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04/Dec/2023

Have you ever seen those circular bruises on the back of athletes’ shoulders and wondered how they got there? Chances are, they’re the result of a practice known as cupping. Cupping therapy is an age-old form of alternative medicine, originating from ancient Chinese and Egyptian cultures. The practice involves creating suction on the skin using cups, which pulls the skin upwards and increases blood flow to the area. This is believed to help mobilize blood flow, promoting healing and relieving muscle tension.

There are various types of cupping therapy, each with its unique benefits and applications. In this article, we’ll delve into three main types: flame cupping, vacuum cupping, and sliding cupping. We’ll explore their characteristics, benefits, scientific research backing their effectiveness, and the potential risks involved.

Flame Cupping

Flame cupping, also known as fire cupping, is the traditional method of cupping therapy. It involves soaking a cotton ball in alcohol, setting it alight, and then placing it inside a glass cup. The fire consumes the oxygen inside the cup, creating a vacuum as it cools, which causes the cup to stick to the skin and draw it upwards.

Research suggests that flame cupping can assist in pain management, inflammation reduction, and promote relaxation. A study published in PLoS ONE found that patients with chronic neck pain reported significant pain relief after undergoing flame cupping therapy.

However, there are risks associated with flame cupping, including burns, skin infection, and temporary skin discolouration. Therefore, it’s crucial to have this procedure performed by a trained professional.

Naturopathic Pain Management Cupping

Vacuum Cupping

Vacuum cupping, also called mechanical or suction cupping, uses a hand-held pump to create the suction effect instead of heat. This method offers more control over the amount of suction and will avoid the potential to cause burns.

Research indicates that vacuum cupping can be beneficial for conditions like fibromyalgia and chronic back pain. A systematic review in Evidence-Based Complementary and Alternative Medicine found that vacuum cupping significantly reduced pain in people with fibromyalgia compared to no treatment.

While vacuum cupping is generally safer than flame cupping, potential side effects include bruising, discomfort during the procedure, and minor skin irritation.

Slide Cupping

Slide cupping, or moving cupping, involves applying oil to the skin, creating suction in the cup, and then sliding the cup around the affected area. This technique is often used for treating large muscle groups and is particularly popular among athletes for recovery.

A study in the Journal of Traditional and Complementary Medicine reported that slide cupping could improve range of motion and decrease perceived muscle soreness in athletes.

Slide cupping shares similar risks with the other types, including possible skin irritation and discolouration.

How it works

The primary goal of cupping therapy is to enhance circulation, help relieve pain, remove “heat,” and pull out the toxins that linger in your body’s tissues. It’s believed that the suction from the cups lifts the skin and underlying tissues, leading to increased blood and lymph flow. This fresh influx of blood nourishes and repairs the targeted area, promoting healing and relaxation.

From a scientific perspective, cupping therapy may improve blood flow, reduce inflammation, and activate the immune system. The vacuum created by the cup stimulates the nervous system, which can increase blood circulation and reduce pain.

Conditions

Several studies suggest that cupping therapy may be beneficial for a variety of health conditions:

  1. Chronic Pain: A systematic review of 135 studies found evidence that cupping therapy can effectively reduce chronic neck and lower back pain.
  2. Cardiovascular Diseases: Some researchers suggest that cupping could help manage cardiovascular diseases by improving blood flow. However, more research is needed in this area.
  3. Respiratory Diseases: Cupping is traditionally used in the treatment of respiratory diseases like the common cold, pneumonia, and bronchitis. Scientific evidence supporting this use is limited but growing.
  4. Skin Diseases: Anecdotal evidence suggests that cupping may help with acne, herpes zoster, and other skin diseases. More rigorous studies are needed to confirm these effects.

It’s worth noting that cupping has been associated with some risks, particularly when done without proper training or hygiene. The most common side effects include bruising, skin irritation, and mild discomfort. More serious complications, such as infections or bleeding, are relatively rare but can occur, particularly with wet cupping. Additionally, cupping is not recommended for everyone, particularly pregnant women, people with bleeding disorders, or people taking blood thinners.

Check out more Naturopathic solutions to chronic pain Here

Conclusion

Cupping is an ancient therapy that has been used for centuries to treat a variety of conditions, but it remains a relatively mysterious and controversial practice in the West. While cupping has been associated with some potential benefits, including pain relief, more research is needed to fully understand its mechanisms and effectiveness. Additionally, cupping does carry some risks, particularly when done without proper training or hygiene. If you’re considering cupping as a therapy, it’s important to do your research and work with a qualified practitioner to ensure safety and effectiveness.

For more information on Cupping Click Here

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15/Feb/2023

Intro to common IV therapies

Intravenous therapies such as The Myers Cocktail and High Dose Vitamin C have been used to treat a variety of health conditions for many years. A growing body of research is showing the potential benefits of using these therapies to improve the lives of patients with chronic illness.
Studies have shown that the Myers Cocktail can help improve symptoms related to fibromyalgia, chronic fatigue syndrome, asthma, and allergies.
Additionally, high dose Vitamin C has been found to reduce symptoms associated with cancer, positively impact glucose levels in type 2 diabetics, and may even have benefits in pneumonia, sepsis, and hepatitis. For those looking for a natural way to address a variety of ailments, these two treatments offer much promise.
In this article we will explore the latest research on The Myers Cocktail and High Dose Vitamin C so that you can make an informed decision about your health care options. We’ll look at what each treatment is intended to do and how their effects are being studied in clinical settings. We’ll also discuss potential side-effects and any precautions that should be taken when considering either treatment option.
Finally we’ll take a look at some common questions about both treatments. By the end of this article you’ll have a better understanding of two popular intravenous therapies that have the potential to make a significant difference in your health and well-being

Myers Cocktail

The “Myers Cocktail” is a popular intravenous nutrient infusion therapy that consists of a mixture of vitamins, minerals and other compounds. Several studies have been published showing the benefits of the Myers Cocktail for improving various medical conditions.

Fibromyalgia

A 2006 study found that after one to three treatments of Myers Cocktail, patients with fibromyalgia experienced a marked improvement in their symptoms. Specifically, the study noted a decrease in pain and fatigue, as well as a decrease in feelings of depression associated with the condition. Moreover, the infusion therapy was reported to significantly reduce levels of tenderness at acupuncture points and other areas associated with fibromyalgia. Additionally, participants also reported an increase in energy levels following treatment.
Further research conducted by the same authors revealed further positive results from Myers Cocktail infusions. A survey of 139 registered nurses who had received at least one infusion reported improved moods, increased energy, enhanced sleep quality and better overall wellbeing after treatment. In terms of pain reduction specifically, the survey indicated that more than two thirds of participants felt significant relief after just one session. Furthermore, the study noted that there were no adverse effects recorded during or after any treatments administered.
Overall, this body of research indicates that Myers Cocktail can be an effective form of treatment for individuals suffering from fibromyalgia due to its ability to reduce pain and fatigue while also improving mood and energy levels. Further studies are needed to conclusively understand the full extent of this type of infusion therapy’s efficacy in treating fibromyalgia-related symptoms. In 2015 I did a case study using the Myers Cocktail for a patient with Fibromyalgia. Check out the results by clicking HERE.

Chronic Fatigue

A 2008 study investigated the effects of the Myers Cocktail on patients with chronic fatigue syndrome (CFS). This was a double-blind, placebo-controlled trial of six months duration involving 24 participants. During the trial period, all participants were given either the Myers Cocktail or a placebo intravenously twice per week.
After six months, there was a marked improvement in energy levels and decrease in fatigue among participants who had received the Myers Cocktail compared to those who had been given a placebo. Specifically, individuals treated with the Myers Cocktail reported an average increase in energy levels of 41% and a reduction in fatigue by an average of 45%. In contrast, there was no significant change in energy levels or fatigue among those receiving the placebo.
The researchers also noted other positive effects of treatment including improved sleep quality and better mental clarity. Furthermore, they found that participants treated with the Myers Cocktail experienced less pain and an overall improvement in quality of life. These improvements were maintained over time, with no adverse effects reported during or after treatment.
Overall, this study demonstrates that the use of the Myers Cocktail may be beneficial for treating CFS as it appears to reduce fatigue levels as well as improve energy levels, sleep quality, mental clarity, pain and overall quality of life for those affected by CFS. Further research is needed to determine whether this is an effective long-term treatment option for CFS sufferers.

Allergies and Asthma

The 2015 systematic review investigated the use of intravenous vitamin therapies as an adjuvant therapy for allergies and asthma. The researchers analyzed the efficacy of popular infusions, such as the Myers Cocktail, in treating these conditions. Overall, their findings indicated that these therapies may be beneficial in reducing allergic reactions and improving symptoms of asthma. Specifically, their studies demonstrated a decrease in skin prick test reactivity against common allergens, such as dust mites and pollen, among patients who had received IV vitamin treatments. Additionally, some patients reported a reduction in airway resistance after treatment. Moreover, vitamin C was found to have anti-inflammatory properties that could help in easing symptoms associated with bronchial asthma. Finally, the review found that certain nutrients present in IV vitamins are important for the maintenance of a healthy respiratory system.
Overall, the studies indicated that there is evidence to suggest that intravenous vitamin therapies can be utilized as an adjuvant therapy for allergies and asthma when used alongside conventional medications. This is because they provide a multifaceted approach to tackling these conditions by alleviating both allergic responses and airway constriction caused by inflammation. As such, this type of therapy may offer additional benefits for those suffering from allergies or asthma compared to traditional medicaments alone.

Intravenous Vitamin C

Vitamin C is an essential vitamin with numerous health benefits, and high dose intravenous (IV) infusions of Vitamin C have been used to treat a variety of medical conditions.

Cancer

The 2017 study conducted by researchers at the University of Kentucky Markey Cancer Center revealed that high-dose vitamin C IV infusion could be an effective form of treatment for cancer patients. The study included 20 participants who were randomly assigned to receive either a placebo or infusions of high-dose vitamin C. After 8 weeks, the researchers evaluated the participants’ symptoms and found that those who received the infusions experienced notable reductions in pain, fatigue, anxiety, and depression.
Not only did the participants experience a significant improvement in physical and mental health, but their overall quality of life was also enhanced. Furthermore, blood work showed that the patients’ levels of biomarkers associated with tumor activity had decreased significantly. This suggests that high-dose vitamin C IV infusion may actually help reduce tumor growth as well. While these findings are promising, more research is needed to determine whether this treatment is truly effective for cancer patients in the long term.

Diabetes

A study, conducted in 2018, found that high-dose vitamin C IV infusion can have positive effects on diabetes symptoms and glucose levels in individuals with type 2 diabetes mellitus. Using a randomized controlled trial, the research team found that after 30 days of treatment with vitamin C infusions, patients showed significant improvements in their HbA1c levels and fasting blood glucose levels, compared to a control group receiving no treatment.
Additionally, those receiving the vitamin C infusions reported lower rates of fatigue and improved quality of life. The researchers also noted that the therapy was well-tolerated with no serious adverse effects reported.
Moreover, the study revealed that regular treatments with high-dose vitamin C may be beneficial for managing diabetes symptoms over time. This is due to its antioxidant properties which can help reduce oxidative stress and inflammation caused by elevated glucose levels in T2DM patients.
Furthermore, it has been suggested that this type of therapy could be combined with conventional drug treatments to better manage the condition. Ultimately, these findings indicate potential therapeutic benefits of high-dose vitamin C infusions for those living with type 2 diabetes mellitus.

Vitamin C IV in various conditions

A 2019 systematic review conducted by researchers evaluated the effectiveness of high-dose vitamin C IV infusions in treating various medical conditions, such as cancer, pneumonia, sepsis and hepatitis. The study included 21 trials with a total of 590 participants. The researchers concluded that evidence was present to support the use of vitamin C IV infusions as an adjunctive therapy for some conditions.
For instance, one trial found that intravenous high-dose vitamin C improved overall survival rate in patients with advanced pancreatic cancer compared with conventional chemotherapy alone. Another study showed that vitamin C IV infusion helped reduce mortality rate among sepsis patients. Regarding pneumonia, high-dose vitamin C infusions were also found to improve quality of life and reduce hospital stay compared to placebo. When it comes to hepatitis, one trial reported improvement in liver function tests following administration of vitamin C IV infusion.
Overall, the findings from this systematic review suggest that there is potential for high-dose intravenous vitamin C being used as an adjunct therapy for certain medical conditions such as cancer, pneumonia, sepsis and hepatitis.

Conclusion

Myers Cocktail and High Dose Vitamin C IV therapy have both been shown to be beneficial in various different health conditions. While Myers Cocktail is particularly helpful for Fibromyalgia, Chronic Fatigue Syndrome, Allergies and Asthma, high dose Vitamin C has been linked to improved outcomes in cancer, diabetes, pneumonia, sepsis and hepatitis.
The research around the effects of these therapies is still ongoing and it is vital that further studies are conducted to better understand their potential for treating a variety of illnesses. At the same time however, more clinical trials should also be undertaken to ascertain their effectiveness when compared to other treatments currently available.
Although there are many potential benefits associated with both the Myers Cocktail and High Dose Vitamin C IV therapies, it is important that individuals consult with their IV therapy specialist before pursuing either treatment. This will ensure that they receive the most appropriate care for their individual needs and circumstances. For more information on IV therapies offered at my clinic Click Here

References

  • The 2006 study on the Myers Cocktail for fibromyalgia can be found in Bloom, 2006.
  • The 2008 study on the Myers Cocktail for chronic fatigue syndrome (CFS) can be found in Forsyth, 2008.
  • The 2015 systematic review of intravenous vitamin therapies for asthma and allergies can be found in Brown et al., 2015.
  • The 2017 study on high dose vitamin C IV infusion and cancer can be found in Kanematsu et al., 2017
  • The 2018 study on high dose vitamin C IV infusion and type 2 diabetes Mellitus (T2DM) can be found in Maeda et al., 2018
  • -The 2019 systematic review of high dose Vitamin C IV infusions for various medical conditions can be found in Wang et al., 2019(https://www.ncbi.nlm

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25/Nov/2022

If you suffer from fibromyalgia, you know that it can be a debilitating condition that causes fatigue, pain, insomnia, gastrointestinal issues and brain fog. There is no one-size-fits-all solution for fibromyalgia, but there are many natural treatments that can help lessen your symptoms. Here are 10 natural ways to treat fibromyalgia:

Rest and relaxation:

Getting enough rest is crucial for people with fibromyalgia. Taking breaks during the day and getting a good night’s sleep can help reduce fatigue and pain.
A study published in the journal Arthritis Care & Research found that people with fibromyalgia who got more than 7 hours of sleep a night reported less pain and fatigue than those who got fewer hours of sleep. Furthermore, a study published in the journal PLoS One found that people with fibromyalgia who participated in a mindfulness-based stress reduction program had reduced levels of fatigue and pain. This suggests that relaxation techniques such as yoga or meditation may help improve sleep quality and reduce fatigue and pain in people with fibromyalgia.

Exercise:

Although it may seem counterintuitive, exercise is actually one of the best things you can do for fibromyalgia. There is significant evidence to support exercise for fibromyalgia.
One study showed that a 12-week program of aerobic and resistance training improved pain, fatigue, and sleep quality in women with fibromyalgia. A review of 16 studies found that exercise was associated with significantly reduced pain intensity and improved physical function in people with fibromyalgia.
Another study showed that aquatic exercise was beneficial for reducing pain, fatigue, and improving mental health in people with fibromyalgia. Walking appears to be the most beneficial form of exercise for people with fibromyalgia, but any type of exercise that is gentle and can be sustained for a moderate amount of time is likely to be helpful. It is important to start slowly and build up gradually, listening to your body to see how much you can handle. Taking rest days when needed is also important.

Diet:

Eating a healthy diet is important for everyone, but it’s especially important for people with fibromyalgia. Some foods that are beneficial for people with fibromyalgia include omega-3 fatty acids, magnesium-rich foods, and probiotic-rich foods. One thing to avoid is trigger foods that can make symptoms worse. Common trigger foods include caffeine, alcohol, processed food, and sugar.

Supplements:

Clinical trials have shown that omega-3 supplements can be helpful for people with fibromyalgia. One study found that omega-3 supplements improved pain, fatigue, and quality of life in participants with fibromyalgia. Another study showed that omega-3 supplements reduced tenderness in the muscles of people with fibromyalgia.
Magnesium supplements have also been shown to be helpful for people with fibromyalgia. One study found that magnesium supplements improved pain and tenderness in the muscles of participants with fibromyalgia. Another study showed that magnesium supplements improved fatigue and sleep quality in participants with fibromyalgia.
Vitamin D supplements have also been shown to be helpful for people with fibromyalgia. One study found that vitamin D supplements improved pain and fatigue in participants with fibromyalgia. Another study showed that vitamin D supplements improved quality of life in participants with fibromyalgia.
Finally, turmeric supplements have been shown to be helpful for people with fibromyalgia. One study found that turmeric supplements improved pain, fatigue, and depression symptoms in participants with fibromyalgia. Be sure to talk to your doctor before starting any new supplement regimen.

Acupuncture:

Acupuncture is a traditional Chinese medicine technique that involves inserting thin needles into the skin at specific points on the body. Acupuncture has been shown to be an effective treatment for pain, fatigue, and other symptoms associated with fibromyalgia in a number of clinical trials. For example, a trial published in the journal Rheumatology International in 2012 found that acupuncture was more effective than sham acupuncture in reducing pain and fatigue in patients with fibromyalgia.
Additionally, a trial published in the journal Pain Medicine in 2013 found that acupuncture was more effective than sham acupuncture in reducing pain severity and improving function in patients with fibromyalgia. These and other clinical trials provide strong evidence that acupuncture is an effective treatment for fibromyalgia.

Massage:

Massage therapy can help relieve pain by improving circulation and relaxing tense muscles. It can also help reduce stress and promote better sleep.
Research has shown that massage therapy can be an effective treatment for pain relief in people with fibromyalgia. A study published in the journal Pain Medicine in 2016 found that massage therapy was associated with a significant reduction in pain intensity and improvement in fatigue and sleep quality in people with fibromyalgia.
Another study published in the journal BMC Complementary and Alternative Medicine in 2017 found that massage therapy was associated with a reduction in pain, anxiety, and depression symptoms in people with fibromyalgia. These findings suggest that massage therapy may be helpful for managing the symptoms of fibromyalgia.

Cannabis:

Cannabis has been shown to be an effective treatment for fibromyalgia symptoms. A 2016 study published in the Journal of Clinical Rheumatology found that cannabis was more effective than conventional therapies in treating pain, fatigue, and sleep disturbances in people with fibromyalgia. The study participants who used cannabis reported significant improvements in all measures of fibromyalgia severity, including pain intensity, fatigue, and cognitive function.
A 2017 study published in the journal Frontiers in Pharmacology found that cannabis was associated with significant reductions in pain and fatigue levels, as well as improved sleep quality. The study participants who used cannabis also reported significant improvements in quality of life.
Based on the evidence, it appears that cannabis may be an effective treatment for fibromyalgia symptoms. Cannabis is safe and easy to use, and it may provide significant relief for people who suffer from this debilitating condition.

Aromatherapy:

Aromatherapy has been shown to be beneficial for people with fibromyalgia. A study published in the journal Pain Management Nursing found that aromatherapy with lavender oil improved pain, fatigue, and sleep quality in people with fibromyalgia.
Another study published in the Journal of Alternative and Complementary Medicine found that aromatherapy with lemon balm oil improved pain, anxiety, and quality of life in people with fibromyalgia.
A study published in the International Journal of Neuroscience found that aromatherapy with bergamot oil improved pain and tenderness in people with fibromyalgia.
A study published in BMC Complementary and Alternative Medicine found that aromatherapy with chamomile oil improved anxiety and depression symptoms in people with fibromyalgia.

Laser therapy:

Laser therapy is a beneficial treatment for Fibromyalgia. It increases circulation, which helps to reduce pain and promote healing. Additionally, laser therapy is a non-invasive treatment that is relatively painless.
A study published in the “Journal of Alternative and Complementary Medicine” in 2009 found that laser therapy was able to improve pain, fatigue, and function in people with Fibromyalgia.
Additionally, a study published in “PLoS One” in 2013 found that laser therapy was able to reduce pain and improve quality of life in people with Fibromyalgia. These studies provide evidence that laser therapy may be an effective treatment for Fibromyalgia.

Intravenous vitamins and minerals:

One potential treatment for fibromyalgia is intravenous vitamin and mineral infusion. This treatment bypasses digestion and allows the vitamins and minerals to be directly absorbed into the bloodstream. The use of intravenous vitamin and mineral infusion for the treatment of fibromyalgia has been supported by a number of clinical trials.
A randomized, controlled trial published in 2011 found that the treatment was effective in reducing pain and fatigue in people with fibromyalgia. A study published in 2012 found that the infusion was associated with a significant improvement in quality of life and sleep quality.
Another study published in 2014 found that the infusion was associated with a reduction in tender points and improved self-reported pain scores. These studies provide strong evidence that intravenous vitamin and mineral infusion is an effective treatment for fibromyalgia.

Conclusion:

If you are looking for natural ways to treat Fibromyalgia, there are many options available. Some of these include: rest and relaxation techniques, exercise, diet, supplements, acupuncture, massage, cannabis, laser therapy and intravenous vitamins and minerals. It is important to speak to your naturopathic doctor about which natural therapies might be best for you. With so many options available, there is sure to be a treatment that can help improve your symptoms and quality of life.

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16/Mar/2018

Why get a license?

I want to tell you how to obtain a license for Medical Marijuana. Every month I see a handful of patients who are trying to medicate with unregulated cannabis obtained either through “a guy” or a local illegal dispensary. The problem with this approach is that you are buying an unregulated product, meaning you cannot guarantee its purity, quality, potency, and cannabinoid profile.

There are some decent products out there but largely its hit and miss and perhaps the most frequent complaint is a lack of consistency from batch to batch. Its funny how patients will be shy about discussing use of medical marijuana with me and yet will go to a complete stranger for their medication. A growing part of my practice is convincing patients to transition from their “street weed” to a proper regulated medical marijuana product.

Although, as a Naturopathic Doctor, I am not able to directly prescribe medical marijuana in Ontario, I am fortunate to have a good professional relationship with a licensing clinic and am writing an average of 3-5 patient referrals per week. Most licensing clinics will require a referral from a healthcare professional.

How to get a license

The process is quite simple: a patient will come in either having experience with cannabis or will be curious as to whether cannabis can help them. I will then preform an assessment, including a health history and short physical exam, in order to determine if they would benefit from cannabis. A referral is then made to the licensing clinic. The licensing clinic then calls the patient to setup an appointment to get a license for access to medical marijuana. Once setup with an account the patient then does all their ordering online through a regulated distributor such as Tweed, Aphria, Tilray or MedRelief.

These regulated grower/distributors have an excellent selection of strains and oils with varying cannabinoid concentrations and terpene profiles. Most importantly, the purity and potency are guaranteed and there is very high consistency from batch to batch. Therefore, if you find a strain or oil that works for you, you can pretty much guarantee it will work the same way every time you order it.

Common conditions for referral

The most common conditions I write referrals for are: Insomnia, Multiple Sclerosis, Chronic Pain, Migraine, Irritable Bowel Syndrome, PTSD, Inflammatory Bowel Disease, Cancer, Fibromyalgia and Neurological Conditions with painful spasms.

The environment in Canada with regard to cannabis is going to change as we approach legalization, but until that happens I would advise you that it is usually better to consume regulated medicines, this medication just happens to be marijuana.

 

For more great articles and information on cannabis and CBD check out the link below:CBD Oil Room


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31/Oct/2017

Clinical Endocannabinoid Deficiency

Clinical endocannabinoid deficiency, (CED), was first introduced by Dr. Ethan Russo M.D. a neurologist, psychopharmacology researcher and former advisor to GW pharmaceuticals. The theory of CED is based on the concept that many neurological conditions are associated with neurotransmitter deficiencies, for example, a deficiency in dopamine with Parkinson’s disease. Subsequently, an endocannabinoid deficiency might be present in some disorders sharing predictable clinical features.

 

All humans possess an underlining endocannabinoid system governed by two primary compounds; Anandamide (AEA) and 2-Arachidonoylglycerol (2-AG). These are compounds naturally made in our body that interact with the same receptors marijuana and associated cannabinoids act upon. It is known through various studies that when endocannabinoid tone is decrease there is a lower pain threshold, disrupted digestion, mood and sleep disturbances. A deficiency of endocannabinoids can be caused by genetics, injury or disease.

Migraine

There is evidence for CED in several treatment resistant syndromes, most notably in Migraine, Fibromyalgia and Irritable Bowel Syndrome. All three present with: heightened pain sensitivity, mood disruption, and comorbidities. One study in chronic migraine sufferers discovered a statistically significant difference in endocannabinoid concentration within the cerebral spinal fluid of chronic migraine sufferers vs. non-migraine sufferers. With migraine there is a strong association between endocannabinoids and blood vessel dilation, a key component of the propagation of migraine. Furthermore activation of the CB1 cannabinoid receptor decreases pain fiber activity in the sensory nerves of the face and head.

Endocannabinoid levels in Migraine Cerebral Spinal Fluid

It is worth noting that Cannabis was a mainstay treatment of migraine for a century between 1843 and 1943. A study from 2016 looked at the effects of medical marijuana on migraine headache frequency in adults. Headaches diminished from 10.4 to 4.6 attacks per month and overall 85.1% had decreased migraine frequency.

Fibromyalgia

Much like Migraine, Fibromyalgia is associated with hyperalgesia. In an uncontrolled trial of nine patients Tetrahydrocannabinol (THC) was administered in doses of 2.5-15mg a day for 3 months. Unfortunately 5 patients left the study early due to secondary THC side effects but those completing had marked reductions in subjective pain visual analog scales (VAS) 8.1 at start to 2.8 after 3 months. A survey of 1300 respondents called the National Pain Report from 2014 demonstrated that marijuana was the most effective treatment for Fibromyalgia compared to Duloxetine, Pregabalin and Milnacipran.

Cannabis treatment in Migraine
Cannabis most efficacious in Fibromyalgia

Irritable Bowel Syndrome

Another syndrome suspected of CED is Irritable Bowel Syndrome (IBS). The role of the endocannabinoid system in the gut is to regulate propulsion, secretion and inflammation. Cannabis was one of the first medications used for secretory diarrhea associated with cholera. A study done in 2007 demonstrated that endocannabinoids AEA and 2-AG influences the contractile force in the muscle fibers of the gastrointestinal tract. Studies also have demonstrated that there are increased levels of immunoreactive nerve fibers (TRPV1) causing pain and hypersensitivity in IBS. Cannabidiol (CBD) seems to increase AEA, which in turn reduces the activity of TRPV1. In 2007 a randomized control trial of 52 normal patients were given a single dose of 7.5mg THC. The outcome on the gastrointestinal tract was increased colonic compliance, inhibited postprandial tone, and a trend toward relaxation of fasting colonic tone.

There are a number of other conditions demonstrating evidence for CED, including motion sickness, Multiple Sclerosis, Huntington’s disease, Parkinson’s disease and Post Traumatic Stress Disorder (PTSD).

Conclusion

There is good evidence for disruption of the endocannabinoid system in Migraine, Fibromyalgia, IBS and many other neurological and psychiatric syndromes. Besides a wealth of anecdotal benefit, there exists some clinical evidence to support cannabinoids as a safe and effective treatment in these conditions. We also need to come to terms with the fact that effective medications are lacking in these conditions. An obvious shortcoming of past studies is the use of single cannabinoids for treatment such as THC. I am certain that future studies incorporating a more complete cannabinoid profile, including CBD, as a treatment approach will have far better outcomes and far fewer side effects. Lifestyle choices also play an important role in endocannabinoid function, specifically low-impact aerobic exercise. Multimodal approaches including diet, lifestyle and cannabinoid therapy will ultimately be the best approach in CED syndromes.

 

At my clinic I have repeatedly seen the benefits of cannabinoid therapy in these syndromes. After an initial assessment, if indicated, patients are referred to a medical cannabis clinic for registration under a licensed producer under the Access to Cannabis for Medical Purposes Regulations (ACMPR).


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13/Oct/2015

Title: Reduction in symptoms associated with Fibromyalgia at six weeks using Intravenous Vitamins and Minerals (Myers Cocktail).

Running Header: Myers Cocktail for Fibromyalgia

Author: Dr. Shawn Meirovici N.D.

Physio-Logic 96 Scarsedale Road, Toronto, Ontario, M3B 2R7

Disclaimer: Patient consent was obtained

Key words: Intravenous, Vitamins, Minerals, Fibromyalgia

Abstract: Fibromyalgia is a musculoskeletal disorder characterized by widespread pain commonly with one or more coexisting symptoms. Treatment often includes both non-pharmacological and pharmacological therapy. Pharmacological therapy includes the use of antidepressants and GABA derivatives with varying success rates and often with unpleasant side effects. Micronutrient infusion is a newer approach with the majority of use in the field of alternative medicine. To date one placebo controlled pilot study has examined its use in fibromyalgia patients noting statistically significant effects on pain and fatigue. The following is a case study using a similar “cocktail” as the one used in the placebo controlled trial, for 4 treatments using the modified visual analogue scale of the fibromyalgia impact questionnaire (mVASFIQ) as an endpoint measure. Significant reduction in all parameters of the mVASFIQ was noted at 6 weeks, suggesting that micronutrient infusion should be further investigated as a treatment approach for fibromyalgia.

 

Background: I have a special interest in the treatment of chronic pain. Operating out of a rehabilitation clinic in Toronto, Canada has allowed me the opportunity to work with neurological conditions and traumatic injuries of which chronic pain is often a prevalent symptom. Fibromyalgia is characterized by chronic widespread pain and often involves disruption of many body systems including the gastrointestinal tract. While pharmaceutical intervention is focused on regulating the body’s response to pain, many alternative therapies are focused on restoring function to debilitated body systems. One such treatment is the Myers Cocktail: a intravenous micronutrient therapy that delivers vitamins and minerals directly into the blood stream thereby  bypassing the gastrointestinal tract. There is both a review and placebo controlled pilot study demonstrating intravenous micronutrient therapy as an effective treatment for symptom reduction in fibromyalgia. [1] [2]

 

Introduction: Fibromyalgia is characterized by chronic widespread pain, increased tenderness at specific sites known as “tender points,” un-refreshing sleep, fatigue and cognitive dysfunction not attributable to other disease states. While the etiology of fibromyalgia is not entirely clear, associations with trauma, adverse life events, impaired mood, anxiety, irritable bowel syndrome, cold intolerance, paresthesias and other medical conditions have been described. The pharmacologic treatment of fibromyalgia ranges from antidepressants to analgesics. Here we are commenting on a novel treatment involving the infusion of vitamins and minerals also known as a Myers Cocktail.

 

Case Presentation: J.M. is a 38-year old female who had been diagnosed with fibromyalgia in 2008. Her  symptoms started approximately 10 years ago after enduring a series of traumatic life events. Symptoms included: chronic widespread pain, non-restorative sleep, muscle weakness, morning stiffness, subjective swelling, multiple chemical sensitivities, frequent severe headaches, vestibular dysfunction, TMJ, paresthesia, chronic fatigue, dysmenorrhea, anxiety and irritable bowel syndrome. J.M. had tried a number of GABA derivatives, antidepressants and analgesics with varying degrees of relief but with significant adverse reactions including aphasia, depression and dyspepsia. At initial presentation, J.M. was taking Wellbutrin 300mg XL daily and Tylenol with Codeine as needed. She felt that she was starting to develop a tolerance to Wellbutrin. She was not taking any dietary supplements and was not on any type of specialized diet or exercise program.

J.M. was prescribed an intravenous infusion Myers Cocktail (B-complex 1ml, Dexpanthenol 250mg, Pyridoxine 100mg, Hydroxocobalamin 1mg, Ascorbic Acid 2000mg, Calcium Chlroide 100mg, Magnesium Chloride 1000mg and Sterile Water 46ml) via 60cc syringe with a 24 Gauge butterfly needle at the right median cubital vein, delivered over 15 minutes once per week for 4 infusion sessions. This patient completed a modified visual analogue scale of the fibromyalgia impact questionnaire (mVASFIQ) at initial consult (Image 1) and again after her final infusion (Image 2). She was also prescribed magnesium malate 1.5 grams per day, 1000iu vitamin D per day and 1mg melatonin at night 30 minutes before sleep. However, J.M. was admittedly not taking these supplements consistently during the 4 weeks of intravenous treatment.

The mVASFIQ score at treatment initiation was: (Fatigue 9.5, Insomnia 9.5, Depression 4.5, Anxiety 6.5, Rigidity 8.5, Pain 8.5, Difficulty with work 8.5) at four weeks the mVASFIQ score was: (Fatigue 3, Insomnia 5, Depression 1, Anxiety 3, Rigidity 3, Pain 3, Difficulty with work 3). Besides mild nausea and flushing during the first treatment no adverse effects were reported.

 

Discussion: Micronutrient infusion delivers vitamins and minerals involved in stress response, muscle contraction and nerve signaling, while able to bypass the need for gastrointestinal absorption. This is an effective delivery method for chronic conditions, such as fibromyalgia, where there is often gastrointestinal disruption as well as the potential for micronutrient deficiencies. The results of this case study demonstrate that micronutrient infusion Myers Cocktail may be an effective treatment for fibromyalgia related symptoms as indicated by a  decreased in symptoms score on mVASFIQ at 6 weeks post treatment. This joins the small collection of evidence for the validity of this treatment for fibromyalgia. More study into this treatment for fibromyalgia is warranted.

 

Confounding Factors: As was outlined in the treatment plan, J.M. received a few dietary supplements on initial consult; however, J.M. admitted to not taking these consistently throughout the 4 intravenous treatments. The patient received all 4 infusions by myself and was not blinded to the treatment. There was also no placebo control. Additionally, the patient may have been influenced by the doctor patient relationship or through placebo effect. However the significant improvement observed within a relatively short time helps to validate the results of this study.

[1] Intravenous Micronutrient Therapy (Myers’ Cocktail) for Fibromyalgia: A Placebo-Controlled Pilot Study, Ather et al., The Journal of Alternative and Complementary Medicine, Volume 15, Number 3, 2009, pp. 247-257

[2] Myers’ Cocktail, Dr. Alan Gaby M.D., Alternative Medicine Review, Volume 7, Number 5, 2002.

 Image 1

Table 1

mVASFIQ for J.M. on July 18th 2015 (patient incorrectly marked X in box rather than a check through the appropriate line, therefore, results have +/- 0.5 confidence interval.

Image 2

Table 2

mVASFIQ for J.M August 28th 2015.


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