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11/Sep/2022

Intro

According to the National Sleep Foundation, “insomnia is defined as repeated difficulty with sleep initiation, maintenance, consolidation, or quality that occurs despite adequate opportunity and circumstances for rest,” and it affects approximately 30-35% of adults. If you’re one of the millions of people struggling to get a good night’s sleep, know that you’re not alone—and there are naturopathic treatments that can help!

Sleep Hygiene

One of the best things you can do to improve your sleep is to practice good sleep hygiene. This includes habits like avoiding caffeine in the afternoon and evening, avoiding alcohol before bed, Establishing a regular sleep schedule, and avoiding screens in the bedroom. Creating a relaxing bedtime routine can also be helpful; consider taking a bath or reading a book before climbing into bed.

Nutraceuticals

There are also a number of nutraceuticals—or nutrients that have medicinal properties—that can help improve sleep. Melatonin is a hormone that helps regulate the body’s natural sleep-wake cycle, and supplements can be effective in treating insomnia. 5-HTP is another nutrient that can be helpful in treating sleeplessness; it works by increasing levels of serotonin, a neurotransmitter that plays an important role in regulating sleep. Other nutrients that have been shown to be effective in treating insomnia include gamma-aminobutyric acid (GABA), valerian root, and passionflower.

Traditional Chinese Medicine Moxabustion
Moxabustion

Traditional Chinese Medicine

Traditional Chinese Medicine (TCM) offers another treatment option for those struggling with insomnia. Acupuncture is one of the most well-known TCM treatments; research has shown that it can be effective in treating insomnia by promoting relaxation and improving sleep quality. Herbal medicine is another TCM modality that can be helpful in treating sleeplessness. Traditional Chinese herbs that have been used to treat insomnia include jujube seed, ziziphus seed, longan fruit, tianma root, ginseng root, and magnolia bark.

Cannabis

Cannabis is another treatment option that is gaining popularity for its ability to effectively treat insomnia. THC, the primary psychoactive compound in cannabis, has been shown to increase slow-wave sleep—the deepest stage of sleep—while CBD has been shown to reduce REM sleep density, which may lead to more restful sleep. For those who are interested in trying cannabis for their insomnia but are worried about the potential for addiction or abuse, CBD-only products may be a good option as they do not have any psychoactive effects.

Conclusion

If you’re one of the millions of people affected by insomnia, know that you’re not alone—and there are treatments out there that can help! Sleep hygiene practices like avoiding caffeine and screens before bed can make a big difference, and nutraceuticals like melatonin and 5-HTP can also be effective in treating sleeplessness. Traditional Chinese Medicine modalities like acupuncture and herbal medicine can also offer relief from insomnia; cannabis is another treatment option gaining popularity for its ability to improve sleep quality. Talk to your naturopathic doctor about which treatment option may be right for you!

Book an appointment today!


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19/Aug/2022

Are you feeling tired, moody, and bloated? You might be experiencing the symptoms of hormone imbalance. This is a common problem for women, especially mothers. But don’t worry, there are natural treatments that can help restore your hormones to balance. In this blog post, we will discuss what hormone imbalance is, its symptoms, and how to treat it naturally. Keep reading to learn more!

Estrogen Dominance

Estrogen dominance is a condition that can occur when there is an imbalance of estrogen and progesterone in the body. When estrogen levels are too high relative to progesterone levels, it can lead to a number of symptoms, including mood swings, bloating, fatigue, and irregular menstruation.

Estrogen dominance can be caused by a variety of factors, including stress, diet, and certain medications. If you are experiencing any of these symptoms, we can help to properly diagnose and treat the condition. Estrogen dominance is a common hormonal imbalance that affects many women, but with proper treatment, it can be effectively managed.

BHRT

Bioidentical hormone replacement therapy is a treatment for estrogen dominance that involves using hormones that are identical to the ones produced by the body. This type of therapy can be used to treat a variety of symptoms associated with estrogen dominance, such as hot flashes, night sweats, mood swings, and weight gain. Bioidentical hormone replacement therapy can also help to protect against osteoporosis and heart disease.

While traditional hormone replacement therapy uses synthetic hormones that are not identical to those produced by the body, bioidentical hormone replacement therapy uses hormones that are exact replicas of the ones naturally produced by the body. This makes bioidentical hormone replacement therapy a more natural and effective treatment for estrogen dominance.

PCOS

Polycystic ovary syndrome (PCOS) is a hormonal disorder that affects women of reproductive age. The four main features of PCOS are insulin resistance, high levels of testosterone, low levels of follicle-stimulating hormone (FSH), and high levels of luteinizing hormone (LH). Insulin resistance is the most common cause of PCOS, and it occurs when the body doesn’t use insulin effectively. This leads to higher than normal levels of Insulin in the body. High Insulin levels increase testosterone production, which can interfere with the development of follicles on the ovaries. As a result, ovulation may be irregular or may not occur at all.

FSH is responsible for stimulating the growth of follicles on the ovaries, and LH is responsible for triggering ovulation. When FSH and LH are out of balance, it can lead to PCOS.

Cortisol is a stress hormone that can also contribute to PCOS. It does this by increasing Insulin Levels and affecting how the body uses glucose. As a result, women with PCOS often have higher than normal levels of Cortisol in their bodies.

PCOS can cause a variety of symptoms, including weight gain, irregular menstruation, fertility problems, low sex drive, and mood swings. PCOS can also cause acne and excess hair growth. While there is no cure for PCOS, there are treatments that can help manage the symptoms.

PCOS is thought to be caused by a combination of genetic and environmental factors. A woman’s risk of developing PCOS increases if she has a family history of the condition. PCOS is also more common in women who are overweight or obese. If you think you may have PCOS, talk to your doctor about your symptoms.

Diet and exercise are two of the most important factors in managing PCOS. Both help to regulate hormone levels and improve insulin sensitivity. One of the best ways to get started is to eat a nutritious diet and to get at least 30 minutes of exercise every day.

Additionally, supplements like l-carnitine, inositol, and vitamin D can be helpful in managing PCOS symptoms. L-carnitine helps to boost energy levels and improve fertility, while inositol helps to regulate hormones and reduce inflammation.

Vitamin D is essential for fertility and has also been shown to improve insulin sensitivity. All of these nutrients are available in food sources or supplements. By making dietary and lifestyle changes, you can help to manage your PCOS symptoms naturally.

Chronic Stress

Estrogen, testosterone, and other hormones play a vital role in the human body. They are involved in regulating mood, energy levels, metabolism, and sexual function. However, these hormones can be easily disrupted by stress.

When the body is under stress, it releases a hormone called cortisol. cortisol helps the body to deal with short-term stressors by increasing heart rate and blood pressure. However, if cortisol levels remain high for long periods of time, it can interfere with the production of other hormones, including estrogen and testosterone. This can lead to a number of problems, such as fatigue, weight gain, and difficulty concentrating.

Additionally, stress can also disrupt the delicate balance of progesterone and estrogen, which can lead to irregular periods and hot flashes in women. Therefore, it is important to manage stress in order to maintain hormone balance.

Diet, exercise, meditation, sleep and adaptogens are all effective ways to manage stress naturally. Diet can help by reducing inflammation and providing the nutrients needed for the body to function optimally. Exercise releases endorphins, which have mood-boosting effects, and also helps to reduce levels of the stress hormone cortisol.

Meditation helps to focus and calm the mind, and research has shown that it can be as effective as medication for treating anxiety and depression. Sleep is essential for rest and recovery, and 7-8 hours per night is recommended for most adults.

Adaptogens are a unique class of herbs that help the body to adapt to stressors by modulating the stress response. When used regularly, they can help to prevent burnout and promote resilience. Managing stress naturally requires a holistic approach, but incorporating these simple strategies into your daily routine can make a big impact.

If you’re experiencing any of the symptoms we’ve talked about, it might be time to see a naturopathic doctor. NDs are experts in hormonal balance and have many natural and effective treatments at their disposal. Don’t suffer in silence – book a consultation today and start feeling like yourself again.


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15/Aug/2022

Do you feel like you’re always getting sick? Are you constantly battling colds and the flu? If so, you may need to boost your immunity. Luckily, there are a number of natural treatments that can help. In this blog post, we will discuss some of the best ways to improve your immune system naturally.

Vitamin D for immunity

Vitamin D is essential for a strong immune system. It helps the body to produce antibodies, which fight infection. Vitamin D can be found in fatty fish, eggs, and fortified milk. You can also get Vitamin D from exposure to sunlight.

Trouble keeping up with vitamin D supplements and worried about sun exposure? Not to worry, at my clinic we offer the option of a vitamin D injection. Under professional supervision, this is a safe and effective way to boost vitamin D levels quickly.

Vitamin C for immunity

Another important nutrient for immunity is Vitamin C. Vitamin C helps the body to create white blood cells, which fight infection. Vitamin C can be found in citrus fruits, tomatoes, bell peppers, and broccoli.

Intravenous vitamin C is a great way to get a high dose of Vitamin C. By bypassing digestion, IV vitamin C can boost levels quickly. Intravenous vitamin C can also increase blood concentrations at levels that directly kill pathogens and inhibit cancer growth.

Zinc for immunity

Zinc is another important mineral for immunity. It helps the body to create new cells and enzymes that fight infection. Zinc can be found in oysters, beef, pork, chicken, and beans.

Zinc can also be added to intravenous infusions for an added immune system boost.

Elderberry Syrup

If you’re looking for a kid friendly and great tasting way to boost your immunity, elderberry syrup is a great option. Elderberries are rich in Vitamin C, Vitamin A, and antioxidants. They have been shown to reduce inflammation and fight infection. You can find elderberry syrup at most health food stores.

Ginger for immunity

Ginger is another great option for boosting your immunity. Ginger is a natural anti-inflammatory and can help to reduce congestion. It can also help to soothe a sore throat. You can find ginger in the form of capsules, tea, or syrup.

Garlic for immunity

Garlic is another excellent food for boosting your immunity. Garlic is rich in Vitamin C, sulfur, and antioxidants. It has been shown to fight infection and reduce inflammation. You can add garlic to your food or take it in supplement form.

Selenium for immunity

Selenium is a trace mineral that is important for immunity. Selenium helps the body to produce antibodies, which fight infection. It can be found in Brazil nuts, tuna, shrimp, and eggs.

Selenium can also be added to an intravenous infusion for an added immune boost.

Vitamin A for immunity

Vitamin A is an important nutrient for immunity. Vitamin A helps the body to produce white blood cells, which fight infection. Vitamin A can be found in sweet potatoes, carrots, dark leafy greens, and squash.

Probiotics for immunity

Probiotics are live bacteria that are good for your gut health. Probiotics help to keep the balance of good and bad bacteria in your gut. This can help to improve digestion and boost immunity. You can find probiotics in yogurt, kimchi, sauerkraut, and kombucha.Probiotic supplements are also available.

There you have it! These are just a few of the best ways to boost your immunity naturally. By including these foods and supplements in your diet, you can help to keep yourself healthy and avoid getting sick. In individuals requiring an extra boost, injection and intravenous treatments are available and effective. Do you have any other favourite natural immunity boosters? Share them with us in the comments


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26/Jul/2022

What is PCOS?

Finding an effective treatment for Polycycstic ovarian syndrome (PCOS) is important to me for two distinct reasons. 5-10% of woman are impacted by PCOS in their lifetime making PCOS a common and treatable condition in my Naturopathic practice. The second reason is that it is a condition that my wife has struggled with for many years therefore making it a syndrome that hits close to home.

PCOS is a bit of a misnomer as it is a continuum of symptoms and doesn’t necessarily have to include ovarian cysts. It is however characterized by several common objective findings including irregular periods, infertility, shifts in hormone balance (DHEA, Testosterone, LH, FSH), hirsutism (hair growth on the lip, chin and abdomen), Hair loss (Male pattern head hair loss), acne (typically on the lower jaw), high levels of insulin due to insulin resistance, and unexplained weight gain (especially around the abdomen).

Although we still do not know all the mechanisms involved as to why some women develop PCOS, there does seem to be a genetic component. Environmental toxins such as BPA seem to play a role, and gastrointestinal dysbiosis (unfriendly bacteria in the gut) plays a role as well.

Conventional Treatment for PCOS

Some of the more common conventional treatments of PCOS include birth control pill (to regulate irregular periods and hormone levels), metformin (a insulin sensitizing drug that helps to control blood sugar levels commonly used in diabetes), and spironolactone (a diuretic that also has the ability to block a type of testosterone formation called DHT). While these treatments can be helpful in the short-term they do not always address the root cause of PCOS and therefore ultimately fail in the long term. Some of these causes include hormone disrupters in the environment and diet, and gastrointestinal dysbiosis (leading to the production of inflammatory compounds that compromise insulin function).

Holistic Treatment for PCOS

Luckily there are relatively easy and low cost solutions to many of the fundamental causes of PCOS. As a Naturopathic Doctor I have the privilege and ability to take a detailed medical history. Doing so can point me in the direction(s) as to where these foundational imbalances are occurring. For instance if the patient has a history of gastrointestinal concerns, (constipation, diarrhea, gastritis, colitis) that informs me to focus investigation on the gastrointestinal tract. If a patients main concern is infertility and irregular periods I will shift focus into hormone balance. It may also be the case that a patient has several concern at the same time, which is not uncommon in PCOS. Once I know where to focus we can run specialized tests such as comprehensive stool analysis, female hormone panels, nutrient level panels, food sensitivity testing and environmental toxins. This aids in narrowing down where to implement the bulk of the treatment protocol. There are some general recommendations that are sure to aid all women with PCOS such as exercise, reduced carbohydrate diets and lowering exposure to petrochemicals. However, the medical history and specialized testing can be a guide for more specific recommendations.

Functional Testing for PCOS

A nutrients panel test can help determine if there are specific nutritional deficiencies such as low levels of vitamin D, vitamin A and omega-3 fatty acids, which tend to be common in PCOS. A female hormone panel can determine if there are specific imbalances with sex hormones. These imbalances can potentially be corrected with dietary recommendations, bio-identical  hormone replacement, and nutraceutical supplements. Evidence of dysbiosis in gut from a stool analysis can be reversed with dietary recommendations that promote colonization of helpful butyrate producing bacteria. Nutraceuticals containing antibiotic herbs can preferentially kill harmful bacteria while protecting good bacteria. Probiotic supplements containing specific strains of bacteria and prebiotic fibre can be very effective. Food sensitivity testing can help confirm if there are specific foods in the diet that are activating an immune response, causing further inflammation in the gut. Environmental toxin analysis would shed light on high levels of exposure to particular toxins, most of which are known hormone disruptors. Even the simple testing of insulin levels and blood sugar can lead to recommendations for easily accessible compounds like inositol, L-carnitine and chromium which can effectively increase insulin sensitivity.

Conclusions

The take home message is that PCOS is an extremely common and often disruptive condition for a significant amount of women worldwide. The conventional treatment of PCOS often does not provide long term solutions and can have significant side effects. Simple and inexpensive solutions through dietary, supplement and lifestyle recommendations can address the root causes of PCOS and bring about significant symptom relief with long-term sustainability. I therefore encourage anyone suffering from PCOS who hasn’t found an effective solution to contact a local Naturopathic Doctor or Functional Medicine Doctor for an assessment. If you would like to contact me, you can do so through the appointment page by clicking the link in the menu bar. The sooner you start to address the root causes the easier and quicker long lasting symptom relief can be achieved. That being said, implementation of a functional medicine approach to PCOS will undoubtably be helpful at any stage and at any age.


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11/Jul/2022

Fasting for six years

I thought it was a good time for me to personally reflect on the last six years of intermittent fasting. Yes, for the last six years I have been following a relatively strict program of fasting for 16-20 hours of the day. Usually this means having my last meal of the day around 6pm and my first meal the following day at 11am.

I remember first hearing about the benefits of intermittent fasting (IF) at a medical conference organized by the Association for the Advancement of Restorative Medicine back in 2016. After Dr. Denis Wilson M.D. spoke about all the clinically supported benefits of IF as well as his own personal journey with IF, I was sold!

Fasting and Climbing

That was around the same time I started to take rock climbing seriously. A was training 2-3 days per week and for around 2 hours each session. I decided it would be an interesting experiment to combine IF with my morning training. I was hitting the gym while in a fasted state (usually around 16 hours at that point) and would train as hard as I could.

When the body is in a post 14 hour fast it starts to convert fat into an energy source called ketones. This is because all the sugar stored in the body has been used up. Exercising while fasting speeds up this process. I was amazed to see how quickly this combination of fasting and exercise transformed my body and my health. Over the course of a year I lost 15lb and went up several grades in my climbing. My climbing partners couldn’t believe I was able to climb hard on an empty stomach, but I actually felt lighter and clearer. I would try to have my first meal of the day within an hour after workouts for optimal protein metabolism to build muscle. I would regularly get comments from familiar faces at the gym asking if I’m doing anything special outside of the gym. I simply told them that I’m fasting and climbing. Pretty simple but very effective.

Finding the right program

Over the following 5 years I had short 2-3 week periods where I would take a break from IF but would soon return as I felt my best, looked my best and climbed my best while on a pretty strict IF program. I have since recommended IF to dozens of patients, the majority of whom see results within a few months. One of my biggest supporters and now followers of IF is my dad. He saw such dramatic results that IF is now a regular lifestyle habit for him as well.

I dabbled a few times with doing pretty long fasts (20-23 hours) and eating only one meal per day but I found that this was a bit hard on my body. I was getting irritable and was not performing very well at the gym. I now have a pretty good understanding of how many hours my body likes to fast for and how many meals per day is best.

Everyone is going to find a sweet spot for themselves. I don’t recommend forcing the body into a particular program but to try fasting for different lengths of time and see what feels and works best. It does take a little getting used to at first but it is important to remember that this is a very natural state for the human body.

It’s only natural

Through most of human evolution humanity had to go for extended periods of time without food. In fact, an abundance of food at our beck and call is likely contributing to a lot of chronic disease in our modern way of living. Many religious traditions still practice fasting in order to clear the mind, body and spirit. Centuries of cultural practice as well as hundreds of recent studies are in support of fasting in one form or another. It is one of the cheapest, simplest and most effective medical programs I can recommend for a patient.

What lies ahead

Looking ahead to the next decade, I don’t see myself giving up IF anytime soon. There are a few other lifestyle changes I would like to implement but IF will continue to be the backbone of my personal health and wellness program. There are some individuals including in pregnancy where IF is not recommended. I encourage those of you curious about IF or trying it out, to at least have a consultation with a health professional like myself. The benefit of being supervised by a Naturopathic Doctor is the peace of mind that your are practicing something that is safe for your body, you have someone to answer questions as they arise and even to run blood tests if necessary. If I have inspired at least a few people to give IF a try then I have passed along a valuable lifestyle tool as it was passed to me six years ago. Happy fasting everyone!


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06/Jul/2022

What is NAD?

NAD IV therapy was described to me as a “game changer” while I was at a medical conference in Arizona. Up until then I had regularly treated my patients with vitamin and mineral infusions to help restore energy, sleep and manage the physical symptoms of stress amongst other things. I had come to terms with the fact that I could expect about a 60-70% response rate in my patients who were being treated for chronic fatigue. A colleague told me that NAD would be a game changer and that I could expect to see better and more consistent results. After my first NAD patient texted me the following day that they felt like a million dollars, I was sold to the idea.

NAD stands for nicotinamide adenine dinucleotide. It is a coenzyme that our body requires in order to convert food into energy and for facilitating many biochemical reactions. We need NAD to metabolize nutrients, proteins, carbohydrates and fats. NAD also impacts the functioning of cells, formation of muscle and regeneration of tissue. Studies have shown that low NAD levels are detrimental to muscle development, while elevated NAD levels could improve muscle health.

Like many fundamental nutrients and hormones, NAD levels decline as we age. This can prompt changes to our metabolism, energy levels, and our biochemistry over time. Low NAD levels can also make us more susceptible to age-related diseases and health concerns, such as Alzheimer’s, sarcopenia, and inflammation. NAD has even been touted as an anti-aging nutrient.

At my Toronto Naturopathic located in York MIlls,  between the Bayview village area and Leaside, we have started to incorporate NAD into many of our IV infusions. Here are some of the outcomes of NAD therapy backed up by clinical research:

Cognitive dysfunction

Boosting NAD intake can impact brain health by improving neuronal function, protecting brain cells from harm, and driving mitochondrial functioning. Animal studies have shown that a group of signalling proteins called sirtuins may be linked to memory and learning. Sirtuins protect the body from amyloid proteins, which are related to Alzheimer’s and other degenerative diseases. Sirtuin production relies on NAD. Boosting NAD levels may likely help protect the body from amyloid proteins via sirtuin production.

Recovery from substance abuse

Excessive consumption drugs and alcohol can cause damage to organs and tissues including the brain. Studies have shown that substance abuse can specifically cause a drop in NAD levels. NAD is fundamental in the repair and detoxification pathways engaged after consumption of drugs and alcohol. Boosting NAD levels with IV therapy can help with cravings while mitigating brain fog, anxiety and fatigue.

Athletic Recovery

Proper energy metabolism and inflammatory pathways are fundamental in athletic recovery from training and injury. NAD supplementation helps to optimize energy metabolism through mitochondria activity, increases blood flow and reduces inflammation. These benefits in turn help to hasten the recovery phase and lessen muscle pain.

Chronic Fatigue

If you’re struggling with Chronic Fatigue or Myalgic Encephalomyelitis (ME), NAD could offer some alleviation. One of the ways NAD works via the mitochondria is by  boosting the production of ATP. ATP is the primary energy source of all cells in the body.  Boosting NAD levels via IV infusion helps to increase ATP production thereby reducing the severity of chronic fatigue syndromes.

Wondering how you may benefit from NAD supplementation? Give me a call or email and we can discuss how NAD may help you reach your health and wellness goals.


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30/Jun/2022

What is Long Covid?

Long Covid is defined as symptoms that present 12 weeks after infection and that persist for at least 8 weeks. The most common symptoms being: Fatigue, Shortness of Breath and Cognitive Dysfunction. There will be an estimated 150 million cases of Long Covid cases worldwide as of 2022. Long Covid has the potential to significantly impact the lives of a large portion of the population making day to day activities difficult or near impossible. Although there are ways to reduce the risk factors in developing long covid, there aren’t many proven conventional medications to treat Long Covid once symptoms set in.

We now know that viral fragments, lingering spike protein and persistent inflammation are all likely features of Long Covid. This chronic state of immune activation leads to heart and blood vessel abnormalities, lung impairment, neurological injury and autoimmunity. Luckily, functional medicine practitioners have been at the forefront in developing protocols that work to resolve the aftermath of COVID-19 infection.

Mitochondrial Dysfunction

There is evidence of mitochondrial dysfunction in Long Covid cases as seen through disruption in fatty acid oxidation and altered lactate production. This would also partially explain the chronic fatigue of Long Covid. Functional medicine has a long history of developing protocols to address mitochondrial dysfunction. Many of the compounds used have been showing promise in treating Long Covid. For example, there is evidence of reduced levels of Coenzyme Q10 in COVID-19 infection. CoQ10 is an important compound in mitochondrial function and energy production. Supplementing with this compound along with other mitochondrial supportive nutrients (Niacin, N-Acetyl Cysteine, Alpha Lipoic Acid) have been helpful in treating Long COVID associated fatigue.

Chronic Inflammation

We also know that there is a wealth of data to suggest high levels of inflammatory markers in Long Covid sufferers. Conventionally, steroids such as prednisone have been used to effectively treat Long Covid symptoms. However, steroids can not be used indefinitely as there are significant side effects associated with long term usage. In Naturopathic and Functional Medicine we have evidence of a number of naturally derived compounds that work to treat Long Covid associated inflammation including: Curcumin, Resveratrol, Cannabinoids, Luteolin, Omega 3, and Black Cumin.

Immune System Abnormalities

We also know that there is immune system dysfunction in Long Covid as evidenced in abnormal T-cell behaviour. One of the most important compounds regulating immune function is vitamin D. There is strong evidence that having adequate vitamin D status prior to Covid infection is protective toward Long Covid and giving large doses of vitamin D to both active Covid-19 cases and Long Covid sufferers can be therapeutic.

Gastrointestinal Symptoms

Long Covid cases also seem to have a higher incidence of prolonged gastrointestinal symptoms and intestinal dysbiosis with organisms that increase inflammation. One of the best ways to treat intestinal inflammation is by promoting the growth of intestinal organisms that produce the short chain fatty acid Butyrate. Food that is high in fibre typically help to promote beneficial species of intestinal organisms. Oats, Apples, Onions, Asparagus, Broccoli, Whole grains, underripe bananas, Legumes, and Berries are some excellent foods shown to promote butyrate production.

Cannabinoids

Cannabinoids, and more specifically cannabidiol (CBD) has been shown to have some interesting mechanisms in the treatment of Long Covid. Strains of cannabis containing high levels of CBD have been shown to block spike protein from entering the cell (via ACE-2 receptors), modulate ACE-2 receptor density on cell surfaces (less doors of COVID to enter) and reduce inflammation. Therefore cannabinoids are very exciting compounds currently being investigated for use in Long Covid therapy.

Conclusions

Long Covid is a multifaceted chronic disease with effects on various physiological systems. Drugs with a narrow therapeutic scope are not going to be as effective as complex compounds that effect multiple physiological processes at the same time. This type of therapeutic synergy is a hallmark of naturally derived medicines and therefore functional medicine is going to play a pivotal role in dealing with this prevalent and highly complex disease state. In my Toronto practice I have had several cases of long covid that only began to resolve once a functional medicine protocol was put into place. So if you know someone who is suffering from Long Covid I recommend connecting them with a local Naturopathic Doctor or Functional Medicine Practitioner.


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09/May/2022

The mind body connection

The mind and body are closely connected through thousands of chemical messengers. When we have a mental experience the brain sets off a cascade of neurotransmitters and hormones that affects our body. For instance when we experience joy, our body produces the hormone oxytocin. Oxytocin reduces blood pressure, stress hormone, anxiety and promotes growth and healing. Conversely, when we experience an emotion like sadness this can raise stress hormone, increasing blood pressure and eliciting negative effects on the immune system. Psychotherapy can therefore have a big impact on the health of our body by modifying mental outlook and thus inducing positive chemical messengers to the rest our body. An example is cognitive behavioural therapy, which has well documented success in the treatment of depression, anxiety and stress. https://pubmed.ncbi.nlm.nih.gov/ 31004323/

We can also treat conditions of the mind through our body. In pharmaceutical medicine, drugs like anti-depressants can block the breakdown of the neurotransmitter serotonin. Serotonin is involved in mood and therefore in some individuals boosting serotonin activity can improve mood and decrease anxiety. However, some short falls of pharmaceutical medicine is that it can often cause unwanted side effects and have a narrow therapeutic range; meaning that too little may have no effect and too much can be deadly. There are also issues with dependancy and addiction.

On the other hand nutritional and herbal supplementation can be an effective treatment for depression, stress and anxiety without the same safety concerns as drugs.

Supplementation for depression

Depression is both a physical and emotional condition. We know that depression can impact the reproductive system, immune system and our nervous system. Nutritional deficiencies can arise as a result of long standing depression and can be a precursor in the development of a depressive condition. Deficiencies in vitamin B12, vitamin D and protein are associated with depression. https://pubmed.ncbi.nlm.nih.gov/ 23377209/ In my Toronto clinic we can identify and correct nutritional deficiencies and make a big impact on depressive symptoms.

There is also a lot to be said about the impact of chronic inflammation on brain and mental health. Research has shown that chronic inflammation can increase susceptibility to depression. https:// pubmed.ncbi.nlm.nih.gov/32553197/ At the Toronto clinic we treat inflammation using supplements such as curcumin, omega-3 fatty acids and cannabidiol (CBD). These supplements can improve depressive symptoms through modulation of inflammation.

Furthermore many natural health products like CBD can also impact neurotransmitters (brain messenger chemicals) directly associated with depression. Through the interaction of cannabinoid receptors, 5-HT1A (involved in serotonin regulation) and neurogenesis factors CBD can act similarly to an anti-depressant medication but with less potential for adverse effects. At the Toronto clinic I offer cannabis education and counselling when cannabinoids would benefit a patients condition.

Supplementation for Anxiety

Anxiety disorders are the most common mental illness in the United States effecting close to 20% of the population every year. While genetics play a significant role in the development of an anxiety disorder, biological and environmental factors are pivotal as well. We know that there are often disruptions in serotonin and dopamine, cortisol and adrenaline in anxiety syndromes. A common class of drugs used in the treatment of anxiety are the benzodiazepines (Xanax, Valium, Ativan etc…). Although these medications can be very effective, they often have significant side effects (drowsiness, depression, constipation). Benzodiazepines can also be difficult to stop once started. One of the most significant mechanisms in which anti-anxiety medications work is through the GABA receptor system.

GABA is an inhibitory neurotransmitter, meaning that it helps to calm the nervous system and muscular skeletal system. Benzodiazepines have a very strong effect on GABA receptors making them effective but also potentially dangerous.

Many nutraceutical compounds activate the GABA pathway but with a gentler effect than benzodiazepines. Pharma GABA (GABA produced by bacteria), Passionflower, St. Johns Wort, Taurine, 5-HTP and CBD all have well documented effects on GABA and Serotonin. At the Toronto clinic we use these compounds successfully in the treatment of anxiety syndromes with less potential for adverse effects.https://pubmed.ncbi.nlm.nih.gov/ 11679026/

Supplementation for Stress

Every single human being experiences stress throughout their life. Stress can be a healthy natural process in the right circumstances and at the right time. Stress becomes pathological when it is experienced chronically and without appropriate instigation. Long lasting stress can have detrimental effects on multiple biological systems including the immune system, endocrine system (hormones) and cardiovascular system. https:// www.ncbi.nlm.nih.gov/pmc/articles/PMC5137920/

There are no specific pharmaceutical interventions in the treatment of stress. Benzodiazepines are the most common class of drug prescribed for debilitating stress and as I mentioned in the section on anxiety, benzodiazepines can have significant side effects and issues with dependency.

Since there is a wide spectrum of factors that can cause stress a “one size fits all” approach is not always effective. The naturopathic approach is fundamentally holistic and therefore takes into account mental, emotional and physical stressors. For instance a change in work schedule may be contributing to sleep disruption, leading to insomnia, poor work performance and nutritional disruption.

Furthermore, there is an entire class of nutritional and herbal supplements called adaptogens. Adaptogens have the ability to modulate cortisol (stress hormone) preventing peaks and dips in cortisol levels throughout the day. Overtime treatment with adaptogens facilitate a more balanced cortisol output avoiding periods of hyperactivity and burnout. To my knowledge there are no pharmaceutical drugs that act in a similar way. Some common adaptogens are: Ashwagandha, Rodiola and Siberian Ginseng. Vitamins like Vitamin C and Magnesium can help support adrenal function further helping the body to avoid burnout in periods of prolonged stress. At the Toronto clinic I use these adaptogenic compounds in conjunction with other treatments to provide a safe and effective treatment plan for chronic stress.

The mind can be treated through the body. Pharmaceutical interventions can be effective but often come with safety concerns around adverse effects and dependancy. There are many safe and effective natural approaches to mental health conditions through supplementation. At my Toronto clinic we specialize in developing an individualized plan to help achieve your mental health goals.


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13/Apr/2022

Intro

Let’s take a look at 5 of the most common chronic issues that we experience as a a result of modern living: Stress, Insomnia, Anxiety, Depression and Pain. While there are some pharmaceutical medications that can be effective, most individuals would rather seek a safe and effective alternative approach. Here I will outline these conditions individually and describe some of the most effective treatments that I use at my Toronto naturopathic clinic Physic-Logic.

Stress

Stress is an unavoidable biological response to a threat. The human body developed the stress response in order to escape immediately threatening situations like wild animals and hunting for food. The stress response evolutionarily developed to kick the body into high gear in particular situations and for relatively short intervals. Stress demands a lot from our body in order to perform at a very high level. An increased output of hormones, vitamins and minerals are utilized during the stress response.

The reality is that in modern day living we perceive stress from a variety of situations that are outside of our evolutionary makeup. For example, many if not all of us experience financial stress, workplace stress, relationship stress, medical related stress etc… If we do not have effective coping strategies these stressors, overtime, use up our bodies resources and lead to burnout.

Chronic stress can also be a trigger in the development and resurgence of chronic illnesses like autoimmune disease, allergies, gastrointestinal disease, migraine and skin conditions. At our Toronto Naturopathic Clinic we have several therapies that help to support the body through stress. Adaptogenic herbs like Rhodiola and Ashwagandha help to balance cortisol levels, evening out the highs and lows of a stress response. Magnesium, b-vitamins and vitamin C help to support the adrenal glands which can experience a state of fatigue when under prolonged stress. Acupuncture can help to bring the body into a calming parasympathetic state after prolonged periods in sympathetic fight and flight mode. All these holistic modalities work together to bring a patient out of stress induced fatigue while allowing a better more controlled stress response in the future.

Insomnia

One of the most important foundations for health is good sleep. Most adults require 8-10 hours of sleep for optimal performance whereas in reality 5-7 hours seems to be the norm for most many patients. Not only is sleep duration important but quality uninterrupted sleep is important as well. Our body will have trouble healing and functioning optimally without adequate sleep quantity and quality.

There are 3 types of insomnia that I typically see in my Toronto Naturopathic practice: 1. Sleep initiation insomnia (trouble falling asleep) 2. Sleep maintenance insomnia (trouble staying asleep) and 3. A combination of both initiation and maintenance insomnia. Some of the most common issues causing insomnia are due to anxiety, stress, pain and discomfort. Therefore a successful approach to treating insomnia needs to take into consideration the root causes of the insomnia and the type of insomnia.

Many of the pharmaceutical approaches to insomnia have issues with dependency, addiction and grogginess. The pharmaceutical treatments don’t typically consider the issues causing the insomnia or the type of insomnia either. At my Toronto Naturopathic clinic Physio-Logic I use a combination of time tested approaches to pinpoint the specific areas of sleep that have been disrupted. For instance melatonin can be a very effective treatment for insomnia but many patients don’t realize that there is more than one type of melatonin and that dosage is very important. A fast acting sublingual melatonin may be very helpful to initiate sleep but not effective at maintaining sleep throughout the night; whereas a prolonged release melatonin is often much more effective for sleep maintenance issues. Similarly Cannabis and cannabinoids can be used for insomnia but fast acting inhaled forms are better suited for sleep initiation whereas longer acting oral forms are more useful for sleep maintenance. At our Toronto Naturopathic clinic we take into consideration all the nuances in the diagnosis of insomnia to come up with the most effective and safest course of treatment.

Anxiety

Most of us have experienced anxiety at one point or another and like stress, anxiety in specific circumstances and in relatively short durations is perfectly normal. When anxiety becomes a daily or long lasting biological response we simply cannot function optimally and start placing our body at risk of chronic disease.

Stress and anxiety are closely related with anxiety being more of the mental emotional response and stress being more of the physical response to a perceived threat. A big issue with chronic anxiety is that it becomes a vicious cycle perpetuating itself; the experience of anxiety creates more anxiety and the fear of its return creates more anxiety. The brain, much like muscle has a memory and the more times specific pathways are engaged the harder it becomes to break those physiological habits.

Anti-anxiety medications often fail at producing long lasting results without side effects because they where often designed for treating other conditions; as is the case with anti-depressant medications. A recent breakthrough in anxiety medicine has revealed that our endocannabinoid system has a significant role in the maintenance of balanced mental emotional health. Therefore compounds like cannabidiol (CBD) which act to support the endocannabinoid system have been shown to be effective and safe in the treatment of anxiety with minimal side effects.

Promotion of a healthy lifestyle including daily exercise and a healthy diet can further support the endocannabinoid system and are therefore extremely effective strategies in their own rite. At my Toronto Naturopathic Clinic Physio-Logic we combine several strategies including cannabinoid education to formulate an effective strategy to break the anxiety cycle once and for all.

Depression

Depression is a spectrum ranging from mild symptoms to severe symptoms. While pharmaceutical medication is often necessary for more severe forms of depression, functional medicine can be very effective in treating mild to moderate depression.

Most anti-depressant medications work by keeping higher levels of serotonin in the brain and nervous system. There are many natural compounds that can achieve similar results with a less specific but more holistic mode of action. The net effect is something that is gentler than a pharmaceutical drug but with less potential for dependency and side effects. One example is the flower St. Johns Wort which s backed by several studies confirming its efficacy in treating mild to moderate forms of depression.

Nutrition and exercise are also fundamental in treating all forms of depression and unfortunately as symptoms get worse so do the potential for lassitude and malnourishment. Intervention at the early stages of depression can often allow the patient to utilize holistic therapies effectively and prevent the need for a more aggressive pharmaceutical approach. At my Toronto Naturopathic Clinic, we use functional and holistic medicines from both eastern western medical traditions to treat mild to moderate depression safely and effectively. Some of these treatments include: herbal therapy, acupuncture, intravenous therapy and lifestyle counselling.

Pain

One of the biggest obstacles to cure is pain. Chronic pain interfere with the activities of daily living, disrupting sleep and making exercise impossible. Chronic pain also places physical stress on the body, over time leading to physical burnout and deficiency. Unfortunately many of the most effective pharmaceutical strategies for pain management are linked to addiction and long term side effects. Gastritis (inflammation of the stomach) is a common condition I see in practice linked to long term use of Non steroidal anti-inflammatory medications like Advil and Naproxen. Fortunately there are many safe and effective treatment options within naturopathic and functional medicine.

Pain is often linked to a few common phenomena: lack of circulation, inflammation, tight muscles and neurological injury. Many holistic treatments such as acupuncture, cupping, moxibustion, laser therapy and massage work to improve circulation and loosen tight muscles. Many vitamin, mineral and herbal therapies are excellent for controlling inflammation. Curcumin is a compound derived from the spice turmeric and has years of scientific research demonstrating its strong anti-inflammatory properties without side effects. Using electric current in conjunction with acupuncture can be a safe and very effective treatment for neurological injury. At the my Toronto Naturopathic clinic we utilize many different tools and strategies to provide a safe, effective and individualize treatment for both acute and chronic pain.

Conclusion

Many of the health concerns that we experience in modern society can be safely and effectively treated with a Naturopathic approach. I would encourage anyone experiencing stress, insomnia, anxiety, depression or pain to have a consultation with a Naturopath or other functional medicine doctor. Unfortunately it is all too common for patients to first step into my office after years of trying to manage symptoms using only a pharmaceutical approach. It is never too late to try a more holistic approach. You will be surprised at how effective these treatments can be.


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03/Mar/2022

For the past 6-months I have been supplementing with collagen peptides in my morning coffee. I take relatively few daily supplements; Lions Mane mushroom for my brain, Vitamin D for my immune system and Collagen Peptides for my joints. I became focused on protecting my joints (especially my fingers, toes, knees and shoulders) a few years ago as I started training harder in rock climbing. I began to feel stiffness, soreness and occasionally pain after hard training sessions. I decided I needed to do something soon or I would lose the ability to climb at a relatively young age.

Instead of suppressing inflammation with compounds like curcumin, glucosamine and chondroitin I wondered if it would be possible to actually strengthen my tendons and ligaments. I had been aware of collagen supplementation through a number of patients taking it for hair and skin health. I had largely dismissed collagen as a beauty supplement and it was therefore not on my radar as a potential athletic enhancement.

Just over 6-months ago I had received a newsletter about of tendon health for climbers. The physiotherapist/climbing expert outlined specific exercises for warming up fingers and also mentioned the benefits of collagen supplementation for tendon health. At that moment I decided to re-visit the research on collagen, and I am glad I did!

Collagen peptides are small amino acid chains derived from collagen, which is the primary structural protein in ligaments, tendons, bones and skin. The research behind supplementing with collagen peptides seems to support three key areas.

Skin

A few studies, including randomized placebo controlled trials, have shown an improvement in skin moisture, elasticity and wrinkles with daily supplementation of Collagen Peptides. The daily dose ranged from 4-10 grams daily.

Osteoarthritis

Several studies have demonstrated a modest benefit in pain and function with daily supplementation of Collagen Peptides. Most studies focused on osteoarthritis (OA) in the knees but a couple also mention hip and hand. In general the improvement was modest (a little better than chondroitin) and took approximately 3-5 months to appear. Some studies used collagen peptides in combination with other compounds like chondroitin and hyaluronic acid. Most studies used a 10 gram daily dose.

Performance Enhancement

A great systematic review came out in 2021 that looked at the effects of collagen peptide supplementation on body composition, collagen synthesis and recovery from joint injury.

Five studies demonstrated a positive effect on reducing joint discomfort, knee pain , ankle and knee function and recovery from achilles tendinopathy. Those studies used 40 mg-10 grams per day over a 4-6 month period.

Four studies looked at the effects of collagen supplementation on body composition and muscle strength. The studies combined collagen supplementation (15 grams per day for 3-months) with resistance training.The studies, which were conducted on elderly men, active men and untrained pre-menopausal women, found an increase in fat free mass, a decrease in body fat percentage and an increase in hand grip strength.

Two studies assessed the effect of collagen supplementation on exercise performance and recovery from muscle soreness. The studies included recreationally active men, one used 3 grams per day for 6 weeks and the other used 20 grams per day for 7 days prior to intense exercise. There was a strong positive effect on pain with movement and muscle soreness.

Two studies assessed the effects of Collagen peptide supplementation on collagen synthesis. When taken 60min prior to exercise there was a significant increase in collagen synthesis markers following ingestion of 15 grams collagen enriched with vitamin C.

Conclusions

When it comes to preserving joint, ligament and tendon health for myself and my patients, collagen peptide supplementation is now a staple. The evidence in favour of collagen, along with a strong safety profile makes collagen peptides a valuable nutritional supplement in both sports medicine and anti-aging medicine. The recommended dose seems to be between 10-20 grams per day for 3-6 months.

References

Inoue N, Sugihara F, Wang X. Ingestion of bioactive collagen hydrolysates enhance facial skin moisture and elasticity and reduce facial ageing signs in a randomised double-blind placebo-controlled clinical study. J Sci Food Agric. 2016;96(12):4077-81.

Czajka A, Kania EM, Genovese L, et al. Daily oral supplementation with collagen peptides combined with vitamins and other bioactive compounds improves skin elasticity and has a beneficial effect on joint and general wellbeing. Nutr Res 2018;57:97-108.

Asserin J, Lati E, Shioya T, Prawitt J. The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials. J Cosmet Dermatol. 2015;14(4):291-301

Sangsuwan W, Asawanonda P. Four-weeks daily intake of oral collagen hydrolysate results in improved skin elasticity, especially in sun-exposed areas: a randomized, double-blind, placebo-controlled trial. J Dermatolog Treat. 2020:1-6.

Benito-Ruiz P, Camacho-Zambrano MM, Carrillo-Arcentales JN, et al. A randomized controlled trial on the efficacy and safety of a food ingredient, collagen hydrolysate, for improving joint comfort. Int J Food Sci Nutr. 2009;60 Suppl 2:99-113.

Kumar S, Sugihara F, Suzuki K, Inoue N, Venkateswarathirukumara S. A double-blind, placebo-controlled, randomised, clinical study on the effectiveness of collagen peptide on osteoarthritis. J Sci Food Agric. 2015;95(4):702-7.

Trc T, Bohmová J. Efficacy and tolerance of enzymatic hydrolysed collagen (EHC) vs. glucosamine sulphate (GS) in the treatment of knee osteoarthritis (KOA). Int Orthop. 2011;35(3):341-8

Moskowitz RW. Role of collagen hydrolysate in bone and joint disease.Semin Arthritis Rheum 2000;30:87-99

Kalman DS, Schwartz HI, Pachon J, Sheldon E, Almada AL. A randomized double blind clinical pilot trial evaluating the safety and efficacy of hydrolyzed collagen type II in adults with osteoarthritis. FASEB Experimental Biology 2004 Abstracts, Washington DC, April 17-21, 2004; A90.

Amino Acids. 2021; 53(10): 1493–1506.Published online 2021 Sep 7. doi: 10.1007/s00726-021-03072-xPMCID: PMC8521576PMID: 34491424The effects of collagen peptide supplementation on body composition, collagen synthesis, and recovery from joint injury and exercise: a systematic review Mishti Khatri,1 Robert J. Naughton,1 Tom Clifford,2 Liam D. Harper, 1 and Liam Corr1


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Patient focused integrative health care. Utilizing effective natural approaches designed to be used alone or to compliment conventional medical care.


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