Probiotics help boost the immune system – Studies have shown that probiotics affect immune cells throughout the body. When certain strains of probiotics are introduced into our intestine they help to repair intestinal cells and they boost production of antimicrobial substances. In one study, 326 children aged 3-5 years were randomly assigned to receive, in double-blind fashion, probiotic supplementation. Treatments were given twice per day in divided doses for 6 months, including the winter season. Compared with placebo, the probiotic group had the following results; fever reduction 53-73%, cough reduction 41-62%, decreased runny nose 28-59%, decreased need for antibiotics 68-82%, reduced absence from school 28-32%.
Elderberry extracts inhibit bacteria and viruses – Not only does elderberry syrup taste great, studies have shown that it inhibits the bacteria and viruses associated with common colds and the flu. One study demonstrated that an elderberry liquid extract possesses antimicrobial activity against both streptococci bacteria and influenza viruses. Another study looked at 312 air travellers flying from Australia to an overseas destination. Those travellers who took an elderberry extract before, during and after travel had fewer colds, less sick days and less symptoms.
Vitamin C supports immune cells – Vitamin C is very important for optimal immune system functioning. Vitamin C helps immune cells get to where they need to be, kill pathogens effectively, protect the body from damage and clean up after battling infections. Studies have shown that adequate vitamin C in the blood helps prevent infections, is necessary to fight infections and helps with recovery. The recommended daily intake of vitamin C is 100-200mg/day; however during active infection, the metabolic demand increases and therefore the requirement for vitamin C is likely to be higher. Even in this day and age, vitamin C is the fourth leading nutrient deficiency in North America. Poor diet and increases in free radical exposure due to an unhealthy lifestyle may be contributing factors. Excellent sources of vitamin C are Broccoli, Citrus Fruits and Berries.
Zinc is essential for immune system communication – The importance of zinc for proper immune function has been well established. Zinc deficiency undoubtedly causes immune system malfunction. The cells of our body are in constant communication. During infection there is a need for effective communication between immune cells in order to get rid of the “bad guys”. Communication happens in the form of chemical messengers and enzymes. Zinc is an essential component of these chemicals and enzymes. As with vitamin C, during active infection our requirement for zinc is likely to increase. Studies have shown that Zinc supplementation during infection can shorten the duration of the illness. Excellent dietary sources of zinc include: Meat, Shellfish, Legumes, Nuts and Seeds. Supplementation may be important with a vegan or vegetarian diet.
Vitamin D is the supervisor of the immune system –Vitamin D has many functions in the body, and receptors for vitamin D can be found on many different tissues. One important function for vitamin D is in the modulation of our immune system. Studies have suggested that vitamin D is able to both calm down and rev-up the immune system according to what our body needs it to do. This is why Vitamin D is thought to be as important in autoimmune disorders as it is in infections.
Vitamin D deficiency can cause the immune system to behave erratically. Unfortunately in Canada we have one of the highest incidences of vitamin D deficiency in the world. Our primary source of vitamin D is from sunlight and therefore supplementation becomes important especially during the winter months. Studies have shown that there is a higher incidence of upper respiratory tract infections in athletes who are deficient in the vitamin and who train in the wintertime. Supplementation had preventative and symptom reducing effects. Aside from sunlight, some dietary sources of vitamin D are: fortified foods, fatty fish, beef liver, egg yolks and cheese.
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Leyer, GJ et al. Probiotic effects on cold and influenza-like symptom incidence and duration in children. Pediatrics 2009; 124-179. Walker, WA. Mechanisms of action of probiotics. Clin Infect Dis. 2008; 46 (Suppl2): S87-91.
Curr Opin Gastroenterol. 2011 October ; 27(6): 496–501. doi:10.1097/MOG.0b013e32834baa4d. Probiotics and immune health Fang Yana and D.B. Polkb,c,d
Elderberry Supplementation Reduces Cold Duration
and Symptoms in Air-Travellers: A Randomized,
Double-Blind Placebo-Controlled Clinical Trial Evelin Tiralongo 1,2, *, Shirley S. Wee 2,3 and Rodney A. Lea 4 Received: 8 February 2016; Accepted: 18 March 2016; Published: 24 March 2016
Krawitz et al. BMC Complementary and Alternative Medicine 2011, 11:16
http://www.biomedcentral.com/1472-6882/11/16
Inhibitory activity of a standardized elderberry
liquid extract against clinically-relevant human
respiratory bacterial pathogens and influenza A
and B viruses Christian Krawitz1†, Mobarak Abu Mraheil1†, Michael Stein2, Can Imirzalioglu1, Eugen Domann1, Stephan Pleschka2*,
Torsten Hain1*
Vitamin C and Immune Function Anitra C. Carr 1, * and Silvia Maggini 2
1 Department of Pathology, University of Otago, Christchurch, P.O. Box 4345, Christchurch 8140, New Zealand
2 Bayer Consumer Care Ltd., Peter-Merian-Strasse 84, 4002 Basel, Switzerland; silvia.maggini@bayer.com* Correspondence: anitra.carr@otago.ac.nz; Tel.: +643-364-0649 Received: 21 September 2017; Accepted: 31 October 2017; Published: 3 November 2017
Biofactors. 2014 Jan-Feb;40(1):27-40. doi: 10.1002/biof.1114. Epub 2013 Jun 27.Zinc signals and immune function. Haase H1, Rink L.
Cochrane Database Syst Rev. 2013 Jun 18;(6):CD001364. doi: 10.1002/14651858.CD001364.pub4. Zinc for the common cold.
Vitamin D3 Supplementation Reduces the Symptoms
of Upper Respiratory Tract Infection during Winter
Training in Vitamin D-Insufficient Taekwondo
Athletes: A Randomized Controlled Trial Hyun Chul Jung 1 , Myong-Won Seo 2 , Sukho Lee 3 , Sung Woo Kim 2 and Jong Kook Song 2, * 1 Department of Kinesiology, College of Health Sciences, University of Louisiana at Monroe, 700 University
Avenue, Monroe, LA 71209, USA; jung@ulm.edu
2 Department of Taekwondo, College of Physical Education, Kyung Hee University, 1732 Deokyoungdaero, Giheung-gu, Yongin-si, Gyeonggi-do 17014, Korea; smilly1004@khu.ac.kr (M.-W.S.); kswrha@khu.ac.kr (S.W.K.)
3 Department of Counseling, Health, and Kinesiology, College of Education and Human Development,Texas A&M University-San Antonio, One University Way, San Antonio, TX 78224, USA; slee@tamusa.edu* Correspondence: jksong@khu.ac.kr; Tel.: +82-31-201-2708 Received: 2 August 2018; Accepted: 10 September 2018; Published: 14 September 2018
Mechanisms Underlying the Regulation of Innate and
Adaptive Immunity by Vitamin D Ran Wei and Sylvia Christakos *
Received: 25 June 2015 ; Accepted: 15 September 2015 ; Published: 24 September 2015 Department of Microbiology, Biochemistry and Molecular Genetics, New Jersey Medical School, Rutgers, the State University of New Jersey, 185 South Orange Ave, Newark, NJ 07103, USA; weira@njms.rutgers.edu
* Correspondence: christak@njms.rutgers.edu; Tel.: +973-972-4033; Fax: +973-972-5594
Do you give your kids probiotics?
Every year it seems like the back to school commercials start to pop up earlier and
earlier in the summer months. Although these commercials are aimed at bringing
parents into office supply and clothing stores in prep for their kids returning to
school, as parents we can also use this time to implement nutritional strategies to
help our kids excel during the school year.
Besides the obvious beneficial lifestyle approaches like eating a balanced nutrient
rich diet and daily exercise, there are a few specific recommendations that may help
your kids have the edge when it comes to starting school.
[banner ]Probiotics[/banner]
Probiotics are live bacteria cultures that seem to have varying health benefits when
introduced into our gastrointestinal tract. Probiotics are naturally found in many
fermented foods such as yogurt, kefir, miso, tempeh, sauerkraut and kombucha. It is
believed that as a species, fermented foods played a larger role in our diet as we
evolved and our bodies have grown to rely on these bacterial cultures for optimal
health and wellbeing. Our modern “western” diet has been relatively low in these
fermented foods and there have been hypothesis relating many chronic diseases of
the gastrointestinal tract and immune system back to imbalanced gut bacteria.
Subsequently we have witnessed a surge in probiotics being offered in supplemental
form as a way to help restore this balance. It is important that I stress the fact that
probiotics alone are not the complete picture with regard to a healthy
gastrointestinal and immune system but research has suggested that they do play a
part.
Probiotics help boost the immune system – with kids heading back indoors and
spending large amounts of time in classrooms with each other (including daycare),
there is a dramatic increase in germ exposure and potential for kids to fall prey to
illness. In one study, 326 children aged 3-5 years were randomly assigned to
receive, in double-blind fashion, probiotic supplementation. Treatments were given
twice per day in divided doses for 6 months, including the winter season. Compared
with placebo, the probiotic group had the following results; fever reduction 53-73%,
cough reduction 41-62%, decreased runny nose 28-59%, decreased need for
antibiotics 68-82%, reduced absence from school 28-32%.
Probiotics help with allergies – Heading back indoors can trigger many kids who
are especially allergic to dusts and molds. With regard to asthmatic children with
allergic rhinitis, studies have shown the use of probiotics resulted in a significant
reduction in the inflammatory immune chemistry produced by peripheral blood
mononuclear cells. Further studies have shown specific down-regulation of T cells
(immune cells), which beneficially alter the balance of pollen specific antibodies in
seasonal allergic rhinitis. In short – probiotics lower the allergic load and decrease
inflammation.
Probiotics help with mood – Recent research is showing new gut-brain
connections as happy gut ecology seems to make for happier brains. In one
particular study, anxious mice dosed with probiotics showed lower levels of anxiety,
decreased stress hormones, and even increased brain receptors for
neurotransmitters vital in curbing worry, anxiety and fear. With better mood comes
greater ease and ability to learn in school settings and beyond.
Stay tuned for part 2 which will focus on cold/flu prevention and treatment.
Book a consultation with our Naturopathic Doctor Shawn Meirovici for
more information on child-friendly probiotic strains and dosages.
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Leyer, GJ et al. Probiotic effects on cold and influenza-like symptom incidence
and duration in children. Pediatrics 2009; 124-179.
Walker, WA. Mechanisms of action of probiotics. Clin Infect Dis. 2008; 46 (Suppl
2): S87-91.
Yang, G et al. Treatment of Allergic Rhinitis with Probiotics: An alternative
approach. N Am J Med Sci. Aug 2013; 5 (8): 465-68.
Javier, AB, Forsytthe, P & Cryan, J. Ingestion of Lactobacillus strain regulates
emotional behavior and central GABA receptor expression in mice via the vagus
nerve. Proc Natl Acad Sci USA. Sep 20, 2011; 108(38): 16050-55.
It’s the summer of 2018 and it’s a hot one. Having fun in the sun is what we dream about all winter long and while we do benefit from some sun exposure (boosting levels of vitamin D and serotonin) we must also balance sun exposure with sun protection. In this article I will outline some general guidelines with reference to safe sun exposure, getting enough vitamin D and how consuming certain foods may help further protect us during recommended exposure times.
Exposure
According to recent research we now know that vitamin D is not only important for strong healthy bones but also plays a role in preventing some chronic diseases like Multiple Sclerosis and Cancer. So we need to know some general guidelines for getting the right amount of sun exposure while helping protect ourselves from damaging UV radiation.
In 2001 the Australian Radiation Protection and Nuclear Safety Agency set out to determine daily UV radiation levels in major cities across Australia. How much sun was needed to produce adequate levels of vitamin D and how much exposure could produce damage to the skin was investigated. The general guidelines to come out of the report were as follows: In the peak of the summer, July and August in North America, “2 to 14 minutes of sun three to four times per week at midday will give fair-skinned people with 15 per cent of the body exposed the recommended amount of Vitamin D. However, redness (skin damage) can occur in only eight minutes in these conditions.
So in peak summer times from 10 am to 3pm, you should use protection against the sun; shade, hats, clothing, sunglasses and sunscreen.
But earlier in the day and later in the afternoon, for a similar period of sun exposure and vitamin D manufacture, you get much less skin damage.”(http://www.abc.net.au/health/thepulse/stories/2006/04/05/1609208.htm)
For the months just before and after the peak summer months (June and September) the study revealed that the time of sun exposure needed for adequate vitamin D levels increases to 10 to 15 minutes 3-4 times per week. In the fall, winter and early spring months we need short periods of exposure during peak times of the day 10am-3pm in order to make enough vitamin D.
Sun-Blocking Foods
The question then becomes; in those times of recommended sun exposure how do we further protect ourselves from the damage of UV radiation? Part of the answer may be in the food we eat and beverages we drink. UV radiation helps us to make important compounds such as vitamin D but it can also cause damage to our cells. Cellular damage occurs via the production of inflammation and damaging compounds called free radicals. Some important compounds in our diet that combat inflammation and free radicals are: Omega-3 fatty acids and Antioxidants.
Antioxidants are compounds found in fruits and vegetables that serve to protect the plant against the harmful effects of its environment, including UV radiation. Many of these antioxidants incur the vibrant colors we associate with fruits and vegetables onto them.
Lycopene is a powerful antioxidant found in red colored fruits and vegetables such as: Tomatoes, Watermelon, Guava, Grapefruit, Papaya and Red Peppers including Chili Pepper. Lycopene is most easily absorbed when it has been cooked, making tomato paste and cooked tomatoes an excellent source of bio-available lycopene. Not only does this antioxidant protect the fruit/vegetable from UV damage, when we consume lycopene, it protects our body as well.
Anthocyanidins are a group of antioxidants that incur free radical protection and have a dark red or purplish color. Rich sources of anthocyanidins include: Blueberries, Acai, Pomegranate, Blackberries and Cherries.
The flavonoid antioxidants in green tea include the very powerful polyphenol EGCG. EGCG has not only been shown to inhibit tumor cells in some cancers but has also been shown to protect cells from the aging effects of UV radiation. Particularly matcha green tea (pulverized powdered tea leaves) can be 137 percent higher in EGCG than regular water infused tea leaf. Dark chocolate is also very high in phenols and can incur a 25 percent increase in sun tolerance at 2 ounces of over 70% cacao per day.
Another compound important for protecting our body against the potentially harmful effects of sun exposure are omega-3 fatty acids. These fatty acids help to drive an anti-inflammatory pathway in the body. Radiation and chronic disease induces inflammation which can lead to cellular damage and premature aging. Fish is an excellent source of omega-3 fatty acids, particularly Salmon, Herring, Mackerel, Trout and Sardines. It is recommended to eat at least 2 servings of high omega-3 fish per week or to take a fish oil supplement daily.
Another good source of omega-3 fatty acids are flaxseeds. Flaxseeds also contain compounds called lignans which may protect against the development of some cancers. It is recommended to have a half teaspoon of ground flaxseeds per day or a flaxseed oil supplement.
Although these are all specific examples of foods rich in sun protecting compounds, a good general rule of thumb is too eat plenty of vibrantly colored fruits and vegetables which will undoubtedly be rich in antioxidants. It is also just as important to limit foods which can cause free radical damage and inflammation, these include: sugar and red meats.
Equip your body with sun protecting foods and follow the guidelines as to when to allow for uninhibited sun exposure. By doing so you will make the D and be problem free.
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One goal of Naturopathic pediatrics is to use natural therapies to prevent and treat mild to moderate conditions, resorting to pharmaceutical and surgical interventions as secondary options or in emergency situations. The core belief in Naturopathic pediatrics is to encourage the body to heal itself. This is achieved through supporting the immune system, addressing nutritional deficiencies, promoting a healthy diet and lifestyle; including exercise, sleep and mental habits.
Disease as a Process
Fever is an excellent example of how a naturopathic approach may differ from a conventional approach. A fever is our natural defence mechanism against a pathogen. By raising the temperature of the body a few degrees many pathogens (viruses, bacteria) stop functioning optimally and the body activates inflammatory immune cells and enzymes to destroy the invading organism. While conventional medicine often sees disease symptoms, like a fever, as something to be suppressed, naturopathic doctors often see them as something to be promoted.
It has become commonplace to try to intervene in the disease process too swiftly, taking medications to decrease fever and inflammation prematurely. The Naturopathic Doctors role is to recognize the stages of the disease process, closely monitoring a fever, knowing when a fever should be left alone and when intervention is necessary. All the while helping the child feel better without interfering in the healing process.
There are generally 5 stages of the disease process: Incubation, Aggravation, Destruction, Abatement and Reconstruction.
Incubation is where the invading organism is accumulating in certain areas of the body. This process can take hours to days to weeks to months. The immune system reacts and either removes the organism or the organism replicates too quickly and the body moves to the next stage. It is common to not have any obvious signs of infection during this stage.
Aggravation includes the usual signs of inflammation, replication of immune cells, fever, redness, pain, malaise, loss of appetite and fatigue. These are signs that the immune system is hard at work and should be encouraged. This is where suppression commonly occurs with fever reducing medications, and anti-inflammatories, which can revert healing back to the incubation phase.
Destruction is the peak of inflammation and results in the destruction of one organism or another.
Abatement occurs when the fight is over and it’s time to clean up the debris. The immune cells, dead organisms and inflammatory fluids must be removed by the body. The fever “breaks” and sweating begins. Coughing up phlegm, runny nose, diarrhea and other discharges remove the debris from the body. In conventional medicine, cleanup is often viewed as an additional set of annoying symptoms that need to be suppressed by drugs, often impeding on the “cleanup” process.
Fever reductions after administering fever reducing medications should not be confused with abatement. The fever will often spike again. The immune system is trying to do its job but is being suppressed.
Reconstruction happens next. The body is reconstructing damaged tissue, the body is attempting to reset back to its original state.
Most pediatric infections will run their course, and the child will heal themselves. The Naturopathic Doctor watches the disease process closely, waiting to see if the body will heal or get worse requiring intervention. Besides making this decision, it is also the Naturopathic Doctors role to encourage processes like fevers, rather than suppress healing and teach parents to save fever reducing medications until necessary.
Intervention
The Naturopathic Doctor monitors the inflammatory process, only intervening to prevent a severe state of aggravation. Mild interventions such as cooling baths, friction rubs, warming socks can often lower a high fever and help the child feel better. These therapies have their limits and are not always sufficient. It is also the Naturopathic Doctors role to recognize an emergency situation that requires pharmaceutical intervention and to educate the family with regard to monitoring the disease and recognizing an emergency situation.
Safety
The first principle of Naturopathic Medicine is “primum non nocere” first, do no harm. Safety is a combination of good diagnostics, good choice of treatments, prevention, and physician intervention when necessary. The properly trained, properly regulated Naturopathic Doctor should be able to guide the family through a confusing landscape of both conventional and non-conventional medicine by knowing which “alternative” approaches are safe and effective and when referral to another integrative professional or physician will be in the best interest of the infant, child or adult.
Dr. Shawn is now at KidCrew Fridays from 10am-6pm