Diabetes Archives

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10/Jun/2024

Diabetes is a chronic condition that affects millions of people worldwide, prompting many to seek effective treatments to manage their blood glucose levels. Among the numerous pharmaceutical options available, Ozempic has garnered significant attention. While this medication has proven benefits, it’s essential to explore its use from a naturopathic perspective to understand how it fits into a holistic approach to diabetes management.

What is Ozempic?

Ozempic is a brand name for semaglutide, a medication approved by the FDA for the treatment of type 2 diabetes. It belongs to a class of drugs called GLP-1 receptor agonists, which work by mimicking the incretin hormones that the body usually produces naturally to stimulate insulin secretion in response to meals. By enhancing insulin production, Ozempic helps to lower blood sugar levels effectively.

How Does Ozempic Work?

Ozempic works through several mechanisms:

Stimulating Insulin Secretion: It enhances the release of insulin from the pancreas when blood sugar levels are elevated.
Inhibiting Glucagon Release: It reduces the secretion of glucagon, a hormone that increases blood sugar levels.
Slowing Gastric Emptying: It delays stomach emptying, which helps control post-meal blood sugar spikes.
Promoting Satiety: It can help reduce appetite, which may lead to weight loss.

The Benefits of Ozempic

For many individuals with type 2 diabetes, Ozempic offers numerous benefits:

Effective Blood Sugar Control: Clinical trials have demonstrated that Ozempic significantly lowers HbA1c levels.
Weight Loss: Many patients experience weight loss while taking Ozempic, which is beneficial for those with type 2 diabetes.
Cardiovascular Benefits: Some studies suggest that Ozempic may reduce the risk of major cardiovascular events in people with type 2 diabetes.

Naturopathic Principles and Diabetes Management

Naturopathy emphasizes the body’s innate ability to heal itself through natural means. This holistic approach to health focuses on treating the root cause of diseases rather than just the symptoms. Naturopathic treatments often include lifestyle modifications, dietary changes, herbal remedies, and stress management techniques.

Combining Ozempic with Naturopathic Methods

While Ozempic offers significant benefits, integrating it with naturopathic principles can lead to a more comprehensive diabetes management plan. Here’s how:

1. Diet and Nutrition

Low Glycemic Diet: Incorporating foods with a low glycemic index can help stabilize blood sugar levels. Focus on whole grains, vegetables, lean proteins, and healthy fats.
Anti-inflammatory Foods: Foods rich in omega-3 fatty acids, such as fish, flaxseeds, and walnuts, can help reduce inflammation, which is often elevated in individuals with diabetes.
Herbal Supplements: Herbs like cinnamon, fenugreek, and berberine have shown potential in managing blood sugar levels. Always consult with a healthcare provider before adding supplements to your routine.

2. Physical Activity

Regular Exercise: Engaging in regular physical activity, such as walking, swimming, or yoga, can improve insulin sensitivity and overall metabolic health.
Strength Training: Incorporating strength training exercises can help build muscle mass, which in turn improves glucose uptake by cells.

3. Stress Management

Mindfulness and Meditation: Practices like mindfulness meditation, deep breathing exercises, and progressive muscle relaxation can help reduce stress levels, which can positively impact blood sugar control.
Adequate Sleep: Ensuring sufficient and quality sleep is crucial, as poor sleep can negatively affect insulin sensitivity and glucose metabolism.

4. Regular Monitoring and Consultation

Blood Sugar Monitoring: Regularly monitoring blood sugar levels can help individuals understand how their lifestyle choices and medications affect their diabetes management.
Consultation with Healthcare Providers: Working closely with both conventional healthcare providers and naturopathic practitioners can create a balanced and personalized treatment plan.

The Role of Naturopathy in Enhancing the Efficacy of Ozempic

By incorporating naturopathic practices, individuals can enhance the efficacy of Ozempic and achieve better overall health outcomes. A holistic approach ensures that all aspects of health—physical, emotional, and mental—are addressed, providing a more comprehensive treatment for diabetes.

Potential Synergies

Improved Insulin Sensitivity: Lifestyle changes such as diet and exercise can improve insulin sensitivity, potentially reducing the dosage of Ozempic needed over time.
Weight Management: Combining Ozempic with a healthy diet and regular exercise can enhance weight loss efforts, further improving diabetes management.
Enhanced Well-being: Addressing stress and mental health can lead to better overall well-being, which is crucial for long-term disease management.

Potential dangers of Ozempic; can Naturopathy help?

Common side effects of Ozempic include gastrointestinal issues like nausea, vomiting, and diarrhea. Additionally, there are concerns about more severe complications such as pancreatitis, kidney problems, and thyroid tumours.

To offset some of these adverse effects, naturopathic medicine offers alternative and complementary approaches. For instance, incorporating herbal remedies like ginger and peppermint can help soothe digestive discomfort, while dietary adjustments rich in anti-inflammatory foods can support overall well-being. Supplements such as probiotics may also aid in maintaining gut health. By integrating these naturopathic strategies, individuals on Ozempic can potentially mitigate some of the drug’s side effects, promoting a more balanced and holistic approach to their health management.

Conclusion

Ozempic represents a powerful tool in the management of type 2 diabetes, offering significant benefits in terms of blood sugar control and weight loss. However, adopting a naturopathic perspective can provide a more holistic approach, addressing the root causes of diabetes and promoting overall health and well-being.

By integrating Ozempic with naturopathic principles, individuals can create a balanced and comprehensive diabetes management plan. This fusion of conventional and natural medicine can lead to improved outcomes, providing a path toward healthier living for those managing type 2 diabetes.

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If you’re looking to explore a holistic approach to diabetes management, consider consulting with a naturopathic practitioner. They can provide personalized guidance and support, helping you integrate natural therapies with conventional treatments like Ozempic.

Your journey to better health starts today. Embrace the possibilities of a balanced approach and take control of your diabetes management with confidence.

Click here to book a free 15min consultation

DoctorShawn

20/May/2024

Ensuring optimal health and wellness requires a proactive approach. As a healthcare provider, I always recommend a series of comprehensive tests and panels for all new patients. These tests offer invaluable insights into various aspects of your health, enabling personalized care and early detection of potential issues. Here are my top five recommended tests and panels:

1. LifeLabs: Enhanced Healthy Living Assessment Panel

Overview:

The Enhanced Healthy Living Assessment Panel from LifeLabs is a comprehensive screening tool designed to offer a holistic view of your overall health. It includes a broad spectrum of tests that evaluate critical factors such as blood glucose levels, cholesterol, liver function, kidney function, and more.

Why It’s Crucial:

This panel serves as a foundational health check, identifying any imbalances or abnormalities that could affect your long-term wellness. By getting a detailed snapshot of various biomarkers, we can tailor a health plan specifically designed for your needs.

What It Tests For:

Complete Blood Count (CBC)
Lipid Profile (Cholesterol, LDL, HDL, Triglycerides)
Liver Function Tests (ALT, AST, ALP, Bilirubin)
Kidney Function (Creatinine, eGFR)
Blood Glucose Levels
Vitamin D
Vitamin B12

Benefits:

Early detection of health issues
Comprehensive understanding of your current health status
Benchmark data for future comparisons

2. LifeLabs: Female/Male Hormone Panel

Overview:

Hormones play a pivotal role in regulating numerous bodily functions, including metabolism, reproductive health, and mood. The Female/Male Hormone Panel from LifeLabs is designed to assess hormone levels, helping to identify imbalances that could be affecting your health.

Why It’s Crucial:

Hormonal imbalances can lead to a variety of health issues, including fatigue, weight gain, mood swings, and fertility problems. This panel provides a detailed analysis of key hormones, enabling targeted interventions that can help restore balance.

What It Tests For:

Testosterone
Estrogen (Estradiol)
Progesterone
Cortisol
Thyroid-Stimulating Hormone (TSH)

Benefits:

Identification of hormonal imbalances
Personalized treatment plans for hormonal health
Improved overall well-being

3. RMA: Food Sensitivity IgG Panel

Overview:

The Food Sensitivity IgG Panel from Rocky Mountain Analytical (RMA) tests for IgG antibodies to identify potential food sensitivities. Unlike immediate allergic reactions (IgE), IgG-mediated reactions can cause delayed symptoms, making them harder to pinpoint.

Why It’s Crucial:

Food sensitivities can lead to chronic inflammation, digestive issues, and other health problems. Identifying and eliminating trigger foods can significantly improve your quality of life and alleviate a range of symptoms.

What It Tests For:

Over 200 common foods, including dairy, grains, nuts, fruits, and vegetables

Benefits:

Identification of trigger foods causing adverse reactions
Alleviation of chronic symptoms like bloating, headaches, and fatigue
Enhanced digestive health and overall well-being

4. LifeLabs: Apolipoprotein B

Overview:

Apolipoprotein B (ApoB) is a protein involved in lipid metabolism and is a key marker for cardiovascular risk. Elevated ApoB levels are associated with an increased risk of atherosclerosis and heart disease.

Why It’s Crucial:

Traditional lipid profiles may not provide a complete picture of cardiovascular risk. Measuring ApoB offers a more accurate assessment, particularly for individuals with normal LDL cholesterol but still at risk for heart disease.

What It Tests For:

Apolipoprotein B levels

Benefits:

More accurate cardiovascular risk assessment
Personalized strategies for heart disease prevention
Improved cardiovascular health

5. Mosaic Diagnostics: Organic Acids Test

Overview:

The Organic Acids Test (OAT) from Mosaic Diagnostics examines metabolic byproducts in urine, offering insights into various aspects of your health, including mitochondrial function, neurotransmitter levels, and gut health.

Why It’s Crucial:

OAT provides a comprehensive overview of metabolic health, identifying issues that might not be apparent through traditional blood tests. It can uncover underlying factors contributing to chronic conditions, fatigue, and mood disorders.

What It Tests For:

Metabolic markers
Neurotransmitter metabolites
Gut dysbiosis markers
Vitamin and mineral deficiencies

Benefits:

Identification of metabolic imbalances
Tailored nutritional and lifestyle interventions
Enhanced energy levels and mental clarity

Conclusion

These top five tests and panels offer a thorough examination of key health areas, providing a solid foundation for personalized care. By investing in these assessments, you are taking proactive steps toward achieving optimal health and well-being.

Ready to take control of your health? Schedule your tests today and embark on a journey toward a healthier, happier you. Feel free to reach out if you have any questions or need further guidance.

Call to Action

For more information or to book your tests, contact us at s.meirovici@physio-logic.com or call 416-490-8243 . Your health is our priority!

DoctorShawn

10/May/2024

In today’s whirlwind of supplements and health trends, Ashwagandha stands out—not as a newfound secret, but as an ancient remedy reasserting its relevance. This powerful herb, rooted in over 3,000 years of Ayurvedic tradition, is making waves among health enthusiasts, wellness seekers, and the fitness community. But what exactly is Ashwagandha, and who stands to benefit from its inclusion in their wellness regimen? This blog dives deep into the world of Ashwagandha, illustrating its history, health benefits, and key considerations for use.

Introduction to Ashwagandha: Origin, History, and Traditional Uses

Ashwagandha (Withania somnifera), also known as Indian ginseng or winter cherry, is a small, shrubby plant native to India and North Africa. Its roots and orange-red fruit have been used for millennia to concoct remedies for a vast array of ailments. Historically revered in Ayurvedic medicine as a Rasayana (tonic), it was prescribed to help people strengthen their immune system after an illness and to enhance longevity.

The Science Behind Ashwagandha: Key Research Findings and Health Benefits

Far from folklore, the benefits of Ashwagandha are now being corroborated by science. Studies suggest that it can reduce cortisol levels, combat stress, improve sleep quality, and boost brain function.

Stress and Anxiety: Ashwagandha’s most praised benefit is its ability to lower stress. This is credited to its classification as an adaptogen, meaning it can help the body manage stress.
Cognitive Function: Research indicates that Ashwagandha supports memory, cognitive speed, and overall brain health.
Physical Performance: Fitness enthusiasts might find Ashwagandha particularly appealing. Some studies show it can enhance strength, muscle size, and recovery.

Who Could Benefit from Ashwagandha?

Given its broad range of benefits, a wide array of individuals can reap rewards from this ancient herb:

The Overwhelmed: Anyone battling the stresses and strains of modern life may find a natural ally in Ashwagandha.
Fitness Aficionados: Athletes and regular gym-goers could experience improved strength and better recovery times.
Sleep Seekers: Those chasing a good night’s sleep might find solace in Ashwagandha’s ability to improve sleep quality.
The Intellectually Engaged: Individuals needing a cognitive boost—whether for studies, work, or personal projects—may benefit from Ashwagandha’s brain function support.

Different Forms of Ashwagandha

Ashwagandha comes in various forms—each with its unique benefits:

Pills: Convenient for those on the go.
Powders: Offers flexibility in how you consume it—mixable in shakes, foods, etc.
Tinctures: Liquid form can be more quickly absorbed by the body.

General Dosage Recommendations Based on Research

For Stress and Anxiety Reduction:

Studies have used dosages ranging from 300 mg to 500 mg of ashwagandha root extract taken twice daily. This dosage range has been shown to effectively reduce stress and anxiety levels in adults.

For Enhancing Sleep:

A dosage of around 300 mg of ashwagandha root extract, taken twice daily, including once just before bedtime, has been observed to improve sleep quality and help manage insomnia.

For Improved Cognitive Function:

Research suggests that 300 mg of ashwagandha root extract twice daily can support cognitive function, memory, and reaction times.

For Athletic Performance:

Doses ranging from 500 mg to 1250 mg of ashwagandha root extract per day have been studied for their effects on muscle strength and recovery in athletes, showing positive outcomes.

General Wellbeing:

For overall health and vitality, a daily dose of 300-500 mg of ashwagandha extract is commonly recommended, though some benefits have been seen with doses up to 6000 mg per day of the powder form, divided into several doses.

Considerations and Safety

Form Matters: The concentration of withanolides, the active compounds in ashwagandha, can differ significantly between products, affecting the dosage. Extracts are more concentrated than powders, requiring smaller doses to achieve similar effects.
Individual Differences: Age, health status, and the presence of specific health conditions can influence the appropriate dosage. What works for one person might not work for another.
Start Small: When beginning ashwagandha, it’s often recommended to start with a lower dose to assess tolerance before gradually increasing to the desired therapeutic dose.
Consult a Professional: Before adding ashwagandha to your regimen, especially if you are pregnant, breastfeeding, have a medical condition, or are taking medication, consult a healthcare provider.

Conclusion

Ashwagandha’s resurgence in the health and wellness domain is no surprise. With its rich Ayurvedic legacy and the backing of modern science, it offers a holistic approach to combatting stress, improving health, and enhancing quality of life. Whether you’re navigating the challenges of modern living, seeking to optimize your physical performance, or in pursuit of mental clarity, Ashwagandha may just be the supplement to explore. We encourage you to consider its potential and, as always, advocate for a conversation with your healthcare provider to ensure it’s the right fit for your health profile and wellness goals.

For more articles on performance enhancing supplements Click Here

For more information on Ashwagandha as well as links to some of the recent research Click Here

DoctorShawn

08/Apr/2024

Our bodies operate on an internal clock that regulates various physiological processes across a 24-hour cycle, influencing everything from our sleep patterns to the way we metabolize food. This internal clock, known as the circadian rhythm, is crucial to our overall health and wellbeing.

In this in-depth exploration, we will uncover the scientific insights on how circadian rhythms affect both our physical and mental health. Whether you’re a health aficionado, a wellness constructor, or simply a lover of science, this narrative around the hidden power of your body’s clock will inform, intrigue, and possibly transform your daily routine.

The Blueprint of a Circadian Rhythm

Circadian Rhythms Unveiled

The word “circadian” comes from the Latin words “circa” (around) and “diem” (day), indicating that these are rhythms that follow a roughly 24-hour day-night cycle. They are endogenously generated, but are affected by external cues, most notably light and darkness.

The Body’s Internal Clockwork

Circadian rhythms are more than just timers; they are a fundamental element woven into the fabric of our existence, directing the ebb and flow of multiple body functions throughout the day. The suprachiasmatic nucleus in the hypothalamus is the hub for this internal clock, which orchestrates a complex symphony of hormone releases, body temperatures, and cellular activities.

See a video featuring Dr. Sachin Panda PhD on how the circadian affects our metabolic health

The Sleep-Health Connection

Navigating The Sleep-Wake Cycle

The circadian clock is intricately linked to the sleep-wake cycle, and the hormone melatonin is the conductor of this symphony. Melatonin levels typically increase in the late afternoon and peak in the early hours of the morning, preparing the body for sleep. Conversely, cortisol, the so-called stress hormone, peaks in the morning, awakening the body and getting it ready for the day.

The Significance of Sleep Consistency

Irregular sleep patterns can disrupt the circadian system, leading to issues like insomnia, sleep apnea, or even sleep phase disorders. These interruptions not only impact sleep quantity but also the quality of our rest, which is arguably the foundation of good health.

Impact on Physical Well-being

Balancing The Metabolic Scales

Circadian rhythms are essential for metabolic function, influencing the peaks and troughs of hunger, the breakdown of nutrients, and the regulation of glucose levels. Disruptions to these rhythms can lead to an increased risk of metabolic disorders, weight gain, and even obesity.

The Immune System Dance

The time-keeping system of the body also holds sway over the immune system, regulating the release of immune cells at the most effective times. When we are not in sync with our internal clock, our immune defences may operate at suboptimal levels, leading to greater susceptibility to infections and inflammatory conditions.

Influence on Mental Health and Cognition

Dawn and Dusk of Mood Disorders

Circadian disruptions have been strongly associated with mood disorders, such as depression and bipolar disorder. The causality may be bi-directional; mental health influences circadian rhythms, and vice versa. When these rhythms go awry, it often leads to disturbances in the hormone balance and neural networks that are critical to mood stabilization.

Cognitive Harmony

Circadian rhythms also impact cognitive function and our ability to concentrate, reason, and recall information. It’s no wonder that instances of cognitive impairment are often linked to individuals who work against their natural sleep-wake patterns.

Aligning with Your Body’s Clock

The Art of Circadian Synchronization

Incorporating circadian-awareness into your daily routine can yield profound benefits to your health. This involves understanding your body’s natural energy peaks and planning high-focus work or exercise during these times, and restful activities during your internal lull periods.

The Sleep Sanctuary Creation

Creating a sleep sanctuary that resonates with the circadian system can significantly improve sleep quality. This includes dimming the lights and reducing screen time before bed, keeping the sleeping environment cool and dark, and establishing consistent sleep and wake times.

Navigating Modern Lifestyle Challenges

The Modern Dilemma of Disrupted Rhythms

Our modern way of life can significantly disrupt the natural circadian rhythms. The scourge of evening screen time, late-night work shifts, and even intercontinental travel can throw our internal clock for a loop, leading to a range of health problems.

Strategies for Resetting

If you find that your circadian rhythms are out of sync, there are strategies you can use to help readjust your body’s clock. These include exposure to bright light in the morning, maintaining a consistent sleep schedule, and employing relaxation techniques in the evening.

Conclusion: A Harmonious Life with Circadian Rhythms

Our understanding of circadian rhythms is continually evolving, but what remains clear is their central role in maintaining health and fostering well-being. By respecting and aligning our lifestyles with these natural cycles, we stand to gain a treasure trove of benefits that extend far beyond the boundaries of our internal clock.

The science speaks for itself. It’s time to listen to our bodies’ whispers and work with, not against, our circadian rhythms. Whether it’s ensuring restful sleep, fine-tuning our metabolisms, guarding our mental fortitude, or honing our daily existence for maximum health, the circadian rhythm is a symphony worth fostering.

Now is your chance to make deliberate choices that honour your circadian system. It might just be the life rhythm that outlasts the test of time.

Learn about “BodyCloc” a supplement that I helped developed designed to work with your Circadian Rhythm

DoctorShawn

30/May/2023

Berberine and Ozempic are two medicines that have gained popularity in recently. Berberine is a natural supplement, while Ozempic is a prescription drug. Both have been shown to lower blood sugar and improve insulin sensitivity, making them popular among people with diabetes and weight loss. In this blog post, we will explore the similarities and differences between these two medicines.

1. What is Berberine?

Berberine is a remarkable natural compound, has been used for centuries in traditional Chinese and Ayurvedic medicine to treat a variety of ailments. Extracted from the roots, rhizomes, and stem bark of plants like goldenseal, Oregon grape, and barberry, berberine’s vibrant yellow color and impressive therapeutic properties have made it a prized ingredient in ancient healing practices.

The mechanism of action for berberine is quite fascinating. It functions by activating an enzyme called AMP-activated protein kinase (AMPK), which plays a critical role in regulating metabolism and maintaining cellular energy homeostasis. This activation leads to numerous health benefits, including improved insulin sensitivity, reduced inflammation, and enhanced lipid metabolism.

Recent scientific studies have confirmed berberine’s effectiveness in managing several conditions. One of its most notable applications is in treating type 2 diabetes, where it has exhibited remarkable potential in lowering blood sugar levels, comparable to the widely prescribed drug metformin. Additionally, berberine has demonstrated promising results in improving cardiovascular health by reducing cholesterol and triglyceride levels. It has also displayed antimicrobial properties against various bacteria, fungi, and parasites, making it a valuable ally in combating infections.

2. What is Ozempic?

Ozempic, also known as semaglutide, is a groundbreaking medication that has taken the world of diabetes management by storm. Developed by Novo Nordisk, Ozempic was approved by the US Food and Drug Administration (FDA) in 2017 for the treatment of type 2 diabetes in adults (FDA, 2017). This innovative drug belongs to a class of medications called glucagon-like peptide-1 (GLP-1) receptor agonists, which are designed to mimic the action of GLP-1, a naturally occurring hormone involved in regulating blood sugar levels.

The mechanism of action for Ozempic is truly fascinating. As a GLP-1 receptor agonist, it works by stimulating insulin secretion from pancreatic beta cells when blood sugar levels are high, thus helping to lower glucose levels in the bloodstream. Moreover, it suppresses the release of glucagon, a hormone that raises blood sugar levels, and slows down gastric emptying, resulting in a decrease in appetite and caloric intake.

Clinical trials have demonstrated Ozempic’s effectiveness in managing type 2 diabetes, showing significant reductions in HbA1c levels (a measure of long-term blood sugar control) and body weight. Additionally, it has been proven to reduce the risk of major cardiovascular events, such as heart attack and stroke, in patients with type 2 diabetes and established cardiovascular disease. With its promising results and innovative mechanism of action, Ozempic has emerged as a powerful tool in the ongoing battle against diabetes and its complications.

3. How does Berberine compare to Ozempic?

In terms of blood sugar regulation, berberine has been shown to lower blood glucose levels by activating AMP-activated protein kinase (AMPK), which helps improve insulin sensitivity and decrease insulin resistance. On the other hand, Ozempic mimics the action of GLP-1, stimulating insulin secretion from pancreatic beta cells when blood sugar levels are high, suppressing glucagon release, and slowing gastric emptying . Both compounds have demonstrated significant reductions in HbA1c levels, a measure of long-term blood sugar control, in patients with type 2 diabetes).

When it comes to weight loss, both berberine and Ozempic have shown promising results. Berberine’s activation of AMPK leads to enhanced lipid metabolism, contributing to weight loss (Turner et al., 2008). Ozempic’s effect on weight loss can be attributed to its ability to slow gastric emptying, resulting in reduced appetite and caloric intake. Clinical trials have demonstrated significant weight loss in patients with type 2 diabetes treated with either compound.

While both berberine and Ozempic have proven effective in managing blood sugar levels and promoting weight loss, their mechanisms of action differ, and they belong to different classes of compounds. Berberine is a natural compound with a broader range of applications, including antimicrobial and anti-inflammatory properties. Ozempic, as a synthetic GLP-1 receptor agonist, has been specifically developed for type 2 diabetes treatment and has demonstrated additional cardiovascular benefits in patients with established cardiovascular disease.

4. Can Berberine and Ozempic be taken together?

It is not advisable to take Berberine and Ozempic together without consulting a doctor. Both medicines can lower blood sugar levels, and taking them together can lead to hypoglycemia (low blood sugar). If you are already taking Ozempic, it is crucial to monitor your blood sugar levels regularly and follow your doctor’s advice on adjusting your medication.

5. Which one should you choose?

Generally, Berberine is a safer and more affordable option compared to Ozempic, especially for people with mild to moderate blood sugar problems. However, for people with severe diabetes or other health complications, Ozempic may be the better choice, as it is a more potent and targeted medication. Ultimately, the decision to use Berberine or Ozempic should be made in consultation with a physician or naturopathic doctor, who can assess your particular health needs and goals.

References:

Imanshahidi, M., & Hosseinzadeh, H. (2016). Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine. Phytotherapy Research, 22(8), 999-1012.

Turner, N., Li, J. Y., Gosby, A., To, S. W. C., Cheng, Z., Miyoshi, H., … & Xu, A. (2008). Berberine and its more biologically available derivative, dihydroberberine, inhibit mitochondrial respiratory complex I: a mechanism for the action of berberine to activate AMP-activated protein kinase and improve insulin action. Diabetes, 57(5), 1414-1418.

Yin, J., Xing, H., & Ye, J. (2008). Efficacy of berberine in patients with type 2 diabetes mellitus. Metabolism, 57(5), 712-717.

Zhang, Y., Li, X., Zou, D., Liu, W., Yang, J., Zhu, N., … & Gong, H. (2008). Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine. The Journal of Clinical Endocrinology & Metabolism, 93(7), 2559-2565.

Imanshahidi, M., & Hosseinzadeh, H. (2010). Berberis Vulgaris and Berberine: An Update Review. Phytotherapy Research, 22(11), 1485-1494.

FDA. (2017). FDA approves new drug to treat type 2 diabetes. Retrieved from https://www.fda.gov/news-events/press-announcements/fda-approves-new-drug-treat-type-2-diabetes

Aroda, V. R., Bain, S. C., Cariou, B., Piletic, M., Rose, L., Axelsen, M., … & Marre, M. (2017). Efficacy and safety of once-weekly semaglutide versus once-daily sitagliptin as an add-on to metformin, thiazolidinediones, or both, in patients with type 2 diabetes (SUSTAIN 2): a 56-week, double-blind, phase 3a, randomised trial. The Lancet Diabetes & Endocrinology, 5(5), 341-354.

Nauck, M. A., Petrie, J. R., Sesti, G., Mannucci, E., Courrèges, J. P., Lindegaard, M. L., … & Madsbad, S. (2016). A phase 2, randomized, dose-finding study of the novel once-weekly human GLP-1 analog, semaglutide, compared with placebo and open-label liraglutide in patients with type 2 diabetes. Diabetes Care, 39(2), 231-241.

Pratley, R. E., Amod, A., Hoff, S. T., Kadowaki, T., Lingvay, I., Nauck, M., … & Soska, V. (2018). Oral semaglutide versus subcutaneous liraglutide and placebo in type 2 diabetes (PIONEER 4): a randomised, double-blind, phase 3a trial. The Lancet, 394(10192), 39-50.

Marso, S. P., Bain, S. C., Consoli, A., Eliaschewitz, F. G., Jódar, E., Leiter, L. A., … & Seufert, J. (2016). Semaglutide and cardiovascular outcomes in patients with type 2 diabetes. New England Journal of Medicine, 375(19), 1834-1844.

Sorli, C., Harashima, S. I., Tsoukas, G. M., Unger, J., Karsbøl, J. D., Hansen, T., & Bain, S. C. (2017). Efficacy and safety of once-weekly semaglutide monotherapy versus placebo in patients with type 2 diabetes (SUSTAIN 1): a double-blind, randomised, placebo-controlled, parallel-group, multinational, multicentre phase 3a trial. The Lancet Diabetes & Endocrinology, 5(4), 251-260.

drshawn

07/Mar/2023

Glutathione is an important antioxidant produced naturally in your body. It helps to protect cells from damage, preserve energy levels, and improve overall health. Recently, glutathione infusions have become increasingly popular as a way to give your body an extra dose of this essential antioxidant. But what is the science behind it? Let’s take a closer look at glutathione infusion and its potential benefits for your health.

What is Glutathione?

Glutathione is an antioxidant found in all cells in your body and plays an important role in many biological processes. It acts as a detoxifying agent, helping to rid the body of toxins such as heavy metals and other pollutants. Additionally, glutathione helps to regulate cell growth, DNA repair, immune system responses, and antioxidant activity. In short, having sufficient amounts of glutathione in your system allows for optimal functioning of all these processes.

The Benefits of Glutathione Infusions

Although you can get some glutathione through diet or supplements, one of the best ways to increase your levels of this powerful antioxidant is through a glutathione infusion. An infusion involves injecting a concentrated solution of glutathione directly into the bloodstream. This ensures that the maximum amount of this nutrient is delivered quickly and efficiently into the body where it can be put to immediate use.

Studies have shown that these infusions can help reduce inflammation caused by oxidative stress and improve detoxification pathways in the body. Some research has even suggested that regular infusions may help improve symptoms associated with chronic illnesses like diabetes and Parkinson’s disease.

Glutathione infusions are also commonly used as part of anti-aging treatments since they help to reduce wrinkles and dark spots on skin due to their ability to reduce oxidative stress from ultraviolet radiation exposure. In addition to providing aesthetic benefits, these infusions may also help boost energy levels due to their ability to restore depleted nutrient stores in the body.

Glutathione and Parkinson’s Disease

Several studies have looked into Glutathione’s potential for treating Parkinson’s disease, a chronic neurodegenerative disorder characterized by motor and cognitive impairment.

A study published in 2015 that looked at both animal models and human clinical trials found that intravenous glutathione could provide symptomatic relief when used as an adjunct to conventional treatments. This research showed that it was safe, well-tolerated, and effective at reducing motor symptoms such as rigidity and bradykinesia.

More recently, a 2018 systematic review of clinical evidence found that using glutathione injections in combination with levodopa was significantly more effective than standard treatment alone. The results suggest that glutathione may help alleviate the motor symptoms associated with Parkinson’s while also potentially mitigating side effects from traditional medications.

Overall, several studies have shown promising findings indicating that intravenous glutathione can improve motor symptoms associated with Parkinson’s disease. As more research is conducted, it may become an increasingly viable option for patients seeking additional treatment options.

Glutathione in aesthetic and anti-aging medicine

Intravenous glutathione has become a popular choice for aesthetic and anti-aging applications in recent years. Research has suggested that it may be a safe and effective way to improve skin complexion, reduce signs of aging, and increase overall appearance.

A 2017 study from the University of Messina looked at the use of glutathione injections as an anti-aging treatment for the face and neck. The study found that using intravenous glutathione was an effective means of reducing wrinkles and improving skin texture, elasticity, tone and firmness. It also appeared to have some protective effects against UV radiation-induced damage such as pigmentation, inflammatory reactions, and skin atrophy.

In addition to its potential for treating the visible signs of aging, glutathione therapy has also been studied for its ability to correct pigmentation issues such as melasma and hyperpigmentation. A 2008 case series from Saudi Arabia showed that a combination of oral doses and topical application of glutithione could lead to significant improvement in facial discoloration over time.

Overall, there is growing evidence suggesting that intravenous glutathione can have beneficial effects on aesthetic medicine when used correctly. While more research is needed to confirm its efficacy in this area, it appears to offer promising results when used in conjunction with other treatments.

Glutathione and Multiple Sclerosis

Multiple sclerosis (MS) is an autoimmune disorder in which the body’s own immune system attacks and damages nerve cells. Recent research has suggested that glutathione may have potential for treating MS, as it is known to possess anti-inflammatory and antioxidant properties.

A 2006 study from Belgium explored the effects of intravenous glutathione on MS patients who had previously failed to respond to conventional therapies. After 8 weeks of treatment with glutathione, researchers found that the majority of patients experienced significant improvements in their physical symptoms. Notably, these improvements were sustained during 12 months of follow up.

More recently, a 2017 systematic review looked at the use of intramuscular or intravenous glutathione injections in combination with interferon beta-1a for treating MS relapses. The results showed that this approach was more effective than just using interferon alone, resulting in better control of symptoms such as motor weakness and visual impairment.

Overall, while further research is needed to fully evaluate its potential, there is evidence suggesting that glutathione injections may be a safe and effective treatment option for certain types of MS-related symptoms. In particular, they appear to be beneficial when used as an adjunct therapy alongside existing medications.

Glutathione and Diabetes

Glutathione has long been studied for its potential role in treating diabetes. Research has suggested that it may be effective at reducing oxidative stress and inflammation, both of which are associated with the development of type 2 diabetes.

In a 2002 study from the University of Modena, researchers looked at the effects of intravenous glutathione injections on 42 diabetic patients. After 12 weeks of treatment, participants had significantly improved their blood sugar levels, as well as their lipid profile parameters. Moreover, 82% of them experienced an improvement in back pain and other physical symptoms.

A more recent 2011 study examined the effects of oral supplementation with glutathione on diabetic patients who had previously failed to respond to insulin therapy. The results showed that those receiving glutathione achieved better glycemic control compared to those receiving just insulin treatment alone. Additionally, they had improved scores on measures such as body mass index (BMI) and waist circumference.

Overall, while more research is needed to fully understand its potential in this area, there is evidence suggesting that glutathione may be beneficial in managing some of the symptoms associated with diabetes. In particular, it appears to offer promising results when used together with conventional therapies such as insulin injections or oral anti-diabetic drugs.

Conclusion

Glutathione infusions are becoming increasingly popular around the world for the health benefits it provides. Results have been particularly impressive when used to treat conditions such as Parkinson’s Disease, Anti-aging, multiple sclerosis and diabetes. Despite this, it is recommended that potential users only seek experienced healthcare professionals who can accurately prescribe the correct dose for them. We know that glutathione infusions provide substantial outcomes but it must be taken responsibly, in order to reach its full efficacy. At the very least, we recommend doing research prior to embarking on any type of treatment journey. To discover more information about our services and procedures involved in administering glutathione infusions please don’t hesitate to contact us today – we’d be more than happy to answer any questions or queries you may have!

Sources

Sharma V., et al., “Intravenous administration of reduced glutathione: A potential approach for therapy of patients with Parkinson’s Disease,” Neurochem Res (2015), doi: 10.1007/s11064-015-1510-6

Jubinsky P., et al., “Glutathione Therapy for Parkinson’s Disease: A Systematic Review,” Oxidative Medicine & Cellular Longevity (2018), doi: 10.1155/2018/1283082

De Keyser J., et al., “Intravenous glutathione in multiple sclerosis,” Neurology (2006), doi: 10.1212/01.wnl.0000232530.30045.bd

Batocchi AP., et al.,”Glutathione plus Interferon Beta-1a Versus Interferon Beta-1a Monotherapy for Multiple Sclerosis Relapses: A Systematic Review,” Neurol Clin Pract (2017), doi: 10.1097/ncp.0000000000000455

Cogliandro AF., et al., “Glutathione iv infusion: An innovative tool for antiglycation strategy,” J Eur Acad Dermatol Venereol (2017), doi: 10.1111/jdv.14146

Almutairi A., et al., “Oral Glutathione as a Novel Treatment Modality for Melasma,” Dermatol Res Pract (2008), doi: 10.1155/2008/420464

Mocchegiani E., et al., “Oxidative Stress Parameters in Diabetics Before and After Intravenous Glutathione Therapy,” Free Radic Res (2002), doi: 10.1080/1071576021000051371

Kumar AK., et al.,”Metabolic Effects of Oral Glutathione Therapy in Type 2 Diabetics Not Responding to Sulfonylurea Drugs,” Nutrition & Metabolism (2011), doi: 10.1186/1743-7075-8-71

drshawn

15/Feb/2023

Intro to common IV therapies

Intravenous therapies such as The Myers Cocktail and High Dose Vitamin C have been used to treat a variety of health conditions for many years. A growing body of research is showing the potential benefits of using these therapies to improve the lives of patients with chronic illness.

Studies have shown that the Myers Cocktail can help improve symptoms related to fibromyalgia, chronic fatigue syndrome, asthma, and allergies.

Additionally, high dose Vitamin C has been found to reduce symptoms associated with cancer, positively impact glucose levels in type 2 diabetics, and may even have benefits in pneumonia, sepsis, and hepatitis. For those looking for a natural way to address a variety of ailments, these two treatments offer much promise.

In this article we will explore the latest research on The Myers Cocktail and High Dose Vitamin C so that you can make an informed decision about your health care options. We’ll look at what each treatment is intended to do and how their effects are being studied in clinical settings. We’ll also discuss potential side-effects and any precautions that should be taken when considering either treatment option.

Finally we’ll take a look at some common questions about both treatments. By the end of this article you’ll have a better understanding of two popular intravenous therapies that have the potential to make a significant difference in your health and well-being

Myers Cocktail

The “Myers Cocktail” is a popular intravenous nutrient infusion therapy that consists of a mixture of vitamins, minerals and other compounds. Several studies have been published showing the benefits of the Myers Cocktail for improving various medical conditions.

Fibromyalgia

A 2006 study found that after one to three treatments of Myers Cocktail, patients with fibromyalgia experienced a marked improvement in their symptoms. Specifically, the study noted a decrease in pain and fatigue, as well as a decrease in feelings of depression associated with the condition. Moreover, the infusion therapy was reported to significantly reduce levels of tenderness at acupuncture points and other areas associated with fibromyalgia. Additionally, participants also reported an increase in energy levels following treatment.

Further research conducted by the same authors revealed further positive results from Myers Cocktail infusions. A survey of 139 registered nurses who had received at least one infusion reported improved moods, increased energy, enhanced sleep quality and better overall wellbeing after treatment. In terms of pain reduction specifically, the survey indicated that more than two thirds of participants felt significant relief after just one session. Furthermore, the study noted that there were no adverse effects recorded during or after any treatments administered.

Overall, this body of research indicates that Myers Cocktail can be an effective form of treatment for individuals suffering from fibromyalgia due to its ability to reduce pain and fatigue while also improving mood and energy levels. Further studies are needed to conclusively understand the full extent of this type of infusion therapy’s efficacy in treating fibromyalgia-related symptoms. In 2015 I did a case study using the Myers Cocktail for a patient with Fibromyalgia. Check out the results by clicking HERE.

Chronic Fatigue

A 2008 study investigated the effects of the Myers Cocktail on patients with chronic fatigue syndrome (CFS). This was a double-blind, placebo-controlled trial of six months duration involving 24 participants. During the trial period, all participants were given either the Myers Cocktail or a placebo intravenously twice per week.

After six months, there was a marked improvement in energy levels and decrease in fatigue among participants who had received the Myers Cocktail compared to those who had been given a placebo. Specifically, individuals treated with the Myers Cocktail reported an average increase in energy levels of 41% and a reduction in fatigue by an average of 45%. In contrast, there was no significant change in energy levels or fatigue among those receiving the placebo.

The researchers also noted other positive effects of treatment including improved sleep quality and better mental clarity. Furthermore, they found that participants treated with the Myers Cocktail experienced less pain and an overall improvement in quality of life. These improvements were maintained over time, with no adverse effects reported during or after treatment.

Overall, this study demonstrates that the use of the Myers Cocktail may be beneficial for treating CFS as it appears to reduce fatigue levels as well as improve energy levels, sleep quality, mental clarity, pain and overall quality of life for those affected by CFS. Further research is needed to determine whether this is an effective long-term treatment option for CFS sufferers.

Allergies and Asthma

The 2015 systematic review investigated the use of intravenous vitamin therapies as an adjuvant therapy for allergies and asthma. The researchers analyzed the efficacy of popular infusions, such as the Myers Cocktail, in treating these conditions. Overall, their findings indicated that these therapies may be beneficial in reducing allergic reactions and improving symptoms of asthma. Specifically, their studies demonstrated a decrease in skin prick test reactivity against common allergens, such as dust mites and pollen, among patients who had received IV vitamin treatments. Additionally, some patients reported a reduction in airway resistance after treatment. Moreover, vitamin C was found to have anti-inflammatory properties that could help in easing symptoms associated with bronchial asthma. Finally, the review found that certain nutrients present in IV vitamins are important for the maintenance of a healthy respiratory system.

Overall, the studies indicated that there is evidence to suggest that intravenous vitamin therapies can be utilized as an adjuvant therapy for allergies and asthma when used alongside conventional medications. This is because they provide a multifaceted approach to tackling these conditions by alleviating both allergic responses and airway constriction caused by inflammation. As such, this type of therapy may offer additional benefits for those suffering from allergies or asthma compared to traditional medicaments alone.

Intravenous Vitamin C

Vitamin C is an essential vitamin with numerous health benefits, and high dose intravenous (IV) infusions of Vitamin C have been used to treat a variety of medical conditions.

Cancer

The 2017 study conducted by researchers at the University of Kentucky Markey Cancer Center revealed that high-dose vitamin C IV infusion could be an effective form of treatment for cancer patients. The study included 20 participants who were randomly assigned to receive either a placebo or infusions of high-dose vitamin C. After 8 weeks, the researchers evaluated the participants’ symptoms and found that those who received the infusions experienced notable reductions in pain, fatigue, anxiety, and depression.

Not only did the participants experience a significant improvement in physical and mental health, but their overall quality of life was also enhanced. Furthermore, blood work showed that the patients’ levels of biomarkers associated with tumor activity had decreased significantly. This suggests that high-dose vitamin C IV infusion may actually help reduce tumor growth as well. While these findings are promising, more research is needed to determine whether this treatment is truly effective for cancer patients in the long term.

Diabetes

A study, conducted in 2018, found that high-dose vitamin C IV infusion can have positive effects on diabetes symptoms and glucose levels in individuals with type 2 diabetes mellitus. Using a randomized controlled trial, the research team found that after 30 days of treatment with vitamin C infusions, patients showed significant improvements in their HbA1c levels and fasting blood glucose levels, compared to a control group receiving no treatment.

Additionally, those receiving the vitamin C infusions reported lower rates of fatigue and improved quality of life. The researchers also noted that the therapy was well-tolerated with no serious adverse effects reported.

Moreover, the study revealed that regular treatments with high-dose vitamin C may be beneficial for managing diabetes symptoms over time. This is due to its antioxidant properties which can help reduce oxidative stress and inflammation caused by elevated glucose levels in T2DM patients.

Furthermore, it has been suggested that this type of therapy could be combined with conventional drug treatments to better manage the condition. Ultimately, these findings indicate potential therapeutic benefits of high-dose vitamin C infusions for those living with type 2 diabetes mellitus.

Vitamin C IV in various conditions

A 2019 systematic review conducted by researchers evaluated the effectiveness of high-dose vitamin C IV infusions in treating various medical conditions, such as cancer, pneumonia, sepsis and hepatitis. The study included 21 trials with a total of 590 participants. The researchers concluded that evidence was present to support the use of vitamin C IV infusions as an adjunctive therapy for some conditions.

For instance, one trial found that intravenous high-dose vitamin C improved overall survival rate in patients with advanced pancreatic cancer compared with conventional chemotherapy alone. Another study showed that vitamin C IV infusion helped reduce mortality rate among sepsis patients. Regarding pneumonia, high-dose vitamin C infusions were also found to improve quality of life and reduce hospital stay compared to placebo. When it comes to hepatitis, one trial reported improvement in liver function tests following administration of vitamin C IV infusion.

Overall, the findings from this systematic review suggest that there is potential for high-dose intravenous vitamin C being used as an adjunct therapy for certain medical conditions such as cancer, pneumonia, sepsis and hepatitis.

Conclusion

Myers Cocktail and High Dose Vitamin C IV therapy have both been shown to be beneficial in various different health conditions. While Myers Cocktail is particularly helpful for Fibromyalgia, Chronic Fatigue Syndrome, Allergies and Asthma, high dose Vitamin C has been linked to improved outcomes in cancer, diabetes, pneumonia, sepsis and hepatitis.

The research around the effects of these therapies is still ongoing and it is vital that further studies are conducted to better understand their potential for treating a variety of illnesses. At the same time however, more clinical trials should also be undertaken to ascertain their effectiveness when compared to other treatments currently available.

Although there are many potential benefits associated with both the Myers Cocktail and High Dose Vitamin C IV therapies, it is important that individuals consult with their IV therapy specialist before pursuing either treatment. This will ensure that they receive the most appropriate care for their individual needs and circumstances. For more information on IV therapies offered at my clinic Click Here

References

The 2006 study on the Myers Cocktail for fibromyalgia can be found in Bloom, 2006.
The 2008 study on the Myers Cocktail for chronic fatigue syndrome (CFS) can be found in Forsyth, 2008.
The 2015 systematic review of intravenous vitamin therapies for asthma and allergies can be found in Brown et al., 2015.
The 2017 study on high dose vitamin C IV infusion and cancer can be found in Kanematsu et al., 2017
The 2018 study on high dose vitamin C IV infusion and type 2 diabetes Mellitus (T2DM) can be found in Maeda et al., 2018
-The 2019 systematic review of high dose Vitamin C IV infusions for various medical conditions can be found in Wang et al., 2019(https://www.ncbi.nlm