healthcare team is in offering strategies to prevent further nerve damage, and in some cases reversing existing nerve damage. Neuroprotectants generally belong to two main categories: antioxidants and anti-inflammatories. Neuroprotectant antioxidants include: alpha lipoic acid, glutathione, resveratrol, EGCG, flavonoids, Co-Q10, CBD and THC. Anti-inflammatory strategies include testing for food sensitivities, hormone levels and environmental toxins.  Anti-inflammatory supplements include Omega 3 fatty acids, curcumin, boswelia, and CBD.


IF-268x300-1.jpg
12/Sep/2017

Intermittent fasting is a different way of thinking about eating.

I’m suggesting that the majority of people have been eating too much and too often. I’m suggesting that breakfast is not the most important meal of the day. By following a few simple guidelines my readers can  loose weight, feel great and be healthier than ever before. The guidelines are:

 

  1. “6 to 8 and feel great”
  2. “Eat what you need”
  3. “Respect your food, respect yourself”

 

6 to 8 and feel great

Everyday eat within a 6 to 8 hour time frame. If you eat breakfast at 7:00am then your last meal of the day should not be later than 3:00pm. If you eat lunch at 12:00pm then your next and last meal should be no later than 8:00pm. In the first scenario you are basically skipping dinner and in the second scenario you are skipping breakfast. Water, tea, and even coffee are allowed outside of the 6-8 hour allotted time frame as long as there is no added calories, i.e. sugar, milk and or cream. There is also no snacking outside of your 6-8 hour window.

Now let me tell you why and how intermittent fasting works. Immediately after eating, a hormone in your body called insulin rises. Insulin tells your body to burn carbohydrates (sugar) for energy and to store whatever hasn’t been used in your liver and fat cells. This process continues for approximately 4 hours after eating. After 4 hours insulin drops and your body begins to dip into stored sugar and fat reserves for energy; or in other words that’s when you start burning fat.

It’s common practice for most people to eat 3 times a day with snacks in between, this means that we almost never dip into our fat stores. Therefore you would have to do some intensive daily exercise or eat incredibly small portions to loose weight. By following the 6-8 rule; you can almost be certain that you will be burning fat for approximately 10-12 hours per day. The only thing keeping you from shedding excess pounds is by being excessive with portion size and calorie intake, which brings us to the next guideline “eat what you need”.

 

Eat what you need

This guideline basically translates to portion control. One advantage about using the 6-8 methodology is that you will start becoming more in tune with your body and more aware of hunger and satiety. It is a great feeling to eat when you are actually hungry rather than out of habit. When we experience hunger, food is digested better. Hunger causes your gastrointestinal tract to prepare for food, including ample amounts of stomach acid aiding in the proper breakdown and absorption of nutrients.

Pay close attention to the point at which you no longer feel hunger and you are adequately satiated. Do not overeat. Eat to a point that you feel satisfied but not heavy and bloated.  You may notice that portion sizes become smaller. Now, because we are eating only two meals per day, it is also important that when we eat, we eat nutritious food and a variety of foods. Which brings us to the next guideline.

Respect your food; respect yourself

This guideline is about what kind of food you eat and how you eat it. As mentioned in the previous section, since we are essentially eating only twice per day, we want to be putting high quality foods into our body. Fresh, local and organic foods are what you want to focus on. The great thing about this diet is that it there are no restrictions on foods, it’s more about quality. Try to have meals that have a good quality protein, and complex carbohydrates such as veggies and whole-grains.

While making healthy choices is very important, it is also just as important not to stress over your food. Do your best to cook healthy while acknowledging that sometimes you will find yourself eating out, ordering fast food, and having desserts. Don’t beat yourself up about the choices you make, love whatever it is your eating, own it and do your best to eat healthy most of the time. Love your food and love yourself.

 

Final Thoughts

The guidelines I have purposed, although expressed in an original way, are not new concepts. Eating within a 6-8 hour window is also known as intermittent fasting; a lifestyle and medical intervention that shown to have a multitude of health benefits including lowering blood pressure, staving off cardiovascular disease and improving longevity. Presenting these ideas in away that is easy to incorporate into a daily routine can help to improve the lives of many people. I encourage you to try it out, give it a few weeks and let me know how you feel.

Fitness trainer Mike O’Donnell (2 meal mike) does a great job of further explaining intermittent fasting and how to easily incorporate it into your daily routine. I encourage you to visit his site http://www.theiflife.com


DSCF2585.jpg
02/Mar/2016

There are few fruits more enticing than the jewel-like arils (seed casings) of pomegranate. Adding to the allure of pomegranate are its incredibly versatile culinary applications and its amazingly powerful medicinal properties.

The fruit we know as Pomegranate comes from the deciduous shrub Punica Granatrum. The Pomegranate is native to Iran, The Himalayas and Northern India. An ancient fruit mentioned as early as Iron-Age Greek Mythology; pomegranate is now cultivated in many warm and dry climates around the world. In the northern hemisphere the fruit is typically in season from September to February. There are many culinary uses for pomegranate. The sweet and sour juice has long been a popular drink in Persian and Indian cuisine and has recently become familiar to consumers in Canada and the United States. The cocktail mixer, Grenadine, is a syrup made from sweetened and thickened pomegranate juice. Pomegranate can also be used to create delicious sauces. For instance, in the traditional Iranian recipe, Fesenjan, a thick sauce is made from pomegranate juice and ground walnuts. Pomegranate arils are also great to eat on their own. After opening up the pomegranate, try separating the arils from the pulp in a bowl of water. The pulp will float while the arils sink to the bottom of the bowl.

Pomegranate is an important traditional remedy in many ancient systems of medicine. In Ayurvedic medicine the rind of the fruit is used against diarrhea, dysentery and intestinal parasites. It is now known that the rind contains ellagitannins that are anti-parasitic, anti-inflammatory and astringent (helping to stop diarrhea). The medicinal applications of pomegranate that ancient medical systems have known about for centuries through empirical evidence is now being validated through scientific investigation.

Recently a multitude of studies has surfaced outlining pomegranates therapeutic application in areas such as: cancer therapy, cosmetics, rheumatology and cardiology. The following is a summary of some of the most recent research on pomegranates application in these medical topics.

In 2009 the journal “Nutrition and Cancer” published a review on cancer chemoprevention by pomegranate. In the review the authors outline recent research showing that pomegranate polyphenol extracts selectively inhibit the growth of breast, colon and lung cancer cells in culture. The review also demonstrated that in pre-clinical animal studies, oral consumption of pomegranate extract inhibited the growth of lung, skin, colon and prostate tumors. As far as human trials go, an initial phase 2 clinical trial of pomegranate juice consumption in patients with prostate cancer reported significant prolongation of prostate specific antigen (PSA) doubling time. This means that the pathological growth and disruption of normal functioning prostate tissue was likely decreased. PSA doubling time can be a useful tool in the screening and monitoring of prostate pathology in men, but has to be interpreted in the correct context and by a trained health care professional.

An excellent article was recently published on the topic of PSA in the November 2010 issue of Naturopathic Doctors News and Review (ndnr). Research would suggest that pomegranate has potential application in the field of natural cosmetics. A study in the “International Journal of Dermatology” demonstrated that a polyphenol extract of the rind fruit and seed of pomegranate protected skin cells against UV-B radiation induced skin damage and increased the synthesis of collagen. Collagen is a connective tissue closely related to cartilage; the shock absorbing cushion found in joints. Interestingly, a recent study in the journal of “Arthritis Research and Therapy”demonstrated that pomegranate extract has the ability to inhibit chemical messengers involved in the breakdown of cartilage, as well as decreasing inflammation often seen in osteoarthritic joints.

Since ancient times, Pomegranate has been known as a tonic for the cardiovascular system. I often prescribe a glass of pomegranate juice per day as adjunctive treatment for high blood pressure. The rich red color of pomegranate juice suggests that it is high in polyphenol rich antioxidants. There is great concern in patients at risk for cardiovascular disease for the development of atheroscelrotic plaques. In summary, atheroscleortic plaques develop when lipoprotein (fat transporting protein) becomes oxidized by free radicals and are subsequently attacked by the immune system. The combination of oxidized lipoproteins and immune cells create pimple-like outgrowths in the artery wall, blocking blood flow. LDL-cholesterol (often referred to as bad cholesterol) is not bad in of itself, it is the action of free radical damage on LDL-cholesterol that makes for trouble. Antioxidant-like molecules produced by the body such as PON1 and PON2 protect against atherosclerotic development. A study in the England journal “Biofactors” demonstrated that the polyphenols in pomegranate juice increase the production of PON1 and PON2 therefore helping to decrease the risk of forming atherosclerotic plaques. These studies suggest that molecules called polyphenols found in pomegranate juice, rind and seed have multiple benefits on health. It is our luck that pomegranate arils and juice are delicious and can be easily incorporated into the diet. Unfortunately it is impossible to know exactly how rich the polyphenol content is in the pomegranate or pomegranate juice you buy. However, a good rule of thumb to ensure that you get a good dose of polyphenols is to pick fresh, brightly colored, organic if possible; pomegranates. When buying juice, make sure that it is 100% pure pomegranate juice. A great website on how to pick and prepare pomegranate is www.pomegranatefruit.org


chlorella-pills-1-1244389-639x426-1.jpg
21/Nov/2015

In this months edition we shift gears slightly to focus on a “super-food” most commonly found in the form of a dietary supplement; Spirulina.

Spirulina is a cyanobacteria; meaning that it’s a bacterium which derives its energy through photosynthesis. Cyanobacteria are also commonly known as blue-green algae. Spirulina is commonly made from two strains of cyanobacteria: Arthrospira platensis and Arthrospira maxima. Although now cultivated around the world, spirulina is found naturally growing in only three lakes: Lake Chenghai (China), Lake Chad (Africa) and Lake Texcoco (Mexico).

Spirulina is available at most health food stores in the form of powder, flake or tablet. Much like Quinoa, Spirulina is a complete protein source, containing all essential amino acids. It is also a source of essential fatty acids and is one of the only vegan friendly reservoirs of the omega-3 fatty acids EPA and DHA. Spirullina’s blue-green pigment is an indicator that it is rich in vitamins and other beneficial anti-oxidants. These antioxidants include, but are not limited to: beta-carotene, zeaxanthin, and chlorophyll. The unique blend of antioxidants found in spirulina make it a fascinating health promoting supplement, which has demonstrated benefit in the treatment of HIV, brain health, heavy metal chelation, cardiovascular disease and allergies.

The Journal of Nutritional Science and Vitaminolgy published a paper that investigated the effect of supplementing rats prone to the development of cognitive disease , similar to Alzheimer’s disease, with spirulina. Alzheimer’s disease is characterized by the deposition of amyloid beta-protein, which is thought to “gum up” the functioning of neurons in the brain. The rats studied were bred to be prone to the deposition of amyloid beta-protein. One group of rats received daily supplementation of 50mg/kg spirulina, another group received 200mg/kg spirulina and the third group did not receive spirulina. Analysis of the rat brains (poor rats) demonstrated a reduction in amyloid beta-protein in both spirulina treated groups. There were also lower levels of oxidative damage in the brains of spirulina treated rats. Therefore spirulina may be a beneficial supplement for the prevention of Alzheimer’s disease in genetically prone individuals.

Back in 1998 a paper was published that investigated the effect of spirulina extract on the growth of HIV in human white blood cells. It was found that extract concentrations ranging between 0.3-1.2 micrograms/ml reduced the growth of HIV by 50%. The authors concluded that spirulina may be a potential agent used for the treatment of retroviruses like HIV.

Aside from a runny nose, itchy eyes and sneezing, seasonal allergies are characterized by a relative increase in white blood cells known as TH2 cells. One of the ways TH2 cells increase and cause allergy is by a messenger molecule in the blood called interleukin 4 (IL4). In 2005 the Journal of medicinal food published a study that looked at the blood of individuals with allergic rhinitis before and after supplementing with spirulina. The study was a placebo controlled randomized crossover trial where individuals either received 1g, 2g spirulina or placebo daily for 12 weeks. The blood samples at 12 weeks found that 2g spirulina per day reduced IL4 levels by 32%.

Environmental medicine is an exciting emerging field of medicine that looks at how toxins in our environment effect our health, and more importantly how to protect ourselves from the harmful effects of environmental toxins. There are few natural substances that have demonstrated an ability to promote the excretion of some of these harmful toxins, spirulina is one of them. A study published in 2006 looked at the effect of a spirulina and zinc supplement on individuals in Bangladesh chronically exposed to the toxic metal arsenic. These individuals were given 250mg spirulina extract and 2mg zinc twice daily for 16 weeks. There was a increase in urinary excretion of arsenic (detoxification) at 4 weeks which continued for an additional 2 weeks in individuals taking the spirulina zinc combo. At 16 weeks the spirulina plus zinc combo removed 47.1% arsenic from scalp hair (one of the ways to test for arsenic exposure is through hair analysis), whereas results from placebo were not statistically significant. Other studies have shown that spirulina may also chelate (remove) iron, which can be useful for individuals with toxic amounts of iron in the body but may be counter productive for individuals taking an iron supplement.

It seems that a large part of the health benefits seen through the use of spirulina are due to its unique blend of antioxidants. A laboratory study discovered that cells exposed to harmful chemicals had 4-5 times less apoptosis (cell death) when treated with an aqueous extract of spirulina. Another study demonstrated that a diet supplemented with 0.1% spirulina protects against inflammation and oxidative damage in brain neuronal cells. This same studied showed that spirulina increased the proliferation of neural stem cells which have the ability to replace damaged cells. Spirulina is therefore a promising natural supplement for the field of neural and cognitive health.

A study published in the november 2007 edition of the journal: Lipids in Health and Disease, investigated the effect of spirulina supplementation on cholesterol and blood pressure. Thirty six men and women had blood cholesterol levels and blood pressure measured before the study. They were supplied with 4.5g/day spirulina for 6 weeks. There were no other changes to diet and exercise. After 6 weeks total cholesterol levels decreased by approximately 20 mg/dl, tracylglycerides decreased by approximately 60 mg/dl and HDL (good cholesterol) increased by approximately 10 mg/dl. Systolic and diastolic blood pressure also decreased in participants by approximately 10 mmHg. With all the health promoting benefits of spirulina, it is important to consider a few things before taking this medication. As with every supplement, allergy can occur so be careful to monitor and possible allergic symptoms when taking spirulina for the first time. Spirulina contains the amino acid phenylalanine, which can be harmful for individuals who cannot metabolize this amino acid known as phenylketonuria. Since spirulina is a water born blue-green algae it is important that it is not sourced from a contaminated water source. I would recommend going with a reputable supplement company. Spirulina is a very promising natural dietary supplement whose beneficial effects can be seen in almost every organ system in the body. These effects are likely due to its unique blend of antioxidants. Use this supplement with necessary caution and remember that in nature there exist both beneficial bacteria and harmful bacteria, a naturopathic doctor can help to explain the difference and point you in the right direction toward optimal health.


tea-1327515-1279x1183-1.jpg
03/Nov/2015

Like a fine wine, Pu-erh is a variety of tea that is often better with age. Pu-erh is a post-fermentation tea, typically produced in the Yunnan province of China. The tea derives its name from Pu-er county in Yunnan, where trading of this fermented tea took place during imperial China. Pu-erh tea begins it’s life much like green tea but undergoes the process of pressing (compacting the tea into round or brick-like shapes) and then fermentation. Raw Pu-erh has not been artificially fermented and therefore must be aged for several years allowing bacteria and fungi to slowly act of the tea leaf breaking down and transmuting many of the compounds and enzymes in the tea. Ripened Pu-erh is a relatively recent invention where the tea leaf undergoes special processing to mimic aged Raw Pu-erh. Moisture, heat and rotation are some of the conditions employed on the tea in order to accelerate the process of fermentation. A good Pu-erh requires the right amount of aging and the right strains of bacteria and fungi for fermentation. The taste is distinctively earthy with many subtleties.

Much like wine, Pu-erh tea ranges in its quality and vintage. Pu-erh can range from 3-months to 100 years old. Most enthusiasts will agree that the very young or the very old Pu-erh is the best, the middle years are sometimes referred to as “awkward”. Usually a raw Pu-erh will start to develop it’s mature taste after 5 years of aging. Buying Pu-erh can be difficult for the westerner as most authentic Pu-erh (must come from Yunnan to be considered authentic Pu-erh) has little to no english on the package. The best way to ensure that you are getting the quality you’re interested in is to develop a relationship with a tea distributer or manufacturer who is knowledgeable on the subject. There is a Pu-erh out there for every palate and every pocketbook.

Pu-erh tea has been a favourite of monks and is a common ingredient of many health promoting elixirs in China. The fermentation process endows this tea with slightly different compounds than green or black tea and therefore deserves its own scientific investigation. When tea undergoes fermentation, such as is the case with Pu-erh, some health promoting compounds are lost (such as catechin antioxidants); however, others are gained. Recent research has revealed that the concentration of gallic acid (an anti-microbial), a compound called theabrownin, various polysaccharides and enzymes are increased in fermented tea.

Scientific studies performed in the last decade have demonstrated Pu-erh tea to have antimicrobial, fat busting and cholesterol reducing properties. The Journal of Agricultural Food Chemistry published a study demonstrating that a Pu-erh tea extract (PTE) had an antiviral effect on hepatitis B virus (HBV). The PTE had the ability to suppress the replication of virus DNA, while also exerting antioxidant effects inside cells affected by the virus. The researchers could not pinpoint the exact components that made PTE effective but conclude that it is likely due to a combination of compounds working together. The importance of this study is enhanced due to a small amount of substances currently available to treat HBV.

The journal Nutrition Research published a research paper in June of 2011 investigating the weight reducing effects of Pu-erh tea extract. 36 pre-obese Japanese adults were followed in a 12-week double blinded placebo controlled comparison study. The subjects ingested a barley tea with or without PTE (333mg) before each of three daily meals. The group taking PTE had a reduction in weight and body mass index (BMI) compared to the placebo group. The reductions in weight and body mass were only evident after 8-weeks on the PTE. Computed tomography demonstrated the the PTE group had a significant reduction in visceral fat after 12 weeks. There were no adverse reactions in the PTE treated group. The authors speculate that the weight reducing properties of PTE may be due to the high gallic acid content since prior research has demonstrated gallic acid to have anti-obese effects in animals.

Theabrownin (TB) is another compound found exclusively in Pu-erh tea that has recently been shown to have cholesterol and fat lowering properties. A study in 2010 demonstrated that increases in triglycerides, total cholesterol, LDL cholesterol and decreases in HDL cholesterol (also known as good cholesterol) were prevented in rats who were fed a high fat diet and supplemented with TB versus rats fed a high fat diet with no supplemental TB. The content of cholesterol and bile-acids found in the feces of the rats with supplemental TB was significantly higher than that of those rats with no supplemental TB. This suggests that TB could promote the transformation and excretion of dietary cholesterol. Therefore, TB and Pu-erh tea may be a promising supplement in the treatment of high cholesterol.

For centuries, Pu-erh tea has been touted as a great digestive aid. A scientific study in 2010 investigated the molecular composition of polysaccharides isolated from Pu-erh tea. Due to the fermentation process the content of water soluble polysaccharides was increased as well as the content of digestive enzymes including: cellulase, pectinase, and glucoamylase. In theory these enzymes may aid with the the digestion of certain foods when taken with a meal, thus reducing gas and bloating.

While all tea (Chamellia Sinensis) has health promoting qualities, different ways of preparing tea, endow it with slightly different properties. Recent research suggests that the fermentation process that Pu-erh tea undergoes gives this tea a slightly higher complement of gallic acid, polysaccharides and hydrolase enzymes. These compounds have been demonstrated to be useful in weight reduction, intestinal gas reduction and as an antimicrobial. There are no reported adverse effects with drinking this tea aside from those associated with caffeine intake. If you choose to age Pu-erh yourself, many experts recommend a clay pot (to allow the tea to breathe) and to store in a cool dry place away from other odours (as tea will take on odour it is exposed to). If in a compacted form, the tea can be broken up with a knife “called activating the tea” if stored for short term but should be kept in compacted form if storing for over 5 years. The consumption and collection of Pu-erh can quickly become a healthy hobby.


autumn-2905_1280.jpg
28/Sep/2015

Pumpkin is a gourd-like squash of the Cucurbitaceae family. The origin of the pumpkin is not definitively known although it is thought to have originated in North America. Pumpkin is a very versatile food; almost every part of the vegetable is edible (shell, seeds, pulp, leaves, flowers). Although the taste and uses of pumpkin as a food may be common knowledge, especially around this time of year, the medicinal properties of pumpkin can often be overlooked.

The color of pumpkin can be attributed to the pigmented carotenoids beta and alpha carotene, the latter of which generates vitamin A in our body. Pumpkin also contains lutein making it an excellent menu choice to maintain eye health. Pumpkin seeds are often roasted and make an excellent snack in the fall and wintertime. Pumpkin seeds have many health benefits, which include a good source of zinc, tryptophan, magnesium, manganese, phosphorous and phytosterols. These nutrients help to promote immune system, cardiovascular, and reproductive health.

Diabetes

There have been several studies over the past decade investigating the effect of extracts of pumpkin on diabetes. One of the most recent studies found that mice who were fed a pumpkin paste concentrate maintained a lower blood sugar level than the control group. The authors were able to isolate two compounds from the pumpkin paste (trigonelline and nicotinic acid) which seem to have an ability to regulate enzymes involved in triglyceride accumulation and the progression of diabetes.

Another study, looked at a major complication of diabetes; kidney damage, and whether pumpkin can be used to prevent its progression. This 2010 study in the journal of Food Chemical Toxicology used a mixture of flax and pumpkin seed in the diets of rats with alloxan-induced diabetes. The flax and pumpkin seed mixture was able to quench free radicals and increase the level of antioxidants in the blood of the diabetic rats. Furthermore, on kidney biopsy, rats fed the seed mixture had less glomerular hypertrophy and tubular dilatation, meaning healthier kidneys.

Prostate

The application for pumpkin seed oil in prostate health has been a popular topic of scientific investigation. A recent double blind placebo controlled trial investigated the efficacy of supplementation of pumpkin seed oil and saw palmetto oil in middle-aged Korean men with benign prostatic hypertrophy (BPH). The trial was performed over 1 year on 47 patients with BPH. The patients received either potato starch (320 mg/day), or pumpkin seed oil (320 mg/day), or saw palmetto oil (320 mg/day) or a mixture of both pumpkin seed and saw palmetto oil (320 mg/day). The groups taking pumpkin seed and saw palmetto oils all saw a decrease in symptoms and an increase in quality of life after 3 months. Serum prostate specific antigen (a laboratory marker of prostate pathology) was reduced in the group taking a mixture of pumpkin and saw palmetto oil after 3 months. Urinary output (which is obstructed in many cases of BPH) improved in both the group taking pumpkin seed oil and the group taking saw palmetto oil at 6 and 12 months respectively. The study concluded by saying that pumpkin seed oil and saw palmetto oil supplementation is clinically safe and may be used as an effective complementary therapy for BPH.

When ripe, pumpkin can be boiled, baked, steamed or roasted. It can be eaten mashed or as a base for soups, purees and pies. I hope that you now see a whole world of possibilities for this incredible orange vegetable. Pumpkins are lonely after Halloween, so take one home and experiment in the kitchen.

Links

Pumpkin may be a good addition to the plate for Diabetes. Be sure to include exercise into any successful type 2 diabetes treatment protocol.

Check out this article on Exercise and Diabetes 


dr_shawn

Patient focused integrative health care. Utilizing effective natural approaches designed to be used alone or to compliment conventional medical care.


Information

Address: 225 Duncan Mill Road Toronto, Ontario M3B3K9

Clinic: 416-490-8243

Fax: 416-490-9961

Mon-Sat 10am-3pm

Dr Shawn. All Rights Reserved. Developed by SEOGorillas